公开(公告)号：US20150322453A1

公开(公告)日：2015-11-12

申请号：US14653090

申请日：2013-12-13

Applicant: BASF SE

Inventor： Stefan Tresch ,  Doreen Schachtschabel ,  Maciej Pasternak ,  Liliana Parra Rapado ,  Jens Lerchl ,  Thomas Mietzner ,  Martin Laforest

IPC: C12N15/82 ,  C12N9/02 ,  A01N57/16

CPC classification number: C12N15/8274 ,  A01N57/16 ,  C12N9/0071 ,  C12N9/0079 ,  C12Y114/00

Abstract: The present invention refers to method for producing a transgenic plant with increased herbicide tolerance or resistance as compared to a corresponding non-transformed wild type plant, comprising transforming a plant cell or a plant cell nucleus or a plant tissue with a nucleic acid molecule encoding an Alopecurus cytochrome P450 monooxygenase, as well as to the nucleic acid, and plants with increased herbicide tolerance or resistance comprising the nucleic acid of the invention. Furthermore, the present invention refers to methods of controlling weeds at a locus which contains a plant with increased herbicide tolerance or resistance comprising the nucleic acid of the invention.

Abstract translation: 本发明涉及与相应的未转化的野生型植物相比，用于生产具有增加的除草剂耐受性或抗性的转基因植物的方法，其包括用编码一种或多种植物的核酸分子转化植物细胞或植物细胞核或植物组织 斑秃细胞色素P450单加氧酶以及核酸，以及包含本发明核酸的除草剂耐受性或抗性增加的植物。 此外，本发明涉及在包含本发明的核酸的含有增加的除草剂耐受性或抗性的植物的场所控制杂草的方法。

公开(公告)号：US20150126371A1

公开(公告)日：2015-05-07

申请号：US14405942

申请日：2013-05-29

Applicant: BASF SE

Inventor： Matthias Witschel ,  Frank Stelzer ,  Johannes Hutzler ,  Tao Qu ,  Thomas Mietzner ,  Klaus Kreuz ,  Klaus Grossmann ,  Raphael Aponte ,  Hans Wolfgang Hoeffken ,  Frederick Calo ,  Thomas Ehrhardt ,  Anja Simon ,  Liliana Parra Rapado

IPC: A01N43/90 ,  A01N47/20 ,  C07D491/052

CPC classification number: A01N43/90 ,  A01N47/20 ,  C07D311/94 ,  C07D491/052

Abstract: The present invention relates to a pyrazolopyran of the general formula I wherein the variables are defined according to the description, including a tautomer, salt, cleavable prodrug, or mixtures thereof, in particular to said pyrazolopyran for use as a medicament and/or an inhibitor of the enzyme serinehydroxymethyltransferase (SHMT). The invention also relates to a process the preparation of a pyrazolopyran of the formula I, to compositions comprising said compound and processes for the preparation of these compositions. Further it relates to use of the pyrazolopyran of formula I as an herbicide as well as to a method of controlling undesired vegetation.

Abstract translation: 本发明涉及通式I的吡唑并兰，其中根据描述定义变量，包括互变异构体，盐，可切割前药或其混合物，特别是所述吡唑并吡喃用作药物和/或抑制剂 的酶丝氨酸羟甲基转移酶（SHMT）。 本发明还涉及制备式I的吡唑并吡喃的方法，包括所述化合物的组合物和制备这些组合物的方法。 此外，它涉及式I的吡唑并吡喃作除草剂以及控制不希望的植物的方法。

公开(公告)号：US11230717B2

公开(公告)日：2022-01-25

申请号：US15307740

申请日：2014-04-28

Applicant: BASF SE

Inventor： Maciej Pasternak ,  Stefan Tresch ,  Helmut Kraus ,  Johannes Hutzler ,  Jens Lerchl ,  Thomas Mietzner ,  Jill Marie Paulik

IPC: C12N15/82 ,  C12N9/02 ,  A01N43/653 ,  A01N43/713

Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type hydroxyphenyl pyruvate dioxygenase or a mutated hydroxyphenyl pyruvate dioxygenase (mut-HPPD) which is resistant or tolerant to a HPPD-inhibiting herbicide and/or a nucleotide sequence encoding a wild-type homogentisate solanesyl transferase or a mutated homogentisate solanesyl transferase (mut-HST) which is resistant or tolerant to a HPPD-inhibiting herbicide, applying to said site an effective amount of said herbicide. The invention further refers to plants comprising mut-HPPD, and methods of obtaining such plants.

公开(公告)号：US11185075B2

公开(公告)日：2021-11-30

申请号：US16469877

申请日：2017-12-07

Applicant: BASF SE

Inventor： Tobias Seiser ,  Manuel Johannes ,  Matthias Witschel ,  Liliana Parra Rapado ,  Raphael Aponte ,  Thomas Mietzner ,  Dario Massa ,  Thomas Seitz ,  Peter Dombo ,  Andreas Landes ,  Stefan Tresch ,  Trevor William Newton

IPC: A01N43/653 ,  C07D249/12 ,  C07D401/12

Abstract: The present invention relates to phenyltriazolinones of formula (I) or their agriculturally acceptable salts or derivatives, wherein the variables are defined according to the description, processes and intermediates for preparing the uracilpyryidines of the formula (I), compositions comprising them and their use as herbicides, i.e. for controlling harmful plants, and also a method for controlling unwanted vegetation which comprises allowing a herbicidal effective amount of at least one urycilpyridine of the formula (I) to act on plants, their seed and/or their habitat.

公开(公告)号：US10829778B2

公开(公告)日：2020-11-10

申请号：US14787895

申请日：2014-04-28

Applicant: BASF SE

Inventor： Maciej Pasternak ,  Stefan Tresch ,  Helmut Kraus ,  Johannes Hutzler ,  Jens Lerchl ,  Thomas Mietzner ,  Liliana Parra Rapado ,  Jill Marie Paulik

IPC: A01H5/10 ,  C12N15/82 ,  C12N9/02 ,  A01N43/82

Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of: providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type hydroxyphenyl pyruvate dioxygenase or a mutated hydroxyphenyl pyruvate dioxygenase (mut-HPPD) which is resistant or tolerant to a N-heterocyclyl-arylcarboxamide and/or a nucleotide sequence encoding a wild-type homogentisate solanesyl transferase or a mutated homogentisate solanesyl transferase (mut-HST) which is resistant or tolerant to a N-heterocyclyl-arylcarboxamide, and applying to said site an effective amount of said herbicide. The invention further refers to a method of identifying a nucleotide sequence encoding a mut-HPPD which is resistant or tolerant to a N-heterocyclyl-arylcarboxamide, as well as transgenic plants having increased resistance or tolerance to a N-heterocyclyl-arylcarboxamide as compared to a wild-type variety of the plant cell.

公开(公告)号：US20180023060A1

公开(公告)日：2018-01-25

申请号：US15549499

申请日：2016-02-10

Applicant: BASF SE

Inventor： Stefan Tresch ,  Maciej Pasternak ,  Liliana Parra Rapado ,  Jill Paulik ,  Jens Lerchl ,  Gilbert Besong ,  Markus Kordes ,  Thomas Mietzner ,  Eva Stauffer

IPC: C12N9/02 ,  C12N15/82

CPC classification number: C12N9/0069 ,  C12N15/8274

Abstract: The present invention refers to method for producing a transgenic plant with increased herbicide tolerance or resistance as compared to a corresponding non-transformed wild type plant, comprising transforming a plant cell or a plant cell nucleus or a plant tissue with a nucleic acid molecule encoding a mutated HPPD polypeptide, as well as to the nucleic acid, and plants with increased HPPD-inhibiting herbicide tolerance or resistance comprising the nucleic acid of the invention.

公开(公告)号：US09480259B2

公开(公告)日：2016-11-01

申请号：US14405942

申请日：2013-05-29

Applicant: BASF SE

Inventor： Matthias Witschel ,  Frank Stelzer ,  Johannes Hutzler ,  Tao Qu ,  Thomas Mietzner ,  Klaus Kreuz ,  Klaus Grossmann ,  Raphael Aponte ,  Hans Wolfgang Hoeffken ,  Frederick Calo ,  Thomas Ehrhardt ,  Anja Simon ,  Liliana Parra Rapado

IPC: C07D491/052 ,  A01N43/90 ,  C07D311/94 ,  A01N47/20

CPC classification number: A01N43/90 ,  A01N47/20 ,  C07D311/94 ,  C07D491/052

Abstract: The present invention relates to a pyrazolopyran of the general formula I wherein the variables are defined according to the description, including a tautomer, salt, cleavable prodrug, or mixtures thereof, in particular to said pyrazolopyran for use as a medicament and/or an inhibitor of the enzyme serinehydroxymethyltransferase (SHMT). The invention also relates to a process the preparation of a pyrazolopyran of the formula I, to compositions comprising said compound and processes for the preparation of these compositions. Further it relates to use of the pyrazolopyran of formula I as an herbicide as well as to a method of controlling undesired vegetation.

公开(公告)号：US20160102317A1

公开(公告)日：2016-04-14

申请号：US14888025

申请日：2014-04-28

Applicant: BASF SE ,  BASF (CHINA) COMPANY LIMITED

Inventor： Maciej Pasternak ,  Stefan Tresch ,  Helmut Kraus ,  Johannes Hutzler ,  Jens Lerchl ,  Thomas Mietzner ,  Liliana Parra Rapado ,  Jill Marie Paulik

IPC: C12N15/82 ,  A01N43/82 ,  A01N43/713 ,  C12N9/02

CPC classification number: C12N15/8274 ,  A01N43/713 ,  A01N43/82 ,  C12N9/0069 ,  C12N15/821 ,  C12Y113/11027

Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type hydroxyphenyl pyruvate dioxygenase or a mutated hydroxyphenyl pyruvate dioxygenase (mut-HPPD) which is resistant or tolerant to a HPPD-inhibiting herbicide and/or a nucleotide sequence encoding a wild-type homogentisate solanesyl transferase or a mutated homogentisate solanesyl transferase (mut-HST) which is resistant or tolerant to a HPPD-inhibiting herbicide, preferably a bicycloarylcarboxamide, applying to said site an effective amount of said herbicide. The invention further refers to plants comprising mut-HPPD, and methods of obtaining such plants.

Abstract translation: 本发明涉及一种用于在植物培养部位控制不需要的植物的方法，所述方法包括以下步骤：在所述部位提供包含至少一种核酸的植物，所述核酸包含编码野生型羟基苯基丙酮酸双加氧酶的核苷酸序列 或抗HPPD抑制性除草剂具有抗性或耐受性的突变的羟基苯基丙酮酸双加氧酶（mut-HPPD）和/或编码野生型果糖苷转移酶或突变的果糖酸solanesyl转移酶（mut-HST）的核苷酸序列，其抗性 或耐受于HPPD抑制性除草剂，优选二环芳基羧酰胺，向所述位点施用有效量的所述除草剂。 本发明还涉及包含mut-HPPD的植物以及获得这种植物的方法。

公开(公告)号：US20140357487A1

公开(公告)日：2014-12-04

申请号：US14355488

申请日：2012-10-30

Applicant: BASF SE

Inventor： Johannes Hutzler ,  Stefan Tresch ,  Thomas Mietzner ,  Matthias Witschel ,  Jens Lerchl ,  Raphael Aponte ,  Liliana Parra Rapado ,  Jill Marie Paulik

IPC: C12N15/82 ,  A01N43/60 ,  A01N43/40

CPC classification number: C12N15/8274 ,  A01N43/40 ,  A01N43/60 ,  C12N9/0069 ,  C12N9/1085 ,  C12Y113/11027

Abstract: The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type hydroxyphenyl pyruvate dioxygenase or a mutated hydroxyphenyl pyruvate dioxygenase (mut-HPPD) which is resistant or tolerant to a coumarone-derivative herbicide and/or a nucleotide sequence encoding a wild-type homogentisate solanesyl transferase or a mutated homogentisate solanesyl transferase (mut-HST) which is resistant or tolerant to a coumarone-derivative herbicide, and applying to said site an effective amount of said herbicide. The invention further refers to plants comprising mut-HPPD, and methods of obtaining such plants.

Abstract translation: 本发明涉及一种用于在植物培养部位控制不需要的植物的方法，所述方法包括以下步骤：在所述部位提供包含至少一种核酸的植物，所述核酸包含编码野生型羟基苯基丙酮酸双加氧酶的核苷酸序列 或对于香豆酮衍生物除草剂具有抗性或耐受性的突变的羟基苯基丙酮酸双加氧酶（mut-HPPD）和/或编码野生型谷胱甘肽基转移酶的核苷酸序列或抗性的突变的果糖酸solanesyl转移酶（mut-HST） 或对香豆酮衍生物除草剂具有耐受性，并向所述部位施用有效量的所述除草剂。 本发明还涉及包含mut-HPPD的植物以及获得这种植物的方法。