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361 条记录 (耗时 0.052 秒)

    Plug-flow regeneration process
    25.
    发明授权
    Plug-flow regeneration process 有权
    插管再生过程

    公开(公告)号：US07763666B2

    公开(公告)日：2010-07-27

    申请号：US11572905

    申请日：2005-07-28

    申请人： Gregory Mark Vero ,  Paul Smith

    发明人： Gregory Mark Vero ,  Paul Smith

    IPC分类号： C08J5/20

    CPC分类号： C02F1/42 ,  B01J49/05 ,  B01J49/50 ,  C02F2303/16

    摘要： A process for the regeneration of loaded ion-exchange resin comprising (a) providing loaded resin for regeneration; (b) providing first stage and third stage regenerant suitable for regenerating loaded resin; (c) providing a plurality of regeneration vessels; (d) filling a regeneration vessel with a desired amount of the loaded resin before filling another regeneration vessel; (e) once a regeneration vessel has been filled, contacting the loaded resin within the vessel with first stage regenerant in a plug flow to provide a first stage regenerated resin; (f) contacting the first stage regenerated resin with third stage regenerant in a plug flow to provide regenerated resin and (g) removing and collecting third stage regenerant from a vessel containing regenerated resin and adding the collected regenerant to the first stage regenerant.

    摘要翻译： 一种负载离子交换树脂的再生方法，包括：（a）提供用于再生的负载树脂; （b）提供适于再生负载树脂的第一级和第三级再生剂; （c）提供多个再生容器; （d）在填充另一个再生容器之前，用所需量的负载树脂填充再生容器; （e）一旦已经填充了再生容器，使容器内的负载树脂与活塞流中的第一级再生剂接触以提供第一级再生树脂; （f）使第一级再生树脂与活塞流中的第三级再生剂接触以提供再生树脂，（g）从含有再生树脂的容器中除去和收集第三级再生剂，并将收集的再生剂加入到第一级再生剂中。

    SPATIALLY SELECTIVE FIXED-OPTICS MULTICOLOR FLUORESCENCE DETECTION SYSTEM FOR A MULTICHANNEL MICROFLUIDIC DEVICE, AND METHOD FOR DETECTION
    26.
    发明申请
    SPATIALLY SELECTIVE FIXED-OPTICS MULTICOLOR FLUORESCENCE DETECTION SYSTEM FOR A MULTICHANNEL MICROFLUIDIC DEVICE, AND METHOD FOR DETECTION 有权
    用于多通道微流体装置的空间选择性固定化多功能荧光检测系统及其检测方法

    公开(公告)号：US20100165339A1

    公开(公告)日：2010-07-01

    申请号：US11993852

    申请日：2006-06-26

    申请人： Nicole Y. Morgan ,  Paul Smith ,  Ed Wellner

    发明人： Nicole Y. Morgan ,  Paul Smith ,  Ed Wellner

    IPC分类号： G01J3/28 ,  G01J1/58

    CPC分类号： G01N21/6456 ,  G01N2021/6417 ,  G01N2021/6423 ,  G01N2021/6478 ,  G01N2021/6484

    摘要： A fixed-optics system for detecting fluorescence light emitted from one or more spatially selected volumes (S), e.g., in one or more microfluidic channels, comprises a detection optical fiber (60) corresponding to each selected volume and a ball lens (110) adjacent to one end of each optical fiber, wherein the ball lens has a diameter (D) larger than the diameter of the optical fiber and a distance (d1) between the ball lens and the optical fiber is in a range of 3 to 40 times the diameter of the optical fiber, so that due to a quasi-focusing configuration light emitted from the spatially selected volume and received by the ball lens converges onto the end (60a) of the optical fiber.

    摘要翻译： 用于检测从一个或多个空间选择的体积（S）发射的荧光的固定光学系统，例如在一个或多个微流体通道中，包括对应于每个选定体积的检测光纤（60）和球透镜（110） 邻近各光纤的一端，其中，所述球透镜的直径（D）大于所述光纤的直径，并且所述球透镜与所述光纤之间的距离（d1）在3〜40倍的范围内 光纤的直径，使得由于准聚焦配置，从空间选择的体积发射并由球透镜接收的光会聚到光纤的端部（60a）上。

    Clothing Packing Apparatus
    27.
    发明申请
    Clothing Packing Apparatus 有权
    服装包装设备

    公开(公告)号：US20090277138A1

    公开(公告)日：2009-11-12

    申请号：US12440356

    申请日：2007-09-07

    申请人： Paul Smith ,  Wai Kwon Tang

    发明人： Paul Smith ,  Wai Kwon Tang

    IPC分类号： A41H33/00 ,  B65B5/04

    CPC分类号： D06F89/02 ,  D06F89/005

    摘要： A clothing packing apparatus for folding a clothing article, such as a suit, comprising a spacing material to separate parts of the folded clothing article comprises a parts that partial overlay a fold line in the aligned sleeves and the body of an article of clothing; a slit for folding the sleeves independently; gripping surfaces to engage the clothing article; rounded/tapered edges to eliminate pressure compressions; pre-formed bands to improve folding performance; and a casing for storage and transit. The spacing material is preferably formed of foam capable of forming a continuous U-shaped curve along the fold lines and an anti-collapsible structure when folded with the clothing article.

    摘要翻译： 一种衣服包装装置，用于折叠诸如衣服的衣服制品，其包括用于分离折叠的衣服制品的部分的间隔材料，其包括部分地覆盖对齐的袖子中的折叠线和衣服的身体的部分; 用于独立地折叠套筒的狭缝; 抓握表面以接合衣物; 圆形/锥形边缘消除压力压缩; 预先形成的乐队，以提高折叠表演; 和一个用于存储和运输的套管。 间隔材料优选由能够沿折线形成连续的U形曲线的泡沫形成，并且当与服装物品折叠时具有防折叠结构。

    DOWNHOLE DEPLOYMENT VALVES
    28.
    发明申请
    DOWNHOLE DEPLOYMENT VALVES 有权
    井下部分阀

    公开(公告)号：US20080245531A1

    公开(公告)日：2008-10-09

    申请号：US12098264

    申请日：2008-04-04

    申请人： Joe Noske ,  David Iblings ,  David Pavel ,  David J. Brunnert ,  Paul Smith ,  Michael Brian Grayson

    发明人： Joe Noske ,  David Iblings ,  David Pavel ,  David J. Brunnert ,  Paul Smith ,  Michael Brian Grayson

    IPC分类号： E21B34/06

    CPC分类号： E21B34/14 ,  E21B21/08 ,  E21B21/10 ,  E21B2034/005 ,  Y10T137/7898

    摘要： Methods and apparatus enable reliable and improved isolation between two portions of a bore extending through a casing string disposed in a borehole. A downhole deployment valve (DDV) may provide the isolation utilizing a valve member such as a flapper that is disposed in a housing of the DDV and is designed to close against a seat within the housing. The DDV includes an operating mechanism for opening/closing the DDV. In use, pressure in one portion of a well that is in fluid communication with a well surface may be bled off and open at well surface while maintaining pressure in another portion of the casing string beyond the DDV.

    摘要翻译： 方法和装置能够在延伸穿过设置在钻孔中的套管柱的孔的两个部分之间实现可靠和改进的隔离。 井下展开阀（DDV）可以利用诸如挡板的阀构件来提供隔离，所述阀构件设置在DDV的壳体中并被设计成抵靠壳体内的座。 DDV包括用于打开/关闭DDV的操作机构。 在使用中，与井表面流体连通的井的一部分中的压力可以在井表面被排出并打开，同时保持套管柱的另一部分中的压力超过DDV。

    Potent cytotoxicity and inhibition of pan-cell cycle progression by an alkylating anthraquinone
    30.
    发明申请
    Potent cytotoxicity and inhibition of pan-cell cycle progression by an alkylating anthraquinone 审中-公开
    通过烷基化蒽醌对细胞周期进程的有效细胞毒性和抑制作用

    公开(公告)号：US20070208085A1

    公开(公告)日：2007-09-06

    申请号：US11655043

    申请日：2007-01-17

    申请人： Agamemnon Epenetos ,  Klaus Pors ,  Paul Smith ,  Laurence Patterson

    发明人： Agamemnon Epenetos ,  Klaus Pors ,  Paul Smith ,  Laurence Patterson

    IPC分类号： A61K31/137

    CPC分类号： A61K31/137

    摘要： The present invention generally relates to chemotherapeutic treatment of proliferative disorders, such as cancer. The invention more specifically relates to inhibition of pan-cell cycle progression with alkylating anthraquinones, which may inhibit mitotic commitment, lead to limited expression of G2 arrest and force cells to enter polyploidy via an aberrant mitosis. The methods of the invention are particularly useful in the treatment of chemotherapy-resistant cancers.

    摘要翻译： 本发明一般涉及增生性疾病如癌症的化学治疗。 本发明更具体地涉及用烷基化蒽醌抑制泛细胞周期进程，其可抑制有丝分裂承诺，导致G2阻滞的有限表达，并且通过异常有丝分裂使强制细胞进入多倍体。 本发明的方法在化疗耐药性癌症的治疗中特别有用。