公开(公告)号：US08989841B2

公开(公告)日：2015-03-24

申请号：US13018849

申请日：2011-02-01

申请人： George J. Misic

发明人： George J. Misic

IPC分类号： A61B5/055 ,  G01R33/28 ,  G01R33/36 ,  G01R33/34

CPC分类号： G01R33/285 ,  A61B5/055 ,  G01R33/34084 ,  G01R33/3628

摘要： An interface device enables an intracavity probe to be used with a magnetic resonance (MR) system for the purpose of obtaining images or spectra of a region of interest within a cavity of a patient. The probe includes a shaft, a balloon at one end thereof, and a coil loop within the balloon. The coil loop preferably includes two drive capacitors and a tuning capacitor, all of which in series. A junction node between the drive capacitors serves as a ground for electrically balancing the coil loop. Diametrically opposite the junction node, the tuning capacitor enables the coil loop to resonate at the operating frequency of the MR system. Across each drive capacitor is connected an output cable having an electrical length of SL+n(λ/4). The output cables terminate in a plug that is used to connect the coil loop to the interface device.

摘要翻译： 接口装置能够使腔内探针与磁共振（MR）系统一起使用，以获得患者空腔内感兴趣区域的图像或光谱。 探针包括轴，其一端处的气囊和气囊内的线圈环。 线圈环优选地包括两个串联的驱动电容器和调谐电容器。 驱动电容器之间的结节点用作电平衡线圈回路的接地。 调谐电容与连接节点完全相反，使得线圈环能够在MR系统的工作频率下谐振。 在每个驱动电容器之间连接一个电长度为SL + n（λ/ 4）的输出电缆。 输出电缆端接在用于将线圈环连接到接口设备的插头中。

公开(公告)号：US07632245B1

公开(公告)日：2009-12-15

申请号：US10921083

申请日：2004-08-18

申请人： Kevin P. Cowan ,  Frederick W. Trombley, III ,  David M. Reilly ,  David M. Griffiths ,  George J. Misic ,  Keith Callan

发明人： Kevin P. Cowan ,  Frederick W. Trombley, III ,  David M. Reilly ,  David M. Griffiths ,  George J. Misic ,  Keith Callan

IPC分类号： A61M5/19

CPC分类号： A61M5/14526 ,  A61M5/007 ,  A61M2039/0009 ,  A61M2205/3362

摘要： A device for injection of a fluid into a patient includes a container adapted to hold the fluid and defining an outlet through which the fluid can exit the container. A pressurizing mechanism is in connection with the container for pressurizing the fluid, and an actuator is in fluid connection with the outlet. The actuator has a first state in which fluid is prevented from flowing through the outlet and a second state in which fluid can flow through the outlet. The injection device further includes a flow regulator to control the flow rate of fluid in fluid connection with the outlet. The container, the pressurizing mechanism, the actuator and the flow regulator can be MR compatible, thereby making the device suitable for use in or near the bore of an MR scanner.

摘要翻译： 用于向患者注射流体的装置包括适于保持流体并限定出口的容器，流体可通过该出口离开容器。 加压机构与用于对流体加压的容器连接，并且致动器与出口流体连接。 致动器具有防止流体流过出口的第一状态和流体可以流过出口的第二状态。 注射装置还包括流量调节器以控制与出口流体连接的流体的流速。 容器，加压机构，致动器和流量调节器可以是MR兼容的，从而使得该装置适合于在MR扫描器的孔中或附近使用。

公开(公告)号：US20090076378A1

公开(公告)日：2009-03-19

申请号：US11719253

申请日：2005-11-15

申请人： George J. Misic

发明人： George J. Misic

IPC分类号： A61B5/05

CPC分类号： A61B5/055 ,  A61B5/6856 ,  G01R33/34 ,  G01R33/34084 ,  G01R33/34092 ,  G01R33/3415 ,  G01R33/3628 ,  G01R33/3642

摘要： An intracavity probe for use with an MR system allows images or spectra of a region of interest within a cavity of a patient to be obtained. The probe includes a shaft, a balloon at one end thereof, and a coil loop within the balloon. The coil loop preferably includes two drive capacitors and a tuning capacitor, all of which in series. A junction node between the drive capacitors serves as a ground for electrically balancing the coil loop. Diametrically opposite the junction node, the tuning capacitor enables the coil loop to resonate at the operating frequency of the MR system. Across each drive capacitor is connected an output cable having an electrical length of SL+n(λ/4). The output cables terminate in a plug that is used to connect the coil loop to an interface device for the intracavity probe.

摘要翻译： 用于MR系统的腔内探针允许获得患者空腔内的感兴趣区域的图像或光谱。 探针包括轴，其一端处的气囊和气囊内的线圈环。 线圈环优选地包括两个串联的驱动电容器和调谐电容器。 驱动电容器之间的结节点用作电平衡线圈回路的接地。 调谐电容与连接节点完全相反，使得线圈环能够在MR系统的工作频率下谐振。 在每个驱动电容器之间连接有电长度为SL + n（λ/ 4）的输出电缆。 输出电缆端接在用于将线圈环连接到腔内探针的接口装置的插头中。

公开(公告)号：US20080275332A1

公开(公告)日：2008-11-06

申请号：US10597249

申请日：2005-02-22

申请人： Fahad Alradady ,  William J. Monski ,  George J. Misic ,  Robert J. McKenney ,  Timothy S. Zibrat ,  Jaroslaw Wlodarczyk

发明人： Fahad Alradady ,  William J. Monski ,  George J. Misic ,  Robert J. McKenney ,  Timothy S. Zibrat ,  Jaroslaw Wlodarczyk

IPC分类号： A61B5/055 ,  G01R33/3415 ,  G01R3/00

CPC分类号： G01R33/34076 ,  G01R33/5611 ,  Y10T29/4902

摘要： A head coil for use with a parallel-imaging compatible MR system is disclosed, as is a method of making, and a neurovascular array (NVA) equipped with, same. The head coil includes conductive rings and rods configured to produce a plurality of electrically-adjacent primary resonant substructures about a birdcage-like structure, with each such primary resonant substructure including two rods neighboring each other and the short segment of each of the first and second rings interconnecting them. The primary resonant substructures are isolated from each other via a preamplifier decoupling scheme and an offset tuning scheme thereby enabling each primary resonant substructure (i) to receive an MR signal from tissue within its field of view and (ii) to be operatively couplable to one processing channel of the MR system for conveyance of the MR signal received thereby (iii) while being simultaneously decoupled from the other primary resonant substructures.

摘要翻译： 公开了一种与并行成像兼容的MR系统一起使用的头部线圈，以及制造的方法以及配备有它的神经血管阵列（NVA）。 头部线圈包括导电环和杆，其被配置为产生围绕鸟笼状结构的多个电相邻的初级谐振子结构，其中每个这样的初级谐振子结构包括彼此相邻的两个杆和第一和第二 相互连接的环。 主谐振子结构通过前置放大器解耦方案和偏移调谐方案彼此隔离，从而使得每个初级谐振子结构（i）能够从其视场内的组织接收MR信号，并且（ii）可操作地耦合到一个 用于传送由此接收的MR信号的MR系统的处理通道（iii）同时与另一个初级谐振子结构分离。

公开(公告)号：US06512374B1

公开(公告)日：2003-01-28

申请号：US09558493

申请日：2000-04-26

申请人： George J. Misic ,  John Dolinar ,  William J. Monski ,  Theodore Reisker ,  Dennis Manley

发明人： George J. Misic ,  John Dolinar ,  William J. Monski ,  Theodore Reisker ,  Dennis Manley

IPC分类号： G01V300

CPC分类号： G01R33/3657 ,  G01R33/341

摘要： A local or surface coil including a decoupling circuit to allow the coil to operate as a receive-only coil in a host MRI system, in which case the system body coil typically provides the transmit signal. Further, the local or surface coil includes a circuit to defeat the decoupling circuitry for both low power [receive] and high power [transmit] functions to allow the same physical coil to be used as a transmit/receive coil in addition to a receive-only coil. The two modes of the coil allow the user to select the mode of local or surface coil operation best suited to the particular type of imaging being performed.

摘要翻译： 包括去耦电路以允许线圈作为主机MRI系统中的仅接收线圈操作的局部或表面线圈，在这种情况下，系统体线圈通常提供发射信号。 此外，本地或表面线圈包括用于消除低功率[接收]和高功率[发送]功能的去耦电路的电路，以允许相同的物理线圈除了接收 - 只有线圈。 线圈的两种模式允许用户选择最适合于正在执行的特定类型的成像的局部或表面线圈操作的模式。

公开(公告)号：US06223065B1

公开(公告)日：2001-04-24

申请号：US09104656

申请日：1998-06-25

申请人： George J. Misic ,  J. Michael Watral

发明人： George J. Misic ,  J. Michael Watral

IPC分类号： A61B5055

CPC分类号： G01R33/3415

摘要： A method of imaging a subject in an imaging system having a magnetic field and a plurality of receive coils movable with respect to the magnetic field includes sensing the magnetic field by means of at least one sensor having a known position with respect to the subject. At least one of the plurality of receive coils is selected in accordance with the sensing, and is enabled to form an image of the subject. The sensor may include a plurality of sensor coils disposed at differing locations within the magnetic field to sense the differing field amplitudes and/or phases thereof. The differing field intensities cause differing voltage amplitudes and/or phases to be induced on the sensor coils. The differing voltage amplitudes and/or phases are compared to determine the relative positions of the magnetic isocenter of the system and the receive coils to be enabled. Thus, a method for magnetic resonance imaging of a subject in an imaging system having a static magnetic field [B0], a selectively applied gradient magnetic field [B1], a selectively applied transmit excitation radio frequency magnetic field [RF B1], and a plurality of simultaneous data acquisition channels is taught wherein the location of a phased array or other multiple element receive coil and the subject patient with respect to the imaging center of the host magnetic resonance imaging system is determined by sensing the characteristics of one of the magnetic fields.

摘要翻译： 在具有磁场的成像系统和可相对于磁场移动的多个接收线圈的成像系统中对被摄体进行成像的方法包括通过具有相对于被摄体的已知位置的至少一个传感器感测磁场。 根据感测来选择多个接收线圈中的至少一个，并且能够形成被摄体的图像。 传感器可以包括设置在磁场内的不同位置处的多个传感器线圈，以感测不同的场幅度和/或相位。 不同的场强度导致在传感器线圈上感应出不同的电压幅度和/或相位。 比较不同的电压幅度和/或相位以确定系统的磁等角点和要启用的接收线圈的相对位置。 因此，在具有静态磁场[B0]，选择性施加的梯度磁场[B1]，选择性施加的发射激励射频磁场[RF B1]的成像系统中的被摄体的磁共振成像方法 教导了多个同时数据采集通道，其中通过感测磁场中的一个的特性来确定相控阵列或其他多元件接收线圈的位置和对象患者相对于主磁共振成像系统的成像中心的位置 。

公开(公告)号：US20110215807A1

公开(公告)日：2011-09-08

申请号：US13128361

申请日：2009-11-12

申请人： George J. Misic ,  Robert J. McKenny

发明人： George J. Misic ,  Robert J. McKenny

IPC分类号： G01R33/44

CPC分类号： G01R33/341 ,  G01R33/34084 ,  G01R33/3678

摘要： An intracavity probe for use with an MR system allows images and spectra of internal anatomical structures to be obtained. The intracavity probe houses within its balloon-type enclosure a single-element quadrature coil sensitive to both the vertical and horizontal components of the MR signal. The quadrature coil by means of its output line is designed to plug into a dedicated interface device with which to interface the quadrature coil with the MR system. Drive capacitors within the coil in conjunction with the electrical length of the output line and phase shifting networks within the interface device enable complete decoupling of the quadrature coil from the transmit fields generated by the MR system. Preamplifier, power splitting and combining networks within the interface device process voltage signals representative of the horizontal and vertical components of the MR signal and enable them to be conveyed to the input port(s) of the MR system.

摘要翻译： 用于MR系统的腔内探针允许获得内部解剖结构的图像和光谱。 腔内探头在其气球型外壳内容纳有对MR信号的垂直和水平分量敏感的单元正交线圈。 通过其输出线的正交线圈被设计成插入专用接口装置中，以使正交线圈与MR系统接口。 线圈内的驱动电容与输出线的电气长度以及接口装置内的相移网络之间能够使正交线圈与由MR系统产生的发射场完全解耦。 接口设备内的前置放大器，功率分配和组合网络处理代表MR信号的水平和垂直分量的电压信号，并使其能够被传送到MR系统的输入端口。

公开(公告)号：US20110125005A1

公开(公告)日：2011-05-26

申请号：US13018849

申请日：2011-02-01

申请人： George J. Misic

发明人： George J. Misic

IPC分类号： A61B5/055

CPC分类号： G01R33/285 ,  A61B5/055 ,  G01R33/34084 ,  G01R33/3628

摘要： An MR system features an intracavity probe and associated interface device. The probe includes a shaft, a balloon at one end thereof, and a coil loop within the balloon. The loop has two drive capacitors and a tuning capacitor, all of which in series. A junction node between the drive capacitors serves as a ground for electrically balancing the loop. Diametrically opposite the node, the tuning capacitor enables the loop to resonate at the operating frequency of the MR system. The interface allows the MR system to couple the loop to a port of the MR system during a receive cycle thereof and decouple it from the port during a transmit cycle thereof. With its balloon inserted and inflated within a cavity of a patient, the probe allows the MR system to generate images and/or spectra of the region of interest using the MR signals received by the loop.

摘要翻译： MR系统具有腔内探针和相关接口装置。 探针包括轴，其一端处的气囊和气囊内的线圈环。 该回路具有两个串联的驱动电容器和一个调谐电容器。 驱动电容器之间的结节点用作电平衡环路的接地。 与节点完全相反，调谐电容使得环路在MR系统的工作频率下谐振。 该接口允许MR系统在其接收周期期间将环路耦合到MR系统的端口，并在其发射周期期间将其与端口分离。 通过将气球插入并充气到患者的腔内，探针允许MR系统使用循环接收的MR信号来产生感兴趣区域的图像和/或光谱。

公开(公告)号：US07911209B2

公开(公告)日：2011-03-22

申请号：US10597249

申请日：2005-02-22

申请人： Fahad Alradady ,  William J. Monski ,  George J. Misic ,  Robert J. McKenney, Jr. ,  Timothy S. Zibrat ,  Jaroslaw Wlodarczyk

发明人： Fahad Alradady ,  William J. Monski ,  George J. Misic ,  Robert J. McKenney, Jr. ,  Timothy S. Zibrat ,  Jaroslaw Wlodarczyk

IPC分类号： G01V3/00 ,  A61B5/05

CPC分类号： G01R33/34076 ,  G01R33/5611 ,  Y10T29/4902

摘要： A head coil for use with a parallel-imaging compatible MR system is disclosed, as is a method of making, and a neurovascular array (NVA) equipped with, same. The head coil includes conductive rings and rods configured to produce a plurality of electrically-adjacent primary resonant substructures about a birdcage-like structure, with each such primary resonant substructure including two rods neighboring each other and the short segment of each of the first and second rings interconnecting them. The primary resonant substructures are isolated from each other via a preamplifier decoupling scheme and an offset tuning scheme thereby enabling each primary resonant substructure (i) to receive an MR signal from tissue within its field of view and (ii) to be operatively couplable to one processing channel of the MR system for conveyance of the MR signal received thereby (iii) while being simultaneously decoupled from the other primary resonant substructures.

摘要翻译： 公开了一种与并行成像兼容的MR系统一起使用的头部线圈，以及制造的方法以及配备有它的神经血管阵列（NVA）。 头部线圈包括导电环和杆，其被配置为产生围绕鸟笼状结构的多个电相邻的初级谐振子结构，其中每个这样的初级谐振子结构包括彼此相邻的两个杆和第一和第二 相互连接的环。 主谐振子结构通过前置放大器解耦方案和偏移调谐方案彼此隔离，从而使得每个初级谐振子结构（i）能够从其视场内的组织接收MR信号，并且（ii）可操作地耦合到一个 用于传送由此接收的MR信号的MR系统的处理通道（iii）同时与另一个初级谐振子结构分离。

公开(公告)号：US07885704B2

公开(公告)日：2011-02-08

申请号：US11719253

申请日：2005-11-15

申请人： George J. Misic

发明人： George J. Misic

IPC分类号： A61B5/055

CPC分类号： A61B5/055 ,  A61B5/6856 ,  G01R33/34 ,  G01R33/34084 ,  G01R33/34092 ,  G01R33/3415 ,  G01R33/3628 ,  G01R33/3642

摘要： An intracavity probe for use with an MR system allows images or spectra of a region of interest within a cavity of a patient to be obtained. The probe includes a shaft, a balloon at one end thereof, and a coil loop within the balloon. The coil loop preferably includes two drive capacitors and a tuning capacitor, all of which in series. A junction node between the drive capacitors serves as a ground for electrically balancing the coil loop. Diametrically opposite the junction node, the tuning capacitor enables the coil loop to resonate at the operating frequency of the MR system. Across each drive capacitor is connected an output cable having an electrical length of SL+n(λ/4). The output cables terminate in a plug that is used to connect the coil loop to an interface device for the intracavity probe.

摘要翻译： 用于MR系统的腔内探针允许获得患者空腔内的感兴趣区域的图像或光谱。 探针包括轴，其一端处的气囊和气囊内的线圈环。 线圈环优选地包括两个串联的驱动电容器和调谐电容器。 驱动电容器之间的结节点用作电平衡线圈回路的接地。 调谐电容与连接节点完全相反，使得线圈环能够在MR系统的工作频率下谐振。 在每个驱动电容器之间连接一个电长度为SL + n（λ/ 4）的输出电缆。 输出电缆端接在用于将线圈环连接到腔内探针的接口装置的插头中。