公开(公告)号：US20200206116A1

公开(公告)日：2020-07-02

申请号：US16815106

申请日：2020-03-11

Applicant: Colgate-Palmolive Company

Inventor： Michael PRENCIPE ,  Amy RUSSO ,  Hansruedi STETTLER ,  Betty WON ,  Lisa MANUS ,  Michael STRANICK ,  Peng YAN ,  Chengkang TAN ,  Vyoma PATEL ,  André MORGAN ,  Andrei POTANIN ,  Xiao Yi HUANG

IPC: A61K8/44 ,  A61K8/365 ,  A61K8/34 ,  A61K8/25 ,  A61K8/37 ,  A61K8/04 ,  A61K8/21 ,  A61K8/73 ,  A61Q11/00 ,  A61K8/27 ,  A61K8/24

Abstract: This invention relates to oral care compositions comprising arginine or lysine, zinc citrate and zinc oxide, fluoride source, and a silica abrasive which exhibits an acid pH when measured as an aqueous slurry as well as to methods of using and of making these compositions.

公开(公告)号：US20190192395A1

公开(公告)日：2019-06-27

申请号：US16291526

申请日：2019-03-04

Applicant: Colgate-Palmolive Company

Inventor： Aarti REGE ,  Michael PRENCIPE ,  Madhuleena BHADRA

IPC: A61K8/27 ,  A61Q11/00 ,  A61K8/36 ,  A61K8/21 ,  A61K8/24

Abstract: An oral care composition comprising zinc phosphate, stannous fluoride and an organic acid buffer system, as well as methods of using the same.

公开(公告)号：US20190105252A1

公开(公告)日：2019-04-11

申请号：US16212129

申请日：2018-12-06

Applicant: Colgate-Palmolive Company

Inventor： Aarti REGE ,  Michael PRENCIPE ,  Marc ESTRIPLET

IPC: A61K8/44 ,  A61Q11/00 ,  A61K8/27 ,  A61K8/21 ,  A61K8/362 ,  A61K8/24 ,  A61K8/365

CPC classification number: A61K8/44 ,  A61K8/21 ,  A61K8/24 ,  A61K8/27 ,  A61K8/362 ,  A61K8/365 ,  A61Q11/00

Abstract: An oral care composition comprising zinc phosphate, stannous fluoride, arginine or lysine and an organic acid buffer system, as well as methods of using the same.

公开(公告)号：US20180235853A1

公开(公告)日：2018-08-23

申请号：US15961949

申请日：2018-04-25

Applicant: Colgate-Palmolive Company

Inventor： James R. BROWN ,  Linh FRUGE ,  Tao XU ,  Michael PRENCIPE

IPC: A61K8/21 ,  A61K8/25 ,  A61K8/03 ,  A61K8/19 ,  A61K8/20 ,  A61K8/24 ,  A61K8/55 ,  A61K8/69 ,  A61K8/81 ,  A61Q11/00

CPC classification number: A61K8/21 ,  A61K8/03 ,  A61K8/19 ,  A61K8/20 ,  A61K8/24 ,  A61K8/25 ,  A61K8/55 ,  A61K8/69 ,  A61K8/8164 ,  A61K2800/28 ,  A61K2800/591 ,  A61Q11/00

Abstract: Oral care compositions containing a stannous salt and sodium tripolyphosphate are provided where stannous tripolyphosphate ionic intermediates comprise less than about 1% of the compositions. Tetrasodium pyrophosphate, a methylvinyl ether-maleic anhydride copolymer and/or a silica oral polishing agent may be added for further efficacy. In a single phase blend, the oral care composition may be effectively limited to comprise less than about 10% water. In a dual-phase blend, a mixture having the stannous salt in a first phase and the sodium tripolyphosphate in a second phase may be generated from a dual chamber storage tube (with each phase provided from a separate chamber) immediately prior to dental care usage.

公开(公告)号：US20160338921A1

公开(公告)日：2016-11-24

申请号：US15106457

申请日：2014-12-10

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Michael PRENCIPE ,  Yun XU ,  Xiao Yi HUANG

IPC: A61K8/27 ,  A61K8/43

CPC classification number: A61K8/27 ,  A61K8/43 ,  A61K8/44 ,  A61K2800/51 ,  A61Q11/00

Abstract: An oral care composition comprising: (a) arginine, in free or salt form; and (b) zinc oxide and zinc citrate. The oral care composition can reduce or inhibit biofilm formation in an oral cavity.

Abstract translation: 一种口腔护理组合物，其包含：（a）游离或盐形式的精氨酸; 和（b）氧化锌和柠檬酸锌。 口腔护理组合物可以减少或抑制口腔中的生物膜形成。

公开(公告)号：US20160030330A1

公开(公告)日：2016-02-04

申请号：US14781907

申请日：2013-05-13

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Andre MORGAN ,  Vyoma PATEL ,  Marilou JOZIAK ,  Michael PRENCIPE

IPC: A61K8/96 ,  A61K8/02 ,  A61K8/44 ,  A61K8/21 ,  A61Q11/00 ,  A61K8/19

CPC classification number: A61K8/965 ,  A61K8/0204 ,  A61K8/0241 ,  A61K8/19 ,  A61K8/21 ,  A61K8/44 ,  A61K2800/28 ,  A61K2800/41 ,  A61K2800/412 ,  A61K2800/592 ,  A61Q11/00

Abstract: Disclosed are oral care compositions comprising an abrasive system, wherein the abrasive system comprises (a) a first particulate abrasive comprising at least 20 wt % pumice, based on the weight of the oral care composition, having an average particle size of from 20 to 300 microns; and (b) a second particulate abrasive comprising calcium carbonate having an average particle size of from 2 to 13 microns. There is also disclosed a method of cleaning teeth comprising applying the oral care composition to a tooth surface, the oral care composition being applied as a paste disposed in a prophy cup.

Abstract translation: 公开了包含磨料体系的口腔护理组合物，其中磨料体系包含（a）基于口腔护理组合物的重量，包含至少20重量％浮石的平均粒度为20至300的第一颗粒磨料 微米 和（b）包含平均粒径为2至13微米的碳酸钙的第二颗粒磨料。 还公开了一种清洁牙齿的方法，包括将口腔护理组合物施用于牙齿表面，所述口腔护理组合物作为糊状物施用，设置在植物杯中。

公开(公告)号：US20150258005A1

公开(公告)日：2015-09-17

申请号：US14723139

申请日：2015-05-27

Applicant: Colgate-Palmolive Company

Inventor： Lynette A. ZAIDEL ,  Guisheng PAN ,  Suman K. CHOPRA ,  Prakasarao MANDADI ,  Michael PRENCIPE

IPC: A61K8/81 ,  A61Q11/00 ,  A61K8/24 ,  A61K8/22 ,  A61K8/90

CPC classification number: A61K8/8176 ,  A61K8/0208 ,  A61K8/22 ,  A61K8/24 ,  A61K8/49 ,  A61K8/817 ,  A61K8/891 ,  A61K8/90 ,  A61K2800/805 ,  A61Q11/00 ,  A61Q11/02

Abstract: Oral care compositions comprising: (a) a peroxide complex comprising a peroxide component and an N-vinyl heterocyclic polymer (e.g., poly-N-vinyl polylactam, or poly-N-vinyl-polyimide); (b) a whitening agent (e.g., hydrogen peroxide); and (c) an orally acceptable carrier. In one embodiment, the carrier comprises a film forming material. Methods are also provided for making an oral care composition comprising: (a) mixing a whitening agent, silicone adhesive and carrier fluid to form a homogenous mixture; (b) adding a peroxide complex to said homogenous mixture, wherein said complex comprises hydrogen peroxide and an N-vinyl heterocyclic polymer; and (c) mixing under vacuum.

Abstract translation: 口腔护理组合物，其包含：（a）包含过氧化物组分和N-乙烯基杂环聚合物（例如聚-N-乙烯基聚内酰胺或聚-N-乙烯基 - 聚酰亚胺）的过氧化物络合物; （b）增白剂（例如过氧化氢）; 和（c）口头可接受的承运人。 在一个实施方案中，载体包括成膜材料。 还提供了用于制备口腔护理组合物的方法，其包括：（a）将增白剂，硅氧烷粘合剂和载体流体混合以形成均匀的混合物; （b）向所述均匀混合物中加入过氧化物络合物，其中所述络合物包含过氧化氢和N-乙烯基杂环聚合物; 和（c）在真空下混合。

公开(公告)号：US20240074955A1

公开(公告)日：2024-03-07

申请号：US18508746

申请日：2023-11-14

Applicant: Colgate-Palmolive Company

Inventor： Aarti REGE ,  Michael PRENCIPE ,  Paul THOMSON ,  Rehana BEGUM-GAFUR

IPC: A61K8/24 ,  A61K8/20 ,  A61K8/21 ,  A61K8/27 ,  A61Q11/00

CPC classification number: A61K8/24 ,  A61K8/20 ,  A61K8/21 ,  A61K8/27 ,  A61Q11/00

Abstract: This invention relates to oral care compositions comprising zinc phosphate, a first source of stannous (e.g., stannous fluoride); and a second source of stannous, wherein the second source of stannous comprises stannous pyrophosphate, as well as to methods of using and of making these compositions.

公开(公告)号：US20230218494A1

公开(公告)日：2023-07-13

申请号：US18180717

申请日：2023-03-08

Applicant: Colgate-Palmolive Company

Inventor： Michael PRENCIPE ,  Amy Russo ,  Hansruedi Stettler ,  André Morgan

IPC: A61K8/44 ,  A61K8/25 ,  A61K8/27 ,  A61K8/34 ,  A61K8/21 ,  A61K8/365 ,  A61K8/362 ,  A61Q11/00

CPC classification number: A61K8/44 ,  A61K8/25 ,  A61K8/27 ,  A61K8/345 ,  A61K8/21 ,  A61K8/365 ,  A61K8/362 ,  A61Q11/00 ,  A61K2800/28 ,  A61K2800/92

Abstract: This invention relates to oral care compositions comprising arginine or lysine, zinc citrate and zinc oxide, and a fluoride source, as well as to methods of using and of making these compositions.

公开(公告)号：US20220241161A1

公开(公告)日：2022-08-04

申请号：US17725204

申请日：2022-04-20

Applicant: Colgate-Palmolive Company

Inventor： Aarti REGE ,  Michael PRENCIPE

IPC: A61K8/27 ,  A61K8/36 ,  A61K6/20 ,  A61K8/21 ,  A61K8/24 ,  A61K8/81 ,  A61Q11/00

Abstract: An oral care composition comprising zinc phosphate, stannous fluoride and an organic acid buffer system, as well as methods of using the same.