公开(公告)号：US10273407B2

公开(公告)日：2019-04-30

申请号：US16117453

申请日：2018-08-30

Applicant: INTELLIGENT MATERIAL SOLUTIONS, INC. ,  THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA

Inventor： Joshua E. Collins ,  Howard Y. Bell ,  Xingchen Ye ,  Christopher Bruce Murray

IPC: B42D15/00 ,  C09K11/77 ,  C01F17/00 ,  B82Y30/00 ,  C30B7/08

Abstract: Monodisperse particles having: a single pure crystalline phase of a rare earth-containing lattice, a uniform three-dimensional size, and a uniform polyhedral morphology are disclosed. Due to their uniform size and shape, the monodisperse particles self assemble into superlattices. The particles may be luminescent particles such as down-converting phosphor particles and up-converting phosphors. The monodisperse particles of the invention have a rare earth-containing lattice which in one embodiment may be an yttrium-containing lattice or in another may be a lanthanide-containing lattice. The monodisperse particles may have different optical properties based on their composition, their size, and/or their morphology (or shape). Also disclosed is a combination of at least two types of monodisperse particles, where each type is a plurality of monodisperse particles having a single pure crystalline phase of a rare earth-containing lattice, a uniform three-dimensional size, and a uniform polyhedral morphology; and where the types of monodisperse particles differ from one another by composition, by size, or by morphology. In a preferred embodiment, the types of monodisperse particles have the same composition but different morphologies. Methods of making and methods of using the monodisperse particles are disclosed.

公开(公告)号：US10066163B2

公开(公告)日：2018-09-04

申请号：US15678344

申请日：2017-08-16

Applicant: INTELLIGENT MATERIAL SOLUTIONS, INC. ,  THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA

Inventor： Joshua E. Collins ,  Howard Y. Bell ,  Xingchen Ye ,  Christopher Bruce Murray

IPC: C09K11/77 ,  B82Y30/00 ,  C30B7/08 ,  B42D15/00 ,  C01F17/00

CPC classification number: C09K11/7791 ,  B42D15/00 ,  B82Y30/00 ,  C01F17/0031 ,  C01F17/0043 ,  C01F17/0062 ,  C01F17/0087 ,  C01P2002/52 ,  C01P2002/54 ,  C01P2002/72 ,  C01P2002/84 ,  C01P2004/04 ,  C01P2004/10 ,  C01P2004/11 ,  C01P2004/16 ,  C01P2004/20 ,  C01P2004/32 ,  C01P2004/40 ,  C01P2004/42 ,  C01P2004/52 ,  C01P2004/62 ,  C01P2004/64 ,  C09K11/7773 ,  C30B7/08 ,  Y10T428/2933

Abstract: Monodisperse particles having: a single pure crystalline phase of a rare earth-containing lattice, a uniform three-dimensional size, and a uniform polyhedral morphology are disclosed. Due to their uniform size and shape, the monodisperse particles self assemble into superlattices. The particles may be luminescent particles such as down-converting phosphor particles and up-converting phosphors. The monodisperse particles of the invention have a rare earth-containing lattice which in one embodiment may be an yttrium-containing lattice or in another may be a lanthanide-containing lattice. The monodisperse particles may have different optical properties based on their composition, their size, and/or their morphology (or shape). Also disclosed is a combination of at least two types of monodisperse particles, where each type is a plurality of monodisperse particles having a single pure crystalline phase of a rare earth-containing lattice, a uniform three-dimensional size, and a uniform polyhedral morphology; and where the types of monodisperse particles differ from one another by composition, by size, or by morphology. In a preferred embodiment, the types of monodisperse particles have the same composition but different morphologies. Methods of making and methods of using the monodisperse particles are disclosed.

公开(公告)号：US10054593B2

公开(公告)日：2018-08-21

申请号：US15174633

申请日：2016-06-06

Applicant: INTELLIGENT MATERIAL SOLUTIONS, INC. ,  LEIDEN UNIVERSITY MEDICAL CENTER ,  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES

Inventor： Howard Y. Bell ,  Joshua E. Collins ,  Paul L. A. M. Corstjens ,  Sukwan Handali ,  Hans J. Tanke

IPC: G01N33/58

CPC classification number: G01N33/582 ,  G01N2458/40

Abstract: New methods and assays for multiplexed detection of analytes using phosphors that are uniform in morphology, size, and composition based on their unique optical lifetime signatures are described herein. The described assays and methods can be used for imaging or detection of multiple unique chemical or biological markers simultaneously in a single assay readout.