公开(公告)号：US07294137B2

公开(公告)日：2007-11-13

申请号：US10109112

申请日：2002-03-27

申请人： Patrick Rivelli, Jr. ,  Alec Piplani ,  Sean Donahue ,  Arani Bose ,  Alexander Leynov

发明人： Patrick Rivelli, Jr. ,  Alec Piplani ,  Sean Donahue ,  Arani Bose ,  Alexander Leynov

IPC分类号： A61M29/00

CPC分类号： A61M39/105 ,  A61F2/966 ,  A61M2025/0004 ,  A61M2025/0042

摘要： A device and method for permitting multi-modal treatment of vascular lesions are disclosed. The device includes an outer delivery catheter, an inner delivery catheter, and a guidewire. The catheter is designed to pass through the inner lumen of the outer delivery catheter, and the guidewire is designed to pass through the inner lumen of the inner delivery catheter. A stent may be loaded inside the outer delivery catheter, with the distal tip of the inner delivery catheter abutting against the proximal end of the self-expanding stent, for pushing the stent distally through the outer delivery catheter.

摘要翻译： 公开了允许血管病变多模态治疗的装置和方法。 该装置包括外部输送导管，内部输送导管和导丝。 导管被设计成穿过外部输送导管的内腔，并且导丝被设计成穿过内部输送导管的内腔。 支架可以装载在外部输送导管内部，其中内部输送导管的远侧末端抵靠自扩张支架的近端，用于将支架向远侧推动通过外部输送导管。

公开(公告)号：US08911487B2

公开(公告)日：2014-12-16

申请号：US12888137

申请日：2010-09-22

申请人： Eric Bennett ,  Erin Vitus ,  Matt Vargas ,  Arani Bose ,  Stephen Pons ,  Ben Tompkins ,  David Barry

发明人： Eric Bennett ,  Erin Vitus ,  Matt Vargas ,  Arani Bose ,  Stephen Pons ,  Ben Tompkins ,  David Barry

IPC分类号： A61F2/06 ,  A61M25/01

CPC分类号： A61F2/95 ,  A61F2002/9511 ,  A61M25/01 ,  A61M25/0136 ,  A61M25/0147

摘要： A system for mechanically deploying intraluminal implants is disclosed. The system is used with an implant that is delivered and/or deployed via a pull wire and includes a handle having a funnel and receiving channel for receiving the pull wire, a slider having a thumb grip and a wedge, and a shuttle having a grabber for grasping the pull wire. The thumb grip is pulled proximally to retract the wedge to cause the grabber to grasp the wire and retract the shuttle but not the wire. An extension spring linked between the slider and the shuttle abruptly pulls the shuttle to retract the pull wire after the slider is fully retracted.

摘要翻译： 公开了一种用于机械部署管腔内植入物的系统。 该系统与通过拉线输送和/或部署的植入物一起使用，并且包括具有漏斗的手柄和用于接收拉线的接收通道，具有拇指手柄和楔块的滑块以及具有抓取器的梭子 用于抓住拉丝。 拇指把手被向近侧拉动以缩回楔块，以使抓取器抓住线并使梭子收回而不是线。 在滑块完全缩回之后，连接在滑块和梭子之间的拉伸弹簧突然拉动梭子以缩回拉线。

公开(公告)号：US20130331882A1

公开(公告)日：2013-12-12

申请号：US13680596

申请日：2012-11-19

申请人： Ben Tompkins ,  Arani Bose ,  Delilah Hui ,  David Barry ,  Stephen Pons ,  Aleksander Leynov

发明人： Ben Tompkins ,  Arani Bose ,  Delilah Hui ,  David Barry ,  Stephen Pons ,  Aleksander Leynov

IPC分类号： A61B17/12

CPC分类号： A61B17/12154 ,  A61B17/12022 ,  A61B17/12113 ,  A61B17/1214 ,  A61B17/12145 ,  A61B17/12181 ,  A61B2017/00871 ,  A61B2017/12054 ,  A61B2017/1209

摘要： Embolic coil implant systems and methods whereby coils are mechanically detachable are disclosed. The coils include a retention element that may be releasably retained within the distal end of an implant tool. The implant tool may include a fulcrum configured to engage a first filament and prevent the release of the coil when the first filament is engaged. Alternatively, an urging means and aperture may be disposed within the sidewall of the implant tool, and a first filament may, in conjunction with the aperture and sidewall, releasably retain the coil until the first filament is withdrawn. The implant tool may also include an alignment member for aligning the first filament.

摘要翻译： 公开了一种栓塞线圈植入系统及其线圈可机械拆卸的方法。 线圈包括可释放地保持在植入物工具的远端内的保持元件。 植入工具可以包括构造成接合第一细丝并且当第一细丝接合时防止线圈释放的支点。 或者，推动装置和孔可以设置在植入工具的侧壁内，并且第一细丝可以与孔和侧壁一起可释放地保持线圈直到第一丝被拉出。 植入工具还可以包括用于对准第一细丝的对准构件。

公开(公告)号：US20100204672A1

公开(公告)日：2010-08-12

申请号：US12370288

申请日：2009-02-12

申请人： Arthur John Lockhart ,  Arani Bose ,  David Barry

发明人： Arthur John Lockhart ,  Arani Bose ,  David Barry

IPC分类号： A61M1/00

CPC分类号： A61B17/22 ,  A61B2017/22042 ,  A61B2017/22044 ,  A61B2017/22079 ,  A61B2017/22094 ,  A61B2217/005

摘要： A thromboembolic removal system for treating ischemic stroke, including a guide and occlusion catheter, an aspiration catheter, an aspiration pump, and a thromboembolic separator. During aspiration of thromboembolic material through the aspiration catheter, the separator element is advanced from and retracted into the catheter lumen to break up or prevent clogs or flow restrictions formed by the thromboembolic material. Longitudinal channels in the separator allow aspiration through the aspiration catheter to continue even when the separator is disposed in the aspiration catheter lumen.

摘要翻译： 用于治疗缺血性卒中的血栓栓塞去除系统，包括引导和闭塞导管，抽吸导管，抽吸泵和血栓栓塞分离器。 在通过抽吸导管抽吸血栓栓塞材料期间，分离器元件从导管内腔前进并缩回到导管腔中，以分解或防止由血栓栓塞材料形成的堵塞或流动限制。 分离器中的纵向通道允许通过抽吸导管的抽吸继续，即使当分离器设置在抽吸导管腔中时。

公开(公告)号：US20100174269A1

公开(公告)日：2010-07-08

申请号：US12498752

申请日：2009-07-07

申请人： Ben Tompkins ,  Arani Bose ,  Delilah Hui ,  David Barry ,  Stephen Pons ,  Aleksander Leynov

发明人： Ben Tompkins ,  Arani Bose ,  Delilah Hui ,  David Barry ,  Stephen Pons ,  Aleksander Leynov

IPC分类号： A61M37/00

CPC分类号： A61B17/12154 ,  A61B17/12022 ,  A61B17/12113 ,  A61B17/1214 ,  A61B17/12145 ,  A61B17/12181 ,  A61B2017/00871 ,  A61B2017/12054 ,  A61B2017/1209

摘要： Embolic coil implant systems and methods whereby coils are mechanically detachable are disclosed. The coils include a retention element that may be releasably retained within the distal end of an implant tool. The implant tool may include a fulcrum configured to engage a first filament and prevent the release of the coil when the first filament is engaged. Alternatively, an urging means and aperture may be disposed within the sidewall of the implant tool, and a first filament may, in conjunction with the aperture and sidewall, releasably retain the coil until the first filament is withdrawn. The implant tool may also include an alignment member for aligning the first filament.

摘要翻译： 公开了一种栓塞线圈植入系统及其线圈可机械拆卸的方法。 线圈包括可释放地保持在植入物工具的远端内的保持元件。 植入工具可以包括构造成接合第一细丝并且当第一细丝接合时防止线圈释放的支点。 或者，推动装置和孔可以设置在植入工具的侧壁内，并且第一细丝可以与孔和侧壁一起可释放地保持线圈直到第一丝被拉出。 植入工具还可以包括用于对准第一细丝的对准构件。

公开(公告)号：US06669721B1

公开(公告)日：2003-12-30

申请号：US09789535

申请日：2001-02-22

申请人： Arani Bose ,  Peter Kim Nelson

发明人： Arani Bose ,  Peter Kim Nelson

IPC分类号： A61F206

CPC分类号： A61F2/06 ,  A61B17/12022 ,  A61B17/12113 ,  A61B17/12118 ,  A61B17/1214 ,  A61B17/12172 ,  A61B17/12186 ,  A61B17/1219 ,  A61B2017/00831 ,  A61B2017/00995 ,  A61F2/82 ,  A61F2/88 ,  A61F2002/30062 ,  A61F2002/823 ,  A61F2210/0004 ,  A61F2230/005 ,  A61F2230/0071 ,  A61F2230/0095

摘要： Devices for excluding aneurysms and treating atherosclerotic disease, for intra-aneurysmal occlusion, and devices for preventing distal emboli. The devices are generally pliable and collapsible thin film devices which can be delivered via a microcatheter into the desired location where they are deployed and undergo either a shape memory phase transformation or in situ polymerization to assume the stable configuration of a permanent endoluminal prosthesis. Prior to being caused to assume their final shape, the devices remain soft, collapsible and pliable to ensure atraumatic delivery through the vascular system. Upon reaching the endoluminal defect in the vessel, the device is extruded from the microcatheter. Devices are also provided for retrieving clots.

公开(公告)号：US20090030400A1

公开(公告)日：2009-01-29

申请号：US12178521

申请日：2008-07-23

申请人： Arani Bose ,  David Barry ,  Delilah Hui ,  Ben Tompkins

发明人： Arani Bose ,  David Barry ,  Delilah Hui ,  Ben Tompkins

IPC分类号： A61M25/088

CPC分类号： A61M25/0054 ,  A61M25/0023 ,  A61M25/005 ,  A61M25/0053 ,  A61M25/0068 ,  A61M25/008 ,  A61M25/0108 ,  A61M27/006 ,  A61M2025/0046

摘要： A delivery catheter for accessing the intra-cranial vascular includes a rigid proximal section and a distal section having an outer diameter and flexibility suitable for advancement into the intra-cranial vasculature, such as the Petrous segment or the Cavernous segment of the internal carotid artery. The wall thickness and rigidity of the catheter decrease from the proximal section to the distal section, preferably in discrete segments each having reduced wall thickness and/or durometer relative to proximally adjacent sections. An intra-cranial access system includes the delivery catheter and a selection catheter insertable through the lumen of the delivery catheter. The selection catheter is shaped to facilitate selection of the target branch of the neurovasculature off the aortic arch and allows the delivery catheter to be advanced over the selection catheter into the selected branch.

摘要翻译： 用于进入颅内血管的输送导管包括刚性近端部分和远端部分，其具有适合于进入颅内脉管系统的外径和弹性的远端部分，例如内侧颈动脉的石质部分或海绵状部分。 导管的壁厚度和刚度从近端部分到远侧部分减小，优选地相对于近侧相邻部分具有减小的壁厚度和/或硬度的离散部分。 颅内存取系统包括输送导管和可插入通过输送导管内腔的选择导管。 选择导管被成形为便于从主动脉弓上选择神经血管的目标分支，并允许输送导管在选择导管上前进到所选择的分支中。

公开(公告)号：US06605111B2

公开(公告)日：2003-08-12

申请号：US09789531

申请日：2001-02-22

申请人： Arani Bose ,  Peter Kim Nelson

发明人： Arani Bose ,  Peter Kim Nelson

IPC分类号： A61F206

CPC分类号： A61F2/06 ,  A61B17/12022 ,  A61B17/12113 ,  A61B17/12118 ,  A61B17/1214 ,  A61B17/12172 ,  A61B17/12186 ,  A61B17/1219 ,  A61B2017/00831 ,  A61B2017/00995 ,  A61F2/82 ,  A61F2/88 ,  A61F2002/30062 ,  A61F2002/823 ,  A61F2210/0004 ,  A61F2230/005 ,  A61F2230/0071 ,  A61F2230/0095

摘要： Devices for excluding aneurysms and treating atherosclerotic disease, for intra-aneurysmal occlusion; and devices for preventing distal emboli. The devices are generally pliable and collapsible thin film devices which can be delivered via a microcatheter into the desired location where they are deployed and undergo either a shape memory phase transformation or in situ polymerization to assume the stable configuration of a permanent endoluminal prosthesis. Prior to being caused to assume their final shape, the devices remain soft, collapsible and pliable to ensure atraumatic delivery through the vascular system. Upon reaching the endoluminal defect in the vessel, the device is extruded from the microcatheter. Devices are also provided for retrieving clots.

摘要翻译： 用于排除动脉瘤和治疗动脉粥样硬化疾病，用于动脉瘤内闭塞的装置; 和用于防止远端栓塞的装置。 这些装置通常是柔韧的和可折叠的薄膜装置，其可以通过微导管递送到所需的位置，在那里它们被展开，并进行形状记忆相变或原位聚合以承受永久性内腔假体的稳定构型。 在使其呈现其最终形状之前，该装置保持柔软，可折叠和柔韧，以确保通过血管系统的无创伤输送。 在达到容器中的腔内缺陷时，该装置从微导管挤出。 还提供了用于检测凝块的装置。

公开(公告)号：US09186151B2

公开(公告)日：2015-11-17

申请号：US13680596

申请日：2012-11-19

申请人： Ben Tompkins ,  Arani Bose ,  Delilah Hui ,  David Barry ,  Stephen Pons ,  Aleksander Leynov

发明人： Ben Tompkins ,  Arani Bose ,  Delilah Hui ,  David Barry ,  Stephen Pons ,  Aleksander Leynov

IPC分类号： A61F2/06 ,  A61B17/12

CPC分类号： A61B17/12154 ,  A61B17/12022 ,  A61B17/12113 ,  A61B17/1214 ,  A61B17/12145 ,  A61B17/12181 ,  A61B2017/00871 ,  A61B2017/12054 ,  A61B2017/1209

摘要： Embolic coil implant systems and methods whereby coils are mechanically detachable are disclosed. The coils include a retention element that may be releasably retained within the distal end of an implant tool. The implant tool may include a fulcrum configured to engage a first filament and prevent the release of the coil when the first filament is engaged. Alternatively, an urging means and aperture may be disposed within the sidewall of the implant tool, and a first filament may, in conjunction with the aperture and sidewall, releasably retain the coil until the first filament is withdrawn. The implant tool may also include an alignment member for aligning the first filament.

摘要翻译： 公开了一种栓塞线圈植入系统及其线圈可机械拆卸的方法。 线圈包括可释放地保持在植入物工具的远端内的保持元件。 植入工具可以包括构造成接合第一细丝并且当第一细丝接合时防止线圈释放的支点。 或者，推动装置和孔可以设置在植入工具的侧壁内，并且第一细丝可以与孔和侧壁一起可释放地保持线圈直到第一丝被拉出。 植入工具还可以包括用于对准第一细丝的对准构件。

公开(公告)号：US20110238147A1

公开(公告)日：2011-09-29

申请号：US12888137

申请日：2010-09-22

申请人： Eric Bennett ,  Erin Vitus ,  Matt Vargas ,  Arani Bose ,  Stephen Pons ,  Ben Tompkins ,  David Barry

发明人： Eric Bennett ,  Erin Vitus ,  Matt Vargas ,  Arani Bose ,  Stephen Pons ,  Ben Tompkins ,  David Barry

IPC分类号： A61F2/84

CPC分类号： A61F2/95 ,  A61F2002/9511 ,  A61M25/01 ,  A61M25/0136 ,  A61M25/0147

摘要： A system for mechanically deploying intraluminal implants is disclosed. The system is used with an implant that is delivered and/or deployed via a pull wire and includes a handle having a funnel and receiving channel for receiving the pull wire, a slider having a thumb grip and a wedge, and a shuttle having a grabber for grasping the pull wire. The thumb grip is pulled proximally to retract the wedge to cause the grabber to grasp the wire and retract the shuttle but not the wire. An extension spring linked between the slider and the shuttle abruptly pulls the shuttle to retract the pull wire after the slider is fully retracted.

摘要翻译： 公开了一种用于机械部署管腔内植入物的系统。 该系统与通过拉线输送和/或部署的植入物一起使用，并且包括具有漏斗的手柄和用于接收拉线的接收通道，具有拇指手柄和楔块的滑块以及具有抓取器的梭子 用于抓住拉丝。 拇指把手被向近侧拉动以缩回楔块，以使抓取器抓住线并使梭子收回而不是线。 在滑块完全缩回之后，连接在滑块和梭子之间的拉伸弹簧突然拉动梭子以缩回拉线。