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公开(公告)号:US20090088377A1
公开(公告)日:2009-04-02
申请号:US12122627
申请日:2008-05-16
CPC分类号: C07K14/005 , A61K38/00 , C12N2740/16122 , Y02A50/463
摘要: This invention relates to C34 peptide derivatives having improved aqueous solubility that are inhibitors of viral infection and/or exhibit antifusogenic properties. In particular, this invention relates to C34 derivatives having inhibiting activity against human immunodeficiency virus (HIV), respiratory synctial virus (RSV), human parainfluenza virus (HPV), measles virus (MeV), and simian immunodeficiency virus (SIV) with long duration of action for the treatment of the respective viral infections.
摘要翻译: 本发明涉及具有改善的水溶性的C34肽衍生物,其是病毒感染的抑制剂和/或表现出抗融合性质。 特别地,本发明涉及具有长期持续时间的针对人类免疫缺陷病毒(HIV),呼吸道合胞病毒(RSV),人副流感病毒(HPV),麻疹病毒(MeV)和猿猴免疫缺陷病毒(SIV))的抑制活性的C34衍生物 的治疗各自病毒感染的作用。
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公开(公告)号:US20100000686A1
公开(公告)日:2010-01-07
申请号:US12166947
申请日:2008-07-02
申请人: Martin Robitaille , Steve Gagnon
发明人: Martin Robitaille , Steve Gagnon
CPC分类号: B65H59/04 , B65H2701/37 , B65H2701/375
摘要: The present invention discloses a roll holder for tape dispenser and a tape dispenser assembly therewith. The roll holder comprises a cylindrical body and an annular portion made from a material having a high friction coefficient, the annular portion being fixed inside the cylindrical body. The roll holder tape dispenser is supported by a shaft. Two cylindrical bodies are connected to a roll of tape, one at each extremity of the tape spool by press-fitting. The shaft passes through the annular portion and the friction occurring between the shaft and annular portion induce a tension in the tape when the tape is unwound from the roll.
摘要翻译: 本发明公开了一种用于胶带分配器的卷筒保持器和一个带分配器组件。 辊保持器包括圆筒体和由具有高摩擦系数的材料制成的环形部分,环形部分固定在圆柱体内。 卷筒胶带分配器由轴支撑。 两个圆柱体连接到一卷胶带,一个通过压配合在带卷轴的每个末端。 轴通过环形部分,并且当带从卷上展开时,在轴和环形部分之间产生的摩擦引起带中的张力。
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公开(公告)号:US20050176641A1
公开(公告)日:2005-08-11
申请号:US11040810
申请日:2005-01-21
申请人: Peter Bakis , Dominique Bridon , Julie Carette , France Leclaire , Roger Leger , Martin Robitaille
发明人: Peter Bakis , Dominique Bridon , Julie Carette , France Leclaire , Roger Leger , Martin Robitaille
CPC分类号: A61K38/2242 , A61K47/62
摘要: This invention relates to long lasting natriuretic peptide (NP) derivatives. The NP derivative has a NP peptide and a reactive entity coupled to the NP peptide. The reactive entity is able to covalently bond with a functionality on a blood component. In particular, this invention relates to NP derivatives having an extended in vivo half-life, and method for the treatment of cardiovascular diseases and disorders such as acute decompensated congestive heart failure (CHF) and chronic CHF.
摘要翻译: 本发明涉及长效利钠肽(NP)衍生物。 NP衍生物具有NP肽和与NP肽偶联的反应性实体。 反应性实体能够与血液成分上的官能团共价键合。 特别地,本发明涉及具有延长的体内半衰期的NP衍生物,以及用于治疗心血管疾病和疾病如急性失代偿性充血性心力衰竭(CHF)和慢性CHF的方法。
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公开(公告)号:US20050103916A1
公开(公告)日:2005-05-19
申请号:US10712883
申请日:2003-11-14
摘要: An apparatus to prevent the tape from falling off the edge of the tape package when unwinding.
摘要翻译: 一种用于防止磁带在展开时从胶带包装边缘脱落的装置。
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公开(公告)号:US20050242225A1
公开(公告)日:2005-11-03
申请号:US11109815
申请日:2005-04-20
申请人: Martin Robitaille , Steve Gagnon
发明人: Martin Robitaille , Steve Gagnon
CPC分类号: B65H59/36 , B65H49/32 , B65H59/04 , B65H2301/41344 , B65H2301/41398 , B65H2301/44921 , B65H2402/10 , B65H2405/4412 , B65H2701/37
摘要: An apparatus to package a plurality of tape spools that can be also used to unwind the tape spools.
摘要翻译: 一种用于包装多个带状卷轴的装置,其也可用于展开卷轴。
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公开(公告)号:US20060071117A1
公开(公告)日:2006-04-06
申请号:US11286339
申请日:2005-11-25
IPC分类号: B65H16/00
CPC分类号: B65H16/06 , B65H16/005 , B65H35/0006
摘要: An apparatus to prevent strip material from falling off the edges of a strip material package when unwinding. The package comprises a generally cylindrical and flangeless core around which the strip material is wound transversely in a plurality of overlapping layers. The apparatus also includes an idler roller. When unwinding, the strip material goes around the idler roller, then around the package, generally in its central portion and then again around the idler roller before being fed to a laminating machine. A method to use the apparatus is also provided.
摘要翻译: 一种防止条带材料在展开时从条带材料包装边缘脱落的装置。 该包装件包括大致圆柱形和无凸缘的芯,围绕该芯材横向地缠绕条带材料在多个重叠层中。 该设备还包括惰轮。 当松开时,条带材料在被送入层压机之前绕过惰轮,然后围绕包装,通常在其中心部分中,然后再绕着惰辊卷绕。 还提供了使用该装置的方法。
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公开(公告)号:US20050279462A1
公开(公告)日:2005-12-22
申请号:US11209818
申请日:2005-08-24
申请人: Martin Robitaille , Steve Cagnon
发明人: Martin Robitaille , Steve Cagnon
CPC分类号: B65H39/16 , B31F1/2886 , B65H2301/43151 , B65H2403/52 , B65H2511/20 , B65H2701/1762 , Y10T156/1016 , Y10T156/1025 , Y10T156/1702 , Y10T156/1712 , Y10T156/1744 , Y10T156/1788 , B65H2220/02 , B65H2220/04 , B65H2220/11 , B65H2220/09
摘要: This invention relates to an improvement in an apparatus for dispensing a ribbon between layers of web material and more particularly, to an automated and remote positioning system of ribbon dispensers which are precisely positioned with respect to the web material by a controlling and monitoring system and are physically easily accessible for maintenance by an operator. The automated and remote positioning system of ribbon dispensers includes locking means interacting with either the apparatus or with a traversing mechanism such as a lead screw to move the ribbon dispensers.
摘要翻译: 本发明涉及一种用于在卷筒纸材料层之间分配带状物的装置的改进,更具体地说,涉及一种色带分配器的自动和远程定位系统,其通过控制和监测系统相对于幅材材料精确定位,并且 物理上方便操作者进行维护。 色带分配器的自动和远程定位系统包括与装置或与诸如导螺杆的横动机构相互作用的锁定装置,以移动色带分配器。
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公开(公告)号:US20120132599A1
公开(公告)日:2012-05-31
申请号:US13389120
申请日:2010-07-22
申请人: Martin Robitaille
发明人: Martin Robitaille
IPC分类号: D06F57/00
CPC分类号: D06F57/12 , D06F57/122
摘要: The present invention discloses an open air dryer having one or more layers of flexible clothes dryers. Each clothes dryer is made of at least one generally rectangular piece of breathable fabric or net like material mounted on two parallel support bars made of a rigid material. The length of each layer is fully adjustable. Each support bar is held by at least one hook and preferably two hooks to any external structures such as walls, dryer, washer or other self-supporting structure.
摘要翻译: 本发明公开了一种具有一层或多层柔性干衣机的露天干燥机。 每个干衣机由安装在由刚性材料制成的两个平行支撑杆上的至少一个通常矩形的透气织物或网状材料制成。 每层的长度是完全可调的。 每个支撑杆由至少一个钩子和优选地两个钩子保持到任何外部结构,例如墙壁,干燥器,垫圈或其他自支撑结构。
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公开(公告)号:US20060241019A1
公开(公告)日:2006-10-26
申请号:US10565900
申请日:2004-07-26
CPC分类号: A61K38/28 , A61K47/643 , C07K14/62
摘要: The present invention relates to an insulin derivative comprising an insulin molecule and a reactive group for covalently bonding a blood component, wherein preferably the insulin molecule is human natural insulin molecule and the reactive group is coupled to an amino acid of the insulin molecule at a position selected from the positions Gly A1, Phe B1 and Lys B29.
摘要翻译: 本发明涉及包含胰岛素分子和用于共价键合血液成分的反应性基团的胰岛素衍生物,其中优选地,胰岛素分子是人天然胰岛素分子,并且反应性基团与胰岛素分子的氨基酸在位置 选自Gly A1,Phe B1和Lys B29。
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公开(公告)号:US07121497B2
公开(公告)日:2006-10-17
申请号:US11286339
申请日:2005-11-25
CPC分类号: B65H16/06 , B65H16/005 , B65H35/0006
摘要: An apparatus to prevent strip material from falling off the edges of a strip material package when unwinding. The package comprises a generally cylindrical and flangeless core around which the strip material is wound transversely in a plurality of overlapping layers. The apparatus also includes an idler roller. When unwinding, the strip material goes around the idler roller, then around the package, generally in its central portion and then again around the idler roller before being fed to a laminating machine. A method to use the apparatus is also provided.
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