公开(公告)号：US20210355467A1

公开(公告)日：2021-11-18

申请号：US17388358

申请日：2021-07-29

Applicant: Inscripta, Inc.

Inventor： Aamir Mir ,  Andrew Garst ,  Stephen Federowicz ,  Kyle Seamon

IPC: C12N9/22 ,  C12N15/62 ,  C12N15/11 ,  C12N15/70

Abstract: The present disclosure relates to methods and compositions that allow one to identify in vivo edited cells when employing nucleic-acid guided editing. Additionally provided are automated multi-module instruments for performing editing and selection methods and using the compositions.

公开(公告)号：US20210324355A1

公开(公告)日：2021-10-21

申请号：US17200110

申请日：2021-03-12

Applicant: Inscripta, Inc.

Inventor： Benjamin Mijts ,  Juhan Kim ,  Aamir Mir ,  Andrew Garst ,  Kyle Seamon

IPC: C12N9/22 ,  C12N15/113

Abstract: The present disclosure provides new RNA-guided nucleases for making rational, direct edits to nucleic acids in live cells.

公开(公告)号：US20210301270A1

公开(公告)日：2021-09-30

申请号：US17200089

申请日：2021-03-12

Applicant: Inscripta, Inc.

Inventor： Benjamin Mijts ,  Juhan Kim ,  Aamir Mir ,  Andrew Garst ,  Kyle Seamon

IPC: C12N9/22 ,  C12N15/113

Abstract: The present disclosure provides new RNA-guided nucleases for making rational, direct edits to nucleic acids in live cells.

公开(公告)号：US20210171923A1

公开(公告)日：2021-06-10

申请号：US17084522

申请日：2020-10-29

Applicant: Inscripta, Inc.

Inventor： Benjamin Mijts ,  Juhan Kim ,  Aamir Mir ,  Andrew Garst ,  Kyle Seamon

IPC: C12N9/22 ,  C12N15/113

Abstract: The present disclosure provides new RNA-guided nucleases for making rational, direct edits to nucleic acids in live cells.

公开(公告)号：US10883095B1

公开(公告)日：2021-01-05

申请号：US16837212

申请日：2020-04-01

Applicant: Inscripta, Inc.

Inventor： Benjamin Mijts ,  Juhan Kim ,  Aamir Mir ,  Andrew Garst ,  Kyle Seamon

IPC: C12N9/22 ,  C12N15/113

Abstract: The present disclosure provides new RNA-guided nucleases for making rational, direct edits to nucleic acids in live cells.

公开(公告)号：US10724021B1

公开(公告)日：2020-07-28

申请号：US16868472

申请日：2020-05-06

Applicant: Inscripta, Inc.

Inventor： Juhan Kim ,  Benjamin Mijts ,  Aamir Mir ,  Andrew Garst ,  Kyle Seamon

IPC: C12N9/22 ,  C12N15/10 ,  C12N15/74 ,  C12N15/81 ,  C12N15/85 ,  C12N15/90

Abstract: The present disclosure provides novel RNA-guided enzymes for making rational and direct edits to the genome of live cells.

公开(公告)号：US20200181592A1

公开(公告)日：2020-06-11

申请号：US16798309

申请日：2020-02-22

Applicant: Inscripta, Inc.

Inventor： Benjamin Mijts ,  Juhan Kim ,  Aamir Mir ,  Kyle Seamon ,  Andrew Garst

IPC: C12N9/22

Abstract: The present disclosure provides engineered RNA-guided enzymes for editing live cells.