公开(公告)号：US20150328094A1

公开(公告)日：2015-11-19

申请号：US14654511

申请日：2012-12-24

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Yun Xu ,  Xiao Yi Huang ,  Yuan Hui Xie ,  Xiong Fei Qin

IPC: A61K8/25 ,  A61K8/365 ,  A61K8/27 ,  A61Q11/00 ,  A61K8/19

CPC classification number: A61K8/19 ,  A61K8/25 ,  A61K8/27 ,  A61K8/365 ,  A61K2800/28 ,  A61K2800/592 ,  A61Q11/00

Abstract: The present invention relates to a tooth whitening oral care composition, the use of abrasives in such an oral care composition, a method of polishing tooth enamel, and an oral care kit comprising the oral care composition.

Abstract translation: 本发明涉及牙齿美白口腔护理组合物，在这种口腔护理组合物中使用研磨剂，抛光牙釉质的方法和包含口腔护理组合物的口腔护理套件。

公开(公告)号：US12220473B2

公开(公告)日：2025-02-11

申请号：US18165398

申请日：2023-02-07

Applicant: Colgate-Palmolive Company

Inventor： Yun Xu ,  Stacey Lavender ,  Luciana Rinaudi Marron ,  Zoe Scoullos ,  Manish Mandhare

IPC: A61K8/44 ,  A61K8/24 ,  A61Q11/00

Abstract: This invention relates to oral care compositions, for example comprising a salt of a basic amino acid having a pH in solution of less than 7.5, an abrasive having a pH in solution of less than 7.5, and a fluoride ion source, and an acid selected from the group consisting of: a carboxylic acid (e.g., citric acid, lactic acid, glycolic acid, acetic acid, succinic acid, or fumaric acid), and an inorganic acid, wherein the inorganic acid is not phosphoric acid or sulfuric acid (e.g., wherein the inorganic acid is hydrochloric acid or sodium acid pyrophosphate), and to methods of using and of making these compositions.

公开(公告)号：US20240277592A1

公开(公告)日：2024-08-22

申请号：US18635785

申请日：2024-04-15

Applicant: Colgate-Palmolive Company

Inventor： Aradhana Das ,  Hongwei Shen ,  Eric Simon ,  Yun Xu

IPC: A61K8/46 ,  A61K8/19 ,  A61K8/44 ,  A61K8/60 ,  A61Q11/00

CPC classification number: A61K8/466 ,  A61K8/19 ,  A61K8/44 ,  A61K8/604 ,  A61Q11/00 ,  A61K2800/28 ,  A61K2800/30 ,  A61K2800/596 ,  A61K2800/92

Abstract: This invention relates to oral care compositions with improved foaming properties which comprise a basic amino acid, an abrasive and a taurate surfactant, as well as to methods of using these compositions. Optionally, the oral care compositions further comprise an alkyl polyglucoside.

公开(公告)号：US11918675B2

公开(公告)日：2024-03-05

申请号：US17247099

申请日：2020-11-30

Applicant: Colgate-Palmolive Company

Inventor： Salima Hammadi ,  Harsh Mahendra Trivedi ,  Melissa Martinetti ,  David Suriano ,  Michael Fitzgerald ,  Yun Xu ,  Shashank Potnis ,  Karthik Sambanthamoorthy

IPC: A61K8/73 ,  A61K8/21 ,  A61K8/27 ,  A61K8/34

CPC classification number: A61K8/73 ,  A61K8/21 ,  A61K8/27 ,  A61K8/345 ,  A61K2800/48

Abstract: Described herein are oral care compositions comprising—in relevant part—an effective amount of inulin. Methods of making and using these compositions are also described.

公开(公告)号：US10555880B2

公开(公告)日：2020-02-11

申请号：US16062163

申请日：2015-12-18

Applicant: Colgate-Palmolive Company

Inventor： Manying Shi ,  Yun Xu ,  Xiaojing Lu ,  Yuan Wu

IPC: A61K6/00 ,  A61K8/27 ,  A61Q11/00 ,  A61K8/73 ,  A61K8/362

Abstract: Disclosed is a method of making a sodium zinc alginate structurant that can include combining a sodium alginate, a zinc compound, and a liquid media, and mixing to a desired viscosity. Further disclosed is a method of making an oral care composition that can include combining a sodium zinc alginate structurant with one or more agents, and mixing.

公开(公告)号：US10441517B2

公开(公告)日：2019-10-15

申请号：US15106457

申请日：2014-12-10

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Michael Prencipe ,  Yun Xu ,  Xiao Yi Huang

IPC: A61K8/02 ,  A61K8/27 ,  A61Q11/00 ,  A61K8/43 ,  A61K8/36 ,  A61K8/44

Abstract: An oral care composition comprising: (a) arginine, in free or salt form; and (b) zinc oxide and zinc citrate. The oral care composition can reduce or inhibit biofilm formation in an oral cavity.

公开(公告)号：US20180304102A1

公开(公告)日：2018-10-25

申请号：US15523777

申请日：2014-11-14

Applicant: Colgate-Palmolive Company

Inventor： Yan Gao ,  Zhaoyu Wen ,  Guangxin Lin ,  Yun Xu ,  Zhiping Zhong

IPC: A61Q11/00 ,  A61K8/25 ,  G01N33/15

Abstract: Disclosed herein are methods for evaluating the whitening effect of oral care composition on a stained egg comprising staining an eggshell, applying the oral care composition to a portion of the stained eggshell to obtain a treated eggshell area, calculating a ΔE value for the difference in color of the treated eggshell area compared to untreated stained eggshell when calculated in L*a*b color space, wherein the oral care composition comprises at least one high cleaning silica for stain removal. Further disclosed herein are methods for demonstrating the whitening effect of an oral care composition on a stained egg comprising showing an egg that has been stained to at least one consumer and brushing an oral care composition comprising at least one high cleaning silica for stain removal on a portion of the stained eggshell to obtain a treated eggshell area.

公开(公告)号：US10071032B2

公开(公告)日：2018-09-11

申请号：US15529243

申请日：2014-12-15

Applicant: Colgate-Palmolive Company

Inventor： Yun Xu ,  Dorathy Zeng ,  Kahn Tan ,  Pingdong Li

IPC: A61K8/21 ,  A61K8/27 ,  A61Q11/00 ,  A61K8/19 ,  A61K8/20 ,  A61K8/24 ,  A61K8/25 ,  A61K8/365 ,  A61K8/60 ,  A61K8/86

CPC classification number: A61K8/27 ,  A61K8/19 ,  A61K8/20 ,  A61K8/24 ,  A61K8/25 ,  A61K8/365 ,  A61K8/60 ,  A61K8/86 ,  A61K2800/48 ,  A61Q11/00

Abstract: Compositions and methods of treating and/or preventing conditions of the oral cavity, e.g. gingivitis, comprise applying a toothpaste composition comprising at least 5% sodium chloride in a toothpaste base comprising a zinc salt, non-silica calcium carbonate abrasive and humectant, to the oral surfaces, e.g., the teeth and gums, of a patient in need thereof.

公开(公告)号：US09968528B2

公开(公告)日：2018-05-15

申请号：US14653214

申请日：2012-12-18

Applicant: Colgate-Palmolive Company

Inventor： Yun Xu ,  Xiaoyi Huang ,  Yuanhui Xie ,  Xiongfei Qin

IPC: A61K8/24 ,  A61K8/365 ,  A61K8/27 ,  A61Q11/00 ,  A61K8/73

CPC classification number: A61K8/24 ,  A61K8/27 ,  A61K8/365 ,  A61K8/73 ,  A61K8/731 ,  A61K2800/48 ,  A61Q11/00

Abstract: Disclosed herein are oral care compositions comprising: a) one or more pyrophosphate compounds, wherein the total concentration of pyrophosphate compounds in the composition is 0.5 wt % to 1.5 wt %, based on the weight of the oral care composition; b) one or more thickening gums, wherein the total concentration of thickening gums in the composition is 1.25 wt % to 1.6 wt %, based on the weight of the oral care composition; and c) a metal ion source.

公开(公告)号：US20170035663A1

公开(公告)日：2017-02-09

申请号：US15102537

申请日：2013-12-11

Applicant: Colgate-Palmolive Company

Inventor： Yuyan Zeng ,  Chengkang Tan ,  Pingdong Li ,  Yun Xu

IPC: A61K8/19 ,  A61K8/34 ,  A61K8/86 ,  A61K8/25 ,  A61K8/60 ,  A61K8/46 ,  A61K8/73 ,  A61Q11/00 ,  A61K8/24

CPC classification number: A61K8/19 ,  A61K8/20 ,  A61K8/21 ,  A61K8/24 ,  A61K8/25 ,  A61K8/345 ,  A61K8/463 ,  A61K8/60 ,  A61K8/731 ,  A61K8/86 ,  A61K2800/28 ,  A61K2800/48 ,  A61Q11/00

Abstract: A method of treating gingivitis comprises applying a toothpaste comprising at least 5% sodium chloride in a toothpaste base comprising a non-silica calcium carbonate abrasive and humectant, to the oral surfaces, e.g., the teeth and gums, of a patient in need thereof, together with compositions for use therefor.

Abstract translation: 一种治疗牙龈炎的方法包括将包含至少5％氯化钠的牙膏施加到包含非二氧化硅碳酸钙研磨剂和湿润剂的牙膏基质中，所述口腔表面例如有需要的患者的牙齿和牙龈， 以及用于其的组合物。