公开(公告)号：US20150126371A1

公开(公告)日：2015-05-07

申请号：US14405942

申请日：2013-05-29

申请人： BASF SE

发明人： Matthias Witschel ,  Frank Stelzer ,  Johannes Hutzler ,  Tao Qu ,  Thomas Mietzner ,  Klaus Kreuz ,  Klaus Grossmann ,  Raphael Aponte ,  Hans Wolfgang Hoeffken ,  Frederick Calo ,  Thomas Ehrhardt ,  Anja Simon ,  Liliana Parra Rapado

IPC分类号： A01N43/90 ,  A01N47/20 ,  C07D491/052

CPC分类号： A01N43/90 ,  A01N47/20 ,  C07D311/94 ,  C07D491/052

摘要： The present invention relates to a pyrazolopyran of the general formula I wherein the variables are defined according to the description, including a tautomer, salt, cleavable prodrug, or mixtures thereof, in particular to said pyrazolopyran for use as a medicament and/or an inhibitor of the enzyme serinehydroxymethyltransferase (SHMT). The invention also relates to a process the preparation of a pyrazolopyran of the formula I, to compositions comprising said compound and processes for the preparation of these compositions. Further it relates to use of the pyrazolopyran of formula I as an herbicide as well as to a method of controlling undesired vegetation.

摘要翻译： 本发明涉及通式I的吡唑并兰，其中根据描述定义变量，包括互变异构体，盐，可切割前药或其混合物，特别是所述吡唑并吡喃用作药物和/或抑制剂 的酶丝氨酸羟甲基转移酶（SHMT）。 本发明还涉及制备式I的吡唑并吡喃的方法，包括所述化合物的组合物和制备这些组合物的方法。 此外，它涉及式I的吡唑并吡喃作除草剂以及控制不希望的植物的方法。

公开(公告)号：US09480259B2

公开(公告)日：2016-11-01

申请号：US14405942

申请日：2013-05-29

申请人： BASF SE

发明人： Matthias Witschel ,  Frank Stelzer ,  Johannes Hutzler ,  Tao Qu ,  Thomas Mietzner ,  Klaus Kreuz ,  Klaus Grossmann ,  Raphael Aponte ,  Hans Wolfgang Hoeffken ,  Frederick Calo ,  Thomas Ehrhardt ,  Anja Simon ,  Liliana Parra Rapado

IPC分类号： C07D491/052 ,  A01N43/90 ,  C07D311/94 ,  A01N47/20

CPC分类号： A01N43/90 ,  A01N47/20 ,  C07D311/94 ,  C07D491/052

摘要： The present invention relates to a pyrazolopyran of the general formula I wherein the variables are defined according to the description, including a tautomer, salt, cleavable prodrug, or mixtures thereof, in particular to said pyrazolopyran for use as a medicament and/or an inhibitor of the enzyme serinehydroxymethyltransferase (SHMT). The invention also relates to a process the preparation of a pyrazolopyran of the formula I, to compositions comprising said compound and processes for the preparation of these compositions. Further it relates to use of the pyrazolopyran of formula I as an herbicide as well as to a method of controlling undesired vegetation.