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公开(公告)号：US11202810B2
公开(公告)日：2021-12-21
申请号：US16372635
申请日：2019-04-02
IPC分类号： A61K35/742 , A61P1/00 , A61K38/43 , A61K9/48 , A61K9/00
摘要： The present invention discloses a stable probiotic composition comprising Bacillus coagulans individually and/or in combination with multi-enzyme complex for the utilization of lactose and therapeutic management of lactose intolerance. It also discloses a method for the management of lactose intolerance using composition comprising Bacillus coagulans individually and/or in combination with multi-enzyme complex.
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公开(公告)号：US20200316139A1
公开(公告)日：2020-10-08
申请号：US16372635
申请日：2019-04-02
IPC分类号： A61K35/742 , A61P1/00 , A61K9/00 , A61K9/48 , A61K38/43
摘要： The present invention discloses a stable probiotic composition comprising Bacillus coagulans individually and/or in combination with multi-enzyme complex for the utilization of lactose and therapeutic management of lactose intolerance. It also discloses a method for the management of lactose intolerance using composition comprising Bacillus coagulans individually and/or in combination with multi-enzyme complex.
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公开(公告)号：US20190085277A1
公开(公告)日：2019-03-21
申请号：US16136475
申请日：2018-09-20
申请人： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Shaheen Majeed , Kirankumar Beede
发明人： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Shaheen Majeed , Kirankumar Beede
IPC分类号： C12C12/00 , A23L33/135 , A61K35/742 , A61K9/00
摘要： A probiotic-alcoholic beverage composition comprising Bacillus coagulans is disclosed herein wherein the said spore or vegetative cell of Bacillus coagulans exhibited high recovery, tolerability, compatibility and viability of spores and vegetative cells after brewing. Methods for brewing an alcoholic beverage composition comprising Bacillus coagulans wherein said spore or bacterium is added during pre-fermentation, during fermentation and post fermentation stages are also disclosed.
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公开(公告)号：US20180344627A1
公开(公告)日：2018-12-06
申请号：US15996725
申请日：2018-06-04
申请人： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Shaheen Majeed , Lakshmi Mundkur
发明人： Muhammed Majeed , Kalyanam Nagabhushanam , Sivakumar Arumugam , Furqan Ali , Shaheen Majeed , Lakshmi Mundkur
摘要： Disclosed are the skin care applications of a composition containing the partially purified extracellular metabolite isolated from Bacillus coagulans MTCC 5856. More specifically, the invention discloses the ability of the partially purified extracellular metabolite isolated from Bacillus coagulans MTCC 5856 to confer protection to the skin fibroblasts against UV induced cell damage and apoptosis, oxidative stress and inflammation.
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公开(公告)号：US10806760B2
公开(公告)日：2020-10-20
申请号：US15995393
申请日：2018-06-01
IPC分类号： A61K35/742 , A61P1/14 , C12N1/20 , C12R1/07
摘要： Disclosed are the methods and compositions for the reduction of intestinal gas/flatulence. Specifically a method for reducing flatulence using a composition containing probiotic bacteria Bacillus coagulans MTCC 5856 is disclosed. More specifically, the invention discloses a method for inhibiting the growth of microorganisms that facilitate the production of intestinal gas, using a composition containing probiotic bacteria Bacillus coagulans MTCC 5856.
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公开(公告)号：US10792295B2
公开(公告)日：2020-10-06
申请号：US16001096
申请日：2018-06-06
IPC分类号： A61K31/7024 , A61P31/04 , A61K35/742
摘要： Disclosed are compositions containing at least 10% w/w or above of 1-O-galloyl-β-D-glucose (β-glucogallin) which additionally comprising of about 10% w/w to greater than 60% w/w total mucic acid gallates including mucic acid 1,4-lactone 5-O-gallate, mucic acid 2-O-gallate, mucic acid 6-Methyl ester 2-O-gallate, mucic acid 1-Methyl ester 2-O-gallate and ellagic acid, and a probiotic bacteria Bacillus coagulans MTCC 5856, individually or in combination for inhibiting the growth and managing infections of Helicobacter pylori.
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公开(公告)号：US20190328798A1
公开(公告)日：2019-10-31
申请号：US16396876
申请日：2019-04-29
申请人： Muhammed Majeed , Kalyanam Nagabhushanam , Furqan Ali , Sivakumar Arumugam , Shaheen Majeed , Lakshmi Mundkur , Anurag Pande
发明人： Muhammed Majeed , Kalyanam Nagabhushanam , Furqan Ali , Sivakumar Arumugam , Shaheen Majeed , Lakshmi Mundkur , Anurag Pande
IPC分类号： A61K35/742 , C12N1/20
摘要： The present invention discloses a composition comprising heat inactivated spores and/or comprising heat inactivated vegetative cells of probiotic bacteria Bacillus coagulans, and a process for preparing the same. The invention also discloses a method of modulating immune function in mammals by activating macrophages, using a composition comprising Bacillus coagulans in the form of live or heat inactivated spore and/or vegetative cells.
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公开(公告)号：US20180353555A1
公开(公告)日：2018-12-13
申请号：US15995393
申请日：2018-06-01
IPC分类号： A61K35/742 , C12N1/20 , A61P1/14
摘要： Disclosed are the methods and compositions for the reduction of intestinal gas/flatulence. Specifically a method for reducing flatulence using a composition containing probiotic bacteria Bacillus coagulans MTCC 5856 is disclosed. More specifically, the invention discloses a method for inhibiting the growth of microorganisms that facilitate the production of intestinal gas, using a composition containing probiotic bacteria Bacillus coagulans MTCC 5856.
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公开(公告)号：US20180344754A1
公开(公告)日：2018-12-06
申请号：US16001096
申请日：2018-06-06
IPC分类号： A61K31/7024 , A61K35/742 , A61P31/04
摘要： Disclosed are compositions containing at least 10% w/w or above of 1-O-galloyl-β-D-glucose (β-glucogallin) which additionally comprising of about 10% w/w to greater than 60% w/w total mucic acid gallates including mucic acid 1,4-lactone 5-O-gallate, mucic acid 2-O-gallate, mucic acid 6-Methyl ester 2-O-gallate, mucic acid 1-Methyl ester 2-O-gallate and ellagic acid, and a probiotic bacteria Bacillus coagulans MTCC 5856, individually or in combination for inhibiting the growth and managing infections of Helicobacter pylori.
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公开(公告)号：US11298381B2
公开(公告)日：2022-04-12
申请号：US16396876
申请日：2019-04-29
申请人： Muhammed Majeed , Kalyanam Nagabhushanam , Furqan Ali , Sivakumar Arumugam , Shaheen Majeed , Lakshmi Mundkur , Anurag Pande
发明人： Muhammed Majeed , Kalyanam Nagabhushanam , Furqan Ali , Sivakumar Arumugam , Shaheen Majeed , Lakshmi Mundkur , Anurag Pande
IPC分类号： A01N63/00 , A61K35/742 , C12N1/20
摘要： The present invention discloses a composition comprising heat inactivated spores and/or comprising heat inactivated vegetative cells of probiotic bacteria Bacillus coagulans, and a process for preparing the same. The invention also discloses a method of modulating immune function in mammals by activating macrophages, using a composition comprising Bacillus coagulans in the form of live or heat inactivated spore and/or vegetative cells.
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