公开(公告)号：US20180010111A1

公开(公告)日：2018-01-11

申请号：US15708669

申请日：2017-09-19

Applicant: NOVOZYMES A/S

Inventor： Allan Svendsen ,  Annette Helle Johansen ,  Mads Bjoernvad ,  Frank W. Rasmussen ,  Michael Skjoet ,  Signe Eskildsen Larsen ,  Jens Oebro ,  Svend Kaasgaard ,  Lars Beier

IPC: C12N9/28

CPC classification number: C12N9/2417

Abstract: The present invention relates to variants of an alpha-amylase having improved stability to chelating agents relative to its parent enzyme, compositions comprising the variants, nucleic acids encoding the variants, methods of producing the variants, and methods for using the variants.

公开(公告)号：US20160326506A1

公开(公告)日：2016-11-10

申请号：US15218599

申请日：2016-07-25

Applicant: NOVOZYMES A/S

Inventor： Svend Kaasgaard ,  Jens Oebro ,  Signe Eskildsen Larsen ,  Allan Svendsen ,  Annette Helle Johansen ,  Michael Skjoet ,  Carsten Andersen ,  Lars Beier ,  Esben Peter Friis ,  Miguel Duarte Guilherme Pereira Toscano ,  Mads Bjoernvad ,  Frank Winther Rasmussen ,  Liv Spaanger Christiansen

IPC: C12N9/28

CPC classification number: C12N9/2417 ,  C12Y302/01001

Abstract: The present invention relates to variants of a parent alpha-amylase. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

Abstract translation: 本发明涉及母体α-淀粉酶的变体。 本发明还涉及编码这些变体的多核苷酸; 核酸构建体，载体和包含多核苷酸的宿主细胞; 以及使用这些变体的方法。

公开(公告)号：US11453868B2

公开(公告)日：2022-09-27

申请号：US17204244

申请日：2021-03-17

Applicant: NOVOZYMES A/S

Inventor： Allan Svendsen ,  Annette Helle Johansen ,  Mads Bjoernvad ,  Frank W. Rasmussen ,  Michael Skjoet ,  Signe Eskildsen Larsen ,  Jens Oebro ,  Svend Kaasgaard ,  Lars Beier

IPC: C12N9/28

Abstract: The present invention relates to variants of an alpha-amylase having improved stability to chelating agents relative to its parent enzyme, compositions comprising the variants, nucleic acids encoding the variants, methods of producing the variants, and methods for using the variants.

公开(公告)号：US10167458B2

公开(公告)日：2019-01-01

申请号：US15218599

申请日：2016-07-25

Applicant: NOVOZYMES A/S

Inventor： Svend Kaasgaard ,  Jens Oebro ,  Signe Eskildsen Larsen ,  Allan Svendsen ,  Annette Helle Johansen ,  Michael Skjoet ,  Carsten Andersen ,  Lars Beier ,  Esben Peter Friis ,  Miguel Duarte Guilherme Pereira Toscano ,  Mads Bjoernvad ,  Frank Winther Rasmussen ,  Liv Spaanger Christiansen

IPC: C12N9/28

Abstract: The present invention relates to variants of a parent alpha-amylase. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

公开(公告)号：US09382524B2

公开(公告)日：2016-07-05

申请号：US14193478

申请日：2014-02-28

Applicant: Novozymes A/S

Inventor： Werner Besenmatter ,  Esben Peter Friis ,  Keith Gibson ,  Frank Winther Rasmussen ,  Michael Skjoet

IPC: C12N9/42 ,  C12N9/26 ,  C11D3/386

CPC classification number: C12N9/2437 ,  C11D3/38636 ,  C12N9/2408 ,  C12N9/2434 ,  C12Y302/01151

Abstract: The present invention relates to variants of a parent xyloglucanase. The present invention also relates to polynucleotides encoding the variant xyloglucanases and to nucleic acid constructs, vectors, and host cells comprising the polynucleotide.

Abstract translation: 本发明涉及亲本木葡聚糖酶的变体。 本发明还涉及编码变体木葡聚糖酶的多核苷酸以及包含多核苷酸的核酸构建体，载体和宿主细胞。

公开(公告)号：US20150023945A1

公开(公告)日：2015-01-22

申请号：US14500419

申请日：2014-09-29

Applicant: Novozymes A/S

Inventor： Mikkel Klausen ,  Marie Allesen Holm ,  Leonardo De Maria ,  Michael Skjoet

IPC: C12N9/36 ,  C11D3/386 ,  A23K1/165 ,  A61K38/47

CPC classification number: C12N9/2462 ,  A23K20/189 ,  A61K38/47 ,  C11D3/38636 ,  C12Y302/01017

Abstract: The present invention is directed to lysozyme variants and nucleotide sequences encoding same. The lysozyme variants have antimicrobial and/or lysozyme activity and comprise an alteration of an amino acid sequence at one or more positions. The present invention is also directed to methods for producing and of using the Opisthocomus hoazin lysozyme and the lysozyme variants of the present invention as antimicrobial agents.

Abstract translation: 本发明涉及溶菌酶变体和编码其的核苷酸序列。 溶菌酶变体具有抗微生物和/或溶菌酶活性，并且包括在一个或多个位置上氨基酸序列的改变。 本发明还涉及用于制造和使用本发明的眼药水溶菌酶和溶菌酶变体作为抗微生物剂的方法。