-
公开(公告)号:US3933814A
公开(公告)日:1976-01-20
申请号:US397812
申请日:1973-09-17
申请人: Axel Haberkorn , Heinrich Kolling , Eckart Kranz , Jurgen Schramm
发明人: Axel Haberkorn , Heinrich Kolling , Eckart Kranz , Jurgen Schramm
IPC分类号: C07D251/30 , A01N43/64 , A23K1/16 , A61K31/53 , A61K31/535 , A61P33/02 , C07C275/36 , C07C275/60 , C07C275/64 , C07C335/18 , C07D251/26 , C07D251/34 , C07D251/38 , C07D495/04
CPC分类号: C07C275/36 , C07C275/60 , C07C275/64 , C07C335/18
摘要: 1-(4-Phenoxyphenyl)-1,3,5-triazines of the formula: ##SPC1##Or pharmaceutically acceptable nontoxic salts thereof are produced by reacting a urea or thiourea derivative of the formula: ##SPC2##With a carbonylisocyanate of the formula: ##EQU1## to produce a 1-(4-phenoxyphenyl)-1,3,5-triazine as above defined wherein R.sup.11 is hydrogen, and when a 1-(4-phenoxyphenyl)-1,3,5-triazine as above defined wherein R.sup.11 is alkyl is desired, reacting the triazine wherein R.sup.11 is hydrogen with a compound of the formula (alk).sub.n Y.The above defined triazines and their salts are useful as agents against protozoan infections and are particularly useful against coccidiosis.
摘要翻译: 1-(4-苯氧基苯基)-1,3,5-三嗪的下式: