公开(公告)号：US5091563A

公开(公告)日：1992-02-25

申请号：US453154

申请日：1989-12-11

申请人： Yasutaka Tanaka ,  Hidetaka Kojima ,  Yasuo Tsuji

发明人： Yasutaka Tanaka ,  Hidetaka Kojima ,  Yasuo Tsuji

IPC分类号： B01J27/13 ,  B01J27/00 ,  C07B61/00 ,  C07C51/00 ,  C07C51/12 ,  C07C51/48 ,  C07C57/30 ,  C07C67/00

CPC分类号： C07C51/12 ,  Y02P20/584

摘要： A process for preparing an .alpha.-phenylpropionic acid derivative wherein an .alpha.-phenylethyl alcohol derivative is reacted with carbon monoxide in the presence of a catalyst to give an .alpha.-phenylpropionic acid derivative, which comprises carrying out the reaction in either one of the following manners (I), (II) and (III):(I) effecting said reaction in the presence of a rhodium catalyst, as said catalyst, together with an iodine compound in such an amount as to give a Rh to I ratio on an atomic basis of 1:0.5 to 1:6; adjusting the concentration of water in the reaction mixture to a level of 2 mol/l or below; and employing a reaction temperature of 130.degree. C. or below,(II) employing a mixture of a hydrocarbon and an oxygen-containing organic compound as a solvent, or(III) effecting said reaction in the presence of a rhodium catalyst, as said catalyst, and an iodine compound; adding water optionally together with an oxygen-containing organic compound as an extraction solvent to the resulting reaction mixture to thereby separate the same into two layers, i.e., a layer containing the reaction product and an aqueous layer; and repeatedly using the rhodium catalyst contained in said aqueous layer.

公开(公告)号：US5089650A

公开(公告)日：1992-02-18

申请号：US91884

申请日：1987-09-01

申请人： Shigeru Yokota ,  Hiroshi Koyama ,  Hidetaka Kojima

发明人： Shigeru Yokota ,  Hiroshi Koyama ,  Hidetaka Kojima

IPC分类号： B01J31/02 ,  B01J31/18 ,  B01J31/28 ,  C07C68/00

CPC分类号： B01J31/28 ,  B01J31/0268 ,  C07C68/005 ,  B01J2531/16 ,  B01J2531/824 ,  B01J2531/90 ,  B01J31/1805 ,  Y02P20/582

摘要： Disclosed herein is a process for producing a carbonic acid ester by reacting alcohol, carbon monoxide, and oxygen with one another in the presence of a copper compound alone or together with a platinum group metal compound and a reaction accelerator, characterized in that (I) the reaction is carried out in a nitrile compound or amide compound as a solvent, (II) the reaction is carried out in the presence of a reaction accelerator which consists of a quaternary phosphonium halide and a quaternary phosphonium weak acid salt or quaternary phosphonium alkoxide, and/or (III) the reaction is carried out in the presence of a quinoid compound or a compound that changes into a quinoid compound under the reaction conditions.