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25 条记录 (耗时 0.035 秒)

    Poly(ester amide) filler blends for modulation of coating properties
    22.
    发明授权
    Poly(ester amide) filler blends for modulation of coating properties 有权
    用于调节涂层性能的聚（酯酰胺）填料混合物

    公开(公告)号：US07390497B2

    公开(公告)日：2008-06-24

    申请号：US10976551

    申请日：2004-10-29

    申请人： Jessica Renee DesNoyer ,  Stephen Dirk Pacetti ,  Syed Faiyaz Shmed Hossainy ,  Lothar Kleiner ,  Yiwen Tang ,  Gina Zhang

    发明人： Jessica Renee DesNoyer ,  Stephen Dirk Pacetti ,  Syed Faiyaz Shmed Hossainy ,  Lothar Kleiner ,  Yiwen Tang ,  Gina Zhang

    IPC分类号： A61K31/00 ,  A61L31/10 ,  A61L27/34 ,  A61L29/08 ,  C08G63/02

    CPC分类号： C09D177/12 ,  A61L31/06 ,  A61L31/10 ,  Y10S623/90 ,  Y10T428/31725 ,  Y10T428/31786 ,  C08L77/12

    摘要： Provided herein is a PEA polymer blend and coatings or implantable devices formed therefrom. The PEA polymer blend is formed of a PEA polymer and a material capable of hydrogen bonding with the PEA. The PEA polymer blend can form a coating on an implantable device, one example of which is a stent. The coating can optionally include a biobeneficial material and/or optionally with a bioactive agent. The implantable device can be used to treat or prevent a disorder such as one of atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, and combinations thereof.

    摘要翻译： 本文提供了由其形成的PEA聚合物共混物和涂层或可植入装置。 PEA聚合物共混物由PEA聚合物和能够与PEA氢键合的材料形成。 PEA聚合物共混物可以在可植入装置上形成涂层，其一个实例是支架。 涂层可任选地包括生物有益材料和/或任选地含有生物活性剂。 可植入装置可用于治疗或预防动脉粥样硬化，血栓形成，再狭窄，出血，血管解剖或穿孔之一，血管动脉瘤，易损斑块，慢性完全闭塞，跛行，静脉和人造移植物的吻合增殖等障碍 导管阻塞，输尿管阻塞，肿瘤阻塞及其组合。

    Therapeutic composition and a method of coating implantable medical devices
    24.
    发明申请
    Therapeutic composition and a method of coating implantable medical devices 有权
    治疗组合物和可植入医疗器械的涂敷方法

    公开(公告)号：US20070065479A1

    公开(公告)日：2007-03-22

    申请号：US11602678

    申请日：2006-11-20

    申请人： Gina Zhang ,  Syed Hossainy ,  Eugene Park ,  Qi Wang

    发明人： Gina Zhang ,  Syed Hossainy ,  Eugene Park ,  Qi Wang

    IPC分类号： A61F2/02

    CPC分类号： A61L31/16 ,  A61L31/14 ,  A61L2300/416 ,  A61L2300/802

    摘要： A method of making a therapeutic composition, as well as the therapeutic composition so made, is disclosed. The method comprises mixing a hydrophobic drug with an aqueous buffer solution and adding a surfactant to the aqueous buffer solution to form the therapeutic composition. A implantable medical device with the therapeutic composition and a method of making a coating for an implantable medical device containing the therapeutic composition is also disclosed.

    摘要翻译： 公开了制备治疗组合物的方法以及如此制备的治疗组合物。 该方法包括将疏水性药物与缓冲水溶液混合，并将表面活性剂加入到缓冲液水溶液中以形成治疗组合物。 还公开了具有治疗组合物的可植入医疗装置和制备用于含有治疗组合物的可植入医疗装置的涂层的方法。