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21.发明申请Analogues of lipid mediators derived from omega-3 PUFAs and methods of use 有权衍生自ω-3 PUFA的脂质介体的类似物和使用方法公开(公告)号：US20080207753A1
公开(公告)日：2008-08-28
申请号：US12150794
申请日：2008-04-30
CPC分类号： C07C59/68 , C07C59/42 , C07C59/48 , C07C59/64 , C07C69/732 , C07C69/736 , C07C235/28 , C07C235/34
摘要： The present invention is directed to compounds that are analogues of lipid mediators derived from a fish oil-derived fatty acid, eicosapentaenoic acid [C20:5 ω-3; EPA], but with a longer tissue half-life and enhanced bioactivity. These analogues may be used to treat inflammatory, angioproliferative, cardiovascular, thrombophlebotic, vascular, ocular, dermatologic, neurodegenerative, pulmonary, endocrine, reproductive, rheumatologic and gastrointestinal diseases.
摘要翻译： 本发明涉及衍生自鱼油衍生的脂肪酸，二十碳五烯酸[C20：5ω-3; EPA]，但具有更长的组织半衰期和增强的生物活性。 这些类似物可用于治疗炎症，血管增生，心血管，血栓形成，血管，眼，皮肤病，神经变性，肺，内分泌，生殖，风湿病和胃肠道疾病。
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公开(公告)号：US20130035294A1
公开(公告)日：2013-02-07
申请号：US13651130
申请日：2012-10-12
CPC分类号： A61K38/22
摘要： Methods and compositions for treating psychiatric diseases and disorders are disclosed. The methods provided generally involve the administration of an NMX peptide, an FNX peptide, or an NMX receptor agonist, or analogs or derivatives thereof, to a subject in order to treat psychiatric diseases and disorders, and conditions associated with psychiatric diseases and disorders.
摘要翻译： 公开了治疗精神疾病和病症的方法和组合物。 所提供的方法通常涉及向受试者施用NMX肽，FNX肽或NMX受体激动剂或其类似物或衍生物，以治疗精神疾病和病症，以及与精神疾病和病症相关的病症。
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23.发明授权Amylin agonist for treating depression, anxiety disorder and schizophrenia 失效用于治疗抑郁症，焦虑障碍和精神分裂症的胰岛淀粉样多肽激动剂公开(公告)号：US07671023B2
公开(公告)日：2010-03-02
申请号：US11910206
申请日：2006-03-31
摘要： Methods and compositions for treating psychiatric diseases and disorders are disclosed. The methods provided generally involve the administration of an amylin or an amylin agonist to a subject in order to treat psychiatric diseases and disorders, and conditions associated with psychiatric diseases and disorders.
摘要翻译： 公开了治疗精神疾病和病症的方法和组合物。 提供的方法通常涉及对受试者施用胰岛淀粉样多肽或胰岛淀粉样多肽激动剂以治疗精神疾病和病症，以及与精神疾病和病症相关的病症。
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公开(公告)号：US07378444B2
公开(公告)日：2008-05-27
申请号：US10460913
申请日：2003-06-13
IPC分类号： A61K31/22 , A61K31/20 , A61K31/16 , C07C231/00 , C07C59/00
CPC分类号： C07C59/68 , C07C59/42 , C07C59/48 , C07C59/64 , C07C69/732 , C07C69/736 , C07C235/28 , C07C235/34
摘要： The present invention is directed to compounds that are analogues of lipid mediators derived from a fish oil-derived fatty acid, eicosapentaenoic acid [C20:5 ω-3; EPA], but with a longer tissue half-life and enhanced bioactivity. These analogues may be used to treat inflammatory, angioproliferative, cardiovascular, thrombophlebotic, vascular, ocular, dermatologic, neurodegenerative, pulmonary, endocrine, reproductive, rheumatologic and gastrointestinal diseases.
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公开(公告)号：US20130184213A1
公开(公告)日：2013-07-18
申请号：US13777149
申请日：2013-02-26
摘要： Methods and compositions for treating psychiatric diseases and disorders are disclosed. The methods provided generally involve the administration of an amylin or an amylin agonist to a subject in order to treat psychiatric diseases and disorders, and conditions associated with psychiatric diseases and disorders.
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26.发明授权Amylin and amylin agonists for treating psychiatric diseases and disorders 失效胰岛淀粉样多肽和胰岛淀粉样多肽激动剂用于治疗精神疾病和病症公开(公告)号：US08389477B2
公开(公告)日：2013-03-05
申请号：US13112290
申请日：2011-05-20
摘要： Methods and compositions for treating psychiatric diseases and disorders are disclosed. The methods provided generally involve the administration of an amylin or an amylin agonist to a subject in order to treat psychiatric diseases and disorders, and conditions associated with psychiatric diseases and disorders.
摘要翻译： 公开了治疗精神疾病和病症的方法和组合物。 提供的方法通常涉及对受试者施用胰岛淀粉样多肽或胰岛淀粉样多肽激动剂以治疗精神疾病和病症，以及与精神疾病和病症相关的病症。
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公开(公告)号：US08309522B2
公开(公告)日：2012-11-13
申请号：US12524903
申请日：2008-02-04
IPC分类号： A61K38/00
CPC分类号： A61K38/22
摘要： Methods and compositions for treating psychiatric diseases and disorders are disclosed. The methods provided generally involve the administration of an NMX peptide, an FNX peptide, or an NMX receptor agonist, or analogs or derivatives thereof, to a subject in order to treat psychiatric diseases and disorders, and conditions associated with psychiatric diseases and disorders.
摘要翻译： 公开了治疗精神疾病和病症的方法和组合物。 所提供的方法通常涉及向受试者施用NMX肽，FNX肽或NMX受体激动剂或其类似物或衍生物，以治疗精神疾病和病症，以及与精神疾病和病症相关的病症。
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公开(公告)号：US20100168013A1
公开(公告)日：2010-07-01
申请号：US12524903
申请日：2008-02-04
CPC分类号： A61K38/22
摘要： Methods and compositions for treating psychiatric diseases and disorders are disclosed. The methods provided generally involve the administration of an NMX peptide, an FNX peptide, or an NMX receptor agonist, or analogs or derivatives thereof, to a subject in order to treat psychiatric diseases and disorders, and conditions associated with psychiatric diseases and disorders.
摘要翻译： 公开了治疗精神疾病和病症的方法和组合物。 所提供的方法通常涉及向受试者施用NMX肽，FNX肽或NMX受体激动剂或其类似物或衍生物，以治疗精神疾病和病症，以及与精神疾病和病症相关的病症。
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29.发明申请Amylin and Amylin Agonists For Treating Psychiatric Diseases and Disorders 失效胰岛淀粉样多肽和胰岛淀粉样变性激素治疗精神疾病和疾病公开(公告)号：US20080287355A1
公开(公告)日：2008-11-20
申请号：US11910206
申请日：2006-03-31
摘要： Methods and compositions for treating psychiatric diseases and disorders are disclosed. The methods provided generally involve the administration of an amylin or an amylin agonist to a subject in order to treat psychiatric diseases and disorders, and conditions associated with psychiatric diseases and disorders.
摘要翻译： 公开了治疗精神疾病和病症的方法和组合物。 提供的方法通常涉及对受试者施用胰岛淀粉样多肽或胰岛淀粉样多肽激动剂以治疗精神疾病和病症，以及与精神疾病和病症相关的病症。
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