公开(公告)号：US10154948B2

公开(公告)日：2018-12-18

申请号：US15319636

申请日：2014-06-20

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Kavita Vemishetti ,  Linh Fruge ,  Michael Prencipe

IPC: A61K8/27 ,  A61K8/365 ,  A61K8/24 ,  A61K8/21 ,  A61Q11/00 ,  A61K8/19

Abstract: An oral care composition containing a source of stannous ions, a source of fluoride ions and an insoluble source of zinc ions, such as zinc oxide. The composition contains an amount of citric acid sufficient to increase the level of soluble zinc ions.

公开(公告)号：US10792231B2

公开(公告)日：2020-10-06

申请号：US16515182

申请日：2019-07-18

Applicant: Colgate-Palmolive Company

Inventor： Kavita Vemishetti ,  Linh Fruge ,  Michael Prencipe

IPC: A61K8/24 ,  A61K8/27 ,  A61Q11/00 ,  A61K8/21 ,  A61K8/36 ,  A61K8/19

Abstract: The present disclosure provides low water dentifrice compositions comprising an effective amount of a zinc ion source, a stannous ion source, a polyphosphate and an acid in a calcium pyrophosphate base. The acid lowers the pH of the composition to enable stabilization of the metal ions and extend shelf-life of the composition.

公开(公告)号：US20180147125A1

公开(公告)日：2018-05-31

申请号：US15570430

申请日：2015-05-01

Applicant: Colgate-Palmolive Company

Inventor： Kavita Vemishetti ,  Linh FRUGE ,  Michael PRENCIPE

IPC: A61K8/24 ,  A61Q11/00 ,  A61K8/19 ,  A61K8/27 ,  A61K8/21

CPC classification number: A61K8/24 ,  A61K8/19 ,  A61K8/21 ,  A61K8/27 ,  A61K8/36 ,  A61K2800/28 ,  A61K2800/30 ,  A61K2800/31 ,  A61K2800/5922 ,  A61Q11/00

Abstract: The present disclosure provides low water dentifrice compositions comprising an effective amount of a zinc ion source, a stannous ion source, a polyphosphate and an acid in a calcium pyrophosphate base. The acid lowers the pH of the composition to enable stabilization of the metal ions and extend shelf-life of the composition.

公开(公告)号：US10391044B2

公开(公告)日：2019-08-27

申请号：US15570430

申请日：2015-05-01

Applicant: Colgate-Palmolive Company

Inventor： Kavita Vemishetti ,  Linh Fruge ,  Michael Prencipe

IPC: A61K8/24 ,  A61K8/27 ,  A61K8/36 ,  A61Q11/00 ,  A61K8/21 ,  A61K8/19

Abstract: The present disclosure provides low water dentifrice compositions comprising an effective amount of a zinc ion source, a stannous ion source, a polyphosphate and an acid in a calcium pyrophosphate base. The acid lowers the pH of the composition to enable stabilization of the metal ions and extend shelf-life of the composition.

公开(公告)号：US20190142716A1

公开(公告)日：2019-05-16

申请号：US16246821

申请日：2019-01-14

Applicant: Colgate-Palmolive Company

Inventor： Kavita Vemishetti ,  Linh Fruge ,  Michael Prencipe

IPC: A61K8/19 ,  A61K8/24 ,  A61K8/21 ,  A61K8/81 ,  A61K8/27 ,  A61K8/73 ,  A61Q11/00

Abstract: An oral care composition containing a stannous ion source, a zinc ion source, a polyphosphate, and a thickening agent. The thickening agent contains polyvinylpyrrolidone, a polysaccharide gum and carboxymethyl cellulose. The compositions have excellent rheology properties.

公开(公告)号：US11253444B2

公开(公告)日：2022-02-22

申请号：US16309402

申请日：2016-06-24

Applicant: Colgate-Palmolive Company

Inventor： Nihal Dogu ,  Kavita Vemishetti

IPC: A61K8/21 ,  A61K8/24 ,  A61Q11/00 ,  A61K8/34 ,  A61K8/19 ,  A61K8/27 ,  A61K8/362 ,  A61K8/365

Abstract: The present invention relates to an oral care composition for use in the treatment or prevention of erosive tooth demineralization, plaque, and caries. This oral care composition includes zinc lactate dihydrate, a stannous ion source, at least one phosphate salt, and a buffer system.

公开(公告)号：US11135144B2

公开(公告)日：2021-10-05

申请号：US15538285

申请日：2014-12-26

Applicant: Colgate-Palmolive Company

Inventor： Kavita Vemishetti ,  Linh Fruge ,  Michael Prencipe

IPC: A61Q11/00 ,  A61K8/21 ,  A61K8/27 ,  A61K8/24

Abstract: The present disclosure provides low water dentifrice compositions comprising an effective amount of a zinc ion source, a tin ion source, a polyphosphate and an acid. The acid lowers the pH of the composition to enable stabilization of the metal ions and extend shelf-life of the composition.

公开(公告)号：US10213369B2

公开(公告)日：2019-02-26

申请号：US15948654

申请日：2018-04-09

Applicant: Colgate-Palmolive Company

Inventor： Kavita Vemishetti ,  Linh Fruge ,  Michael Prencipe

IPC: A61K8/19 ,  A61K8/27 ,  A61Q11/00 ,  A61K8/73 ,  A61K8/81 ,  A61K8/21 ,  A61K8/24

Abstract: An oral care composition containing a stannous ion source, a zinc ion source, a polyphosphate, and a thickening agent. The thickening agent contains polyvinylpyrrolidone, a polysaccharide gum and carboxymethyl cellulose. The compositions have excellent rheology properties.

公开(公告)号：US20180221257A1

公开(公告)日：2018-08-09

申请号：US15948654

申请日：2018-04-09

Applicant: Colgate-Palmolive Company

Inventor： Kavita Vemishetti ,  Linh Fruge ,  Michael Prencipe

IPC: A61K8/19 ,  A61K8/27 ,  A61K8/81 ,  A61K8/21 ,  A61K8/24 ,  A61Q11/00 ,  A61K8/73

CPC classification number: A61K8/19 ,  A61K8/21 ,  A61K8/24 ,  A61K8/27 ,  A61K8/73 ,  A61K8/731 ,  A61K8/8176 ,  A61Q11/00

Abstract: An oral care composition containing a stannous ion source, a zinc ion source, a polyphosphate, and a thickening agent. The thickening agent contains polyvinylpyrrolidone, a polysaccharide gum and carboxymethyl cellulose. The compositions have excellent rheology properties.

公开(公告)号：US09962322B2

公开(公告)日：2018-05-08

申请号：US15320093

申请日：2014-06-20

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Kavita Vemishetti ,  Linh Fruge ,  Michael Prencipe

IPC: A61K8/19 ,  A61K8/27 ,  A61Q11/00 ,  A61K8/73 ,  A61K8/81 ,  A61K8/21 ,  A61K8/24

CPC classification number: A61K8/19 ,  A61K8/21 ,  A61K8/24 ,  A61K8/27 ,  A61K8/73 ,  A61K8/731 ,  A61K8/8176 ,  A61Q11/00

Abstract: An oral care composition containing a stannous ion source, a zinc ion source, a polyphosphate, and a thickening agent. The thickening agent contains polyvinylpyrrolidone, a polysaccharide gum and carboxymethyl cellulose. The compositions have excellent rheology properties.