公开(公告)号：USD564379S1

公开(公告)日：2008-03-18

申请号：US29276248

申请日：2007-01-19

Applicant: Ashwani Kaushal ,  Duncan MacIntyre

Designer： Ashwani Kaushal ,  Duncan MacIntyre

公开(公告)号：US07343185B2

公开(公告)日：2008-03-11

申请号：US10465490

申请日：2003-06-18

Applicant: James Samsoondar ,  Duncan MacIntyre

Inventor： James Samsoondar ,  Duncan MacIntyre

IPC: A61B5/00

CPC classification number: A61B5/1455 ,  A61B5/14532 ,  A61B5/14546

Abstract: The present invention provides a method for identifying a concentration of a compound within a part of a subject. The method involves measuring the amount of electromagnetic radiation reflected by, or transmitted through the part with a detector, and using a quantitative mathematical analysis to determine the concentration of the compound in one, or more than one compartment, including a blood, interstitial, cellular, lymph, or bone compartment, of the part. A corrected concentration of the compound may be then determined within a compartment of interest, or a total concentration of the compound may be accurately determined. Preferably, the compound is glucose. From this determination, a clinical condition in a human or animal may be made by correlating the concentration of a measured compound in the compartment of a part of the human or animal to a clinical condition in need of treatment.

Abstract translation: 本发明提供了用于鉴定受试者部分内的化合物浓度的方法。 该方法包括测量由检测器反射或透过该部分的电磁辐射的量，并使用定量数学分析来确定化合物在一个或多于一个隔室中的浓度，包括血液，间质，细胞 ，淋巴或骨隔室。 然后可以在感兴趣的隔室内确定化合物的校正浓度，或者可以准确地确定化合物的总浓度。 优选地，化合物是葡萄糖。 根据该测定，可以通过将人或动物的一部分的隔室中的测量化合物的浓度与需要治疗的临床病症相关联来进行人或动物的临床状况。

公开(公告)号：USD560529S1

公开(公告)日：2008-01-29

申请号：US29276853

申请日：2007-02-07

Applicant: Ashwani Kaushal ,  Duncan MacIntyre

Designer： Ashwani Kaushal ,  Duncan MacIntyre

公开(公告)号：US20050075546A1

公开(公告)日：2005-04-07

申请号：US10943737

申请日：2004-09-17

Applicant: James Samsoondar ,  Duncan MacIntyre ,  Ashwani Kaushal

Inventor： James Samsoondar ,  Duncan MacIntyre ,  Ashwani Kaushal

IPC: A61B5/00 ,  A61B5/055

CPC classification number: A61B5/0059 ,  A61B2562/0238

Abstract: The present invention provides an apparatus and a method for identifying the risk of a clinical condition in a human or animal by correlating Near Infrared (NIR) absorbance spectral data with one or several parameters including a concentration of one or more substances in the skin, a concentration of one or more substances in skin plus subdermal tissue, a score derived from one or more clinical tests like a stress test on a treadmill, coronary angiography, or intravascular coronary ultrasound. The method determines the concentration of a compound in the skin of a human or animal and comprises the steps of placing a part of the skin against a receptor, directing electromagnetic radiation (EMR) from the near-infrared spectrum onto the skin, measuring a quantity of EMR reflected by, or transmitted through, the skin with a detector; and performing a quantitative mathematical analysis of the quantity of EMR to determine the concentration of the compound, for example free and esterfied cholesterol. An example of a clinical condition is cardiovascular disease.

Abstract translation: 本发明提供了一种用于通过将近红外（NIR）吸收光谱数据与包括皮肤中的一种或多种物质的浓度的一个或几个参数相关联来鉴定人或动物的临床状况的风险的装置和方法， 皮肤中的一种或多种物质和皮下组织的浓度，来自一项或多项临床试验的得分，如跑步机上的压力试验，冠状动脉造影或血管内冠状动脉超声。 该方法确定化合物在人或动物皮肤中的浓度，包括以下步骤：将一部分皮肤放置在受体上，将电磁辐射（EMR）从近红外光谱引导到皮肤上，测量数量 由检测器反射或透过皮肤的EMR; 并对EMR的量进行定量数学分析以确定化合物的浓度，例如游离和酯化的胆固醇。 临床病症的一个例子是心血管疾病。