公开(公告)号：US10221160B2

公开(公告)日：2019-03-05

申请号：US14373314

申请日：2013-01-18

申请人： Mycovia Pharmaceuticals, Inc.

发明人： William J. Hoekstra ,  Robert J. Schotzinger ,  Stephen W. Rafferty

IPC分类号： A01N43/40 ,  A61K45/06 ,  C07D401/06 ,  C07F9/6524 ,  C12N9/00 ,  C12N9/02

摘要： The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.

公开(公告)号：US20190010140A1

公开(公告)日：2019-01-10

申请号：US16030228

申请日：2018-07-09

申请人： Mycovia Pharmaceuticals, Inc. ,  The United State of America, as represented by the Secretary, Department of Health and Human Service

发明人： William J. Hoekstra ,  Christopher M. Yates ,  Mark Behnke ,  Asaf Alimardanov ,  Scott A. David ,  Douglas Franklin Fry

IPC分类号： C07D401/06 ,  C07D213/50 ,  C07D405/06 ,  C07D213/30 ,  C07D213/56 ,  C07D213/38

CPC分类号： C07D401/06 ,  C07D213/30 ,  C07D213/38 ,  C07D213/50 ,  C07D213/56 ,  C07D405/06

摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.

公开(公告)号：US10428025B2

公开(公告)日：2019-10-01

申请号：US16280534

申请日：2019-02-20

申请人： Mycovia Pharmaceuticals, Inc. ,  The U.S.A. as represented by the Secretary, Department of Health and Human Services

发明人： William J. Hoekstra ,  Christopher M. Yates ,  Mark Behnke ,  Asaf Alimardanov ,  Scott A. David ,  Douglas Franklin Fry

IPC分类号： C07D213/30 ,  C07D213/50 ,  C07D405/06 ,  C07D213/38 ,  C07D401/06

摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.

公开(公告)号：US10392365B2

公开(公告)日：2019-08-27

申请号：US16241036

申请日：2019-01-07

申请人： Mycovia Pharmaceuticals, Inc. ,  The United States of America, as represented by the Secretary, Department of Health and Human Services

发明人： William J. Hoekstra ,  Christopher M. Yates ,  Mark Behnke ,  Asaf Alimardanov ,  Scott A. David ,  Douglas Franklin Fry

IPC分类号： C07D213/26 ,  C07D401/06 ,  C07D405/06 ,  C07D213/38

摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.

公开(公告)号：US20190169159A1

公开(公告)日：2019-06-06

申请号：US16259096

申请日：2019-01-28

申请人： Mycovia Pharmaceuticals, Inc.

发明人： William J. Hoekstra ,  Robert J. Schotzinger ,  Stephen W. Rafferty

IPC分类号： C07D401/06 ,  A61K45/06 ,  C07F9/6524

摘要： The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.

公开(公告)号：US10077250B2

公开(公告)日：2018-09-18

申请号：US15126359

申请日：2015-03-19

申请人： Mycovia Pharmaceuticals, Inc. ,  The United States of America, as represented by the Secretary Department of Health and Human Services

发明人： William J. Hoekstra ,  Christopher M. Yates ,  Mark Behnke ,  Asaf Alimardanov ,  Scott A. David ,  Douglas Franklin Fry

IPC分类号： C07D401/06 ,  C07D213/56

CPC分类号： C07D401/06 ,  C07D213/38 ,  C07D213/50 ,  C07D213/56 ,  C07D405/06

摘要： The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.