公开(公告)号：US09968527B2

公开(公告)日：2018-05-15

申请号：US14989022

申请日：2016-01-06

Applicant: Colgate-Palmolive Company

Inventor： James R. Brown ,  Linh Fruge ,  Tao Xu ,  Michael Prencipe

IPC: A61K8/00 ,  A61K8/24 ,  A61K8/36 ,  A61Q11/00 ,  A61K8/21 ,  A61K8/03 ,  A61K8/19 ,  A61K8/20 ,  A61K8/81 ,  A61K8/55 ,  A61K8/69 ,  A61K8/25

CPC classification number: A61K8/21 ,  A61K8/03 ,  A61K8/19 ,  A61K8/20 ,  A61K8/24 ,  A61K8/25 ,  A61K8/55 ,  A61K8/69 ,  A61K8/8164 ,  A61K2800/28 ,  A61K2800/591 ,  A61Q11/00

Abstract: Oral care compositions containing a stannous salt and sodium tripolyphosphate are provided where stannous tripolyphosphate ionic intermediates comprise less than about 1% of the compositions. Tetrasodium pyrophosphate, a methylvinyl ether-maleic anhydride copolymer and/or a silica oral polishing agent may be added for further efficacy. In a single phase blend, the oral care composition may be effectively limited to comprise less than about 10% water. In a dual-phase blend, a mixture having the stannous salt in a first phase and the sodium tripolyphosphate in a second phase may be generated from a dual chamber storage tube (with each phase provided from a separate chamber) immediately prior to dental care usage.

公开(公告)号：US09962322B2

公开(公告)日：2018-05-08

申请号：US15320093

申请日：2014-06-20

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Kavita Vemishetti ,  Linh Fruge ,  Michael Prencipe

IPC: A61K8/19 ,  A61K8/27 ,  A61Q11/00 ,  A61K8/73 ,  A61K8/81 ,  A61K8/21 ,  A61K8/24

CPC classification number: A61K8/19 ,  A61K8/21 ,  A61K8/24 ,  A61K8/27 ,  A61K8/73 ,  A61K8/731 ,  A61K8/8176 ,  A61Q11/00

Abstract: An oral care composition containing a stannous ion source, a zinc ion source, a polyphosphate, and a thickening agent. The thickening agent contains polyvinylpyrrolidone, a polysaccharide gum and carboxymethyl cellulose. The compositions have excellent rheology properties.

公开(公告)号：US08940280B2

公开(公告)日：2015-01-27

申请号：US13905280

申请日：2013-05-30

Applicant: Colgate-Palmolive Company

Inventor： James R. Brown ,  Linh Fruge ,  Tao Xu ,  Michael Prencipe

IPC: A61K8/00 ,  A61K6/00 ,  A61Q11/00 ,  A61K8/55 ,  A61K8/03 ,  A61K8/19 ,  A61K8/20 ,  A61K8/24 ,  A61K8/81 ,  A61K8/69

CPC classification number: A61K8/21 ,  A61K8/03 ,  A61K8/19 ,  A61K8/20 ,  A61K8/24 ,  A61K8/25 ,  A61K8/55 ,  A61K8/69 ,  A61K8/8164 ,  A61K2800/28 ,  A61K2800/591 ,  A61Q11/00

Abstract: Oral care compositions containing a stannous salt and sodium tripolyphosphate are provided where stannous tripolyphosphate ionic intermediates comprise less than about 1% of the compositions Tetrasodium pyrophosphate, a methylvinyl ether-maleic anhydride copolymer and/or a silica oral polishing agent may be added for further efficacy. In a single phase blend, the oral care composition may be effectively limited to comprise less than about 10% water. In a dual-phase blend, a mixture having the stannous salt in a first phase and the sodium tripolyphosphate in a second phase may be generated from a dual chamber storage tube (with each phase provided from a separate chamber) immediately prior to dental care usage.

Abstract translation: 提供含有亚锡盐和三聚磷酸钠的口腔护理组合物，其中三聚磷酸三钠离子中间体包含少于组合物的约1％焦磷酸四钠，甲基乙烯基醚 - 马来酸酐共聚物和/或二氧化硅口服抛光剂可用于进一步的功效 。 在单相共混物中，口腔护理组合物可以有效地限制为包含小于约10％的水。 在双相共混物中，可以在牙科保健使用之前立即从双室储存管（每个阶段由独立的室提供）产生具有第一相中的亚锡盐和第二相中的三聚磷酸钠的混合物 。