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公开(公告)号：US20240360426A1
公开(公告)日：2024-10-31
申请号：US18675391
申请日：2024-05-28
申请人： Novozymes A/S
发明人： Hengxiao Zhai , Jesper Vind , Lars Kobberoe Skov , Qian Zhang , Ester Santigosa , Jose-Otavio B. Sorbara , Aurelia Anne Catherine Charlotte Seon , Carrie Louise Walk
IPC分类号： C12N9/16 , A23K10/14 , A23K20/174 , A23K20/189 , A23K20/20 , C12N15/75
CPC分类号： C12N9/16 , A23K10/14 , A23K20/174 , A23K20/189 , A23K20/30 , C12N15/75 , C12Y301/03008
摘要： Methods of producing phytase variants useful for liberating phosphorous from phytate substrates, for reducing phytate levels in animal manure, for treating vegetable proteins, for improving the nutritional value of animal feed, for improving nutrient retention and/or digestibility in an animal, and for increasing weight gain, improving specific growth rate and/or improving Feed Conversion Ratio of an animal.
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2.发明公开公开(公告)号：US20240325507A1
公开(公告)日：2024-10-03
申请号：US18590736
申请日：2024-02-28
IPC分类号： A61K38/47 , A23K20/189 , A23K50/30 , A61P31/00
CPC分类号： A61K38/47 , A23K20/189 , A23K50/30 , A61P31/00 , C12Y302/01051
摘要： Disclosed are methods and compositions using glycoside hydrolases, such as an alpha-L-fucosidases, to prevent and/or treat a pathogenic infection and/or diarrhea in an animal wherein the pathogenic infection is caused by a pathogen capable of binding to an animal intestinal cell wherein said binding of the pathogen is dependent on the presence of a pathogen binding site having at least one glycan structure substituted with at least one alpha-1,2-L-fucose moiety comprising administering to the animal an effective amount of a glycoside hydrolase capable of removing the at least one alpha-1,2-L-fucose moiety from the pathogen binding site.
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公开(公告)号：US12102103B2
公开(公告)日：2024-10-01
申请号：US16960332
申请日：2019-01-11
申请人： Novozymes A/S , DSM IP Assets B.V.
IPC分类号： A23K20/189 , A23K10/14 , A23K20/22 , A23K20/24
CPC分类号： A23K20/189 , A23K10/14 , A23K20/22 , A23K20/24 , C12Y302/01008
摘要： The presence of either a calcium source or a carbonate source with GH30 xylanses significantly improves the release of xylan oligomers from maize and other feeds compared to the same xylanases without the calcium or carbonate source. Animal feed and animal feed additives comprising a combination of one or more polypeptides having xylanase activity; and one or more sources of calcium; and/or one or more sources of carbonate, wherein the polypeptide is a GH30 xylanase provide for improved xylan release from feedstuff.
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公开(公告)号：US12037613B2
公开(公告)日：2024-07-16
申请号：US17402099
申请日：2021-08-13
申请人： Novozymes A/S
发明人： Hengxiao Zhai , Jesper Vind , Lars Kobberoe Skov , Qian Zhang , Ester Santigosa , Jose-Otavio B. Sorbara , Aurelia Anne Catherine Charlotte Seon , Carrie Louise Walk
IPC分类号： C12N9/16 , A23K10/14 , A23K20/174 , A23K20/189 , A23K20/20 , C12N15/75
CPC分类号： C12N9/16 , A23K10/14 , A23K20/174 , A23K20/189 , A23K20/30 , C12N15/75 , C12Y301/03008
摘要： The present invention relates to phytase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
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公开(公告)号：US12031164B2
公开(公告)日：2024-07-09
申请号：US16648810
申请日：2018-09-20
申请人： Spogen Biotech Inc.
发明人： Brian M. Thompson , Jorg Augustin , Ashley Siegel
IPC分类号： C12N9/78 , A01N63/22 , A23K10/18 , A23K20/189 , A61K9/00 , A61K35/742 , A61K38/00 , C07K14/32 , C12N9/24 , C12N9/42
CPC分类号： C12N9/78 , A01N63/22 , A23K10/18 , A23K20/189 , A61K9/0056 , A61K35/742 , C07K14/32 , C12N9/2402 , C12N9/2434 , C12Y302/01151 , C12Y305/99007 , A61K38/00 , C07K2319/035
摘要： Fusion proteins containing a targeting sequence, exosporium protein, or exosporium protein fragment that targets the fusion protein to the exosporium of a recombinant Bacillus cereus family member are provided. The fusion proteins further comprise an enzyme having ACC deaminase activity, a phospholipase, a lipase, a xylanase, a xylosidase, a lactonase, a chitosanase, a protease, a glucanase, a phytase, an acid phosphatase, a pectinase, a mannanase, and/or an expansin protein. Also provided are recombinant Bacillus cereus family members that express the fusion proteins, exosporium fragments derived from the recombinant Bacillus cereus family members, and formulations containing the recombinant Bacillus cereus family members or exosporium fragments. Plant seeds treated with the recombinant Bacillus cereus family members, exosporium fragments, or formulations are also provided. The invention further relates to methods for stimulating plant growth and/or promoting plant health using the recombinant Bacillus cereus family members, exosporium fragments, or formulations.
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公开(公告)号：US20240156921A1
公开(公告)日：2024-05-16
申请号：US18550313
申请日：2022-03-14
申请人： DSM IP Assets B.V. , Novozymes A/S
IPC分类号： A61K38/47 , A23K20/189
CPC分类号： A61K38/47 , A23K20/189 , C12Y302/01017
摘要： The present invention relates to a method for improving health status and/or performance of female animals during gestation and/or lactation and young animals thereof comprising administering to the female animals one or more microbial muramidases. The present invention also provides a feed composition for the above method and use thereof.
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公开(公告)号：US11974976B2
公开(公告)日：2024-05-07
申请号：US17355749
申请日：2021-06-23
IPC分类号： A61K31/205 , A23K20/105 , A23K20/147 , A23K20/158 , A23K20/163 , A23K20/189 , A23K50/75 , A61K38/46 , A61K45/06
CPC分类号： A61K31/205 , A23K20/105 , A23K20/147 , A23K20/158 , A23K20/163 , A23K20/189 , A23K50/75 , A61K38/465 , A61K45/06 , C12Y301/00
摘要： The invention relates to animal feeds and feed premixes containing synergistically effective amounts of betaine hydrochloride and a phytase.
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公开(公告)号：US20230405091A1
公开(公告)日：2023-12-21
申请号：US18248616
申请日：2021-10-15
申请人： DSM IP ASSETS B.V. , NOVOZYMES A/S
发明人： Joshua CLAYPOOL , Ghislain SCHYNS
IPC分类号： A61K38/44 , A23K20/189 , A23K20/147 , A23K50/30 , A23K50/75
CPC分类号： A61K38/446 , C12Y115/01001 , A23K20/189 , A23K20/147 , A23K50/30 , A23K50/75
摘要： The present disclosure relates to methods of feeding animals by providing feed additives that modulate the gut microbiome to improve the health, nutrition, and growth performance. The present disclosure further relates to methods of modulating metabolites present in the gastrointestinal tract of an animal. Such modulation includes, for example, modulating the level said metabolites.
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公开(公告)号：US20230346854A1
公开(公告)日：2023-11-02
申请号：US18022401
申请日：2021-08-18
发明人： Michael R. KING , Sona SON , Kyle LEISTIKOW
IPC分类号： A61K35/742 , A61K31/496 , A23K10/18 , A23K50/30 , A23K20/189 , A23K20/195
CPC分类号： A61K35/742 , A61K31/496 , A23K10/18 , A23K50/30 , A23K20/189 , A23K20/195
摘要： The invention relates to direct-fed microbials for use in E. coli inhibition in animals in combination with enrofloxacin. More particularly, the invention relates to isolated Bacillus strains 9, 57, 71, and 126, and strains having all of the identifying characteristics of these strains, for a use comprising the above-mentioned use.
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公开(公告)号：US11751584B2
公开(公告)日：2023-09-12
申请号：US17340271
申请日：2021-06-07
申请人： Novozymes A/S
发明人： Lone Carstensen , Nikolaj Spodsberg , Morten Gjermansen , Jesper Salomon , Kristian Bertel Roemer M. Krogh , Eduardo Antonio Della Pia
IPC分类号： A61K38/00 , A23K20/189 , A23K20/174 , A23K20/22 , A23K20/24 , A23K20/20 , A23K40/10 , A23K10/30 , C12N9/40
CPC分类号： A23K20/189 , A23K10/30 , A23K20/174 , A23K20/22 , A23K20/24 , A23K20/30 , A23K40/10 , C12N9/2465 , C12Y302/01022
摘要： The present invention relates to methods of releasing galactose from legumes using polypeptides having alpha-galactosidase activity. The invention also relates to polypeptides having alpha-galactosidase activity, polynucleotides encoding the polypeptides, nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing the polypeptides. The invention also relates to compositions comprising the polypeptides of the invention and the use of the polypeptides in animal feed.
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