公开(公告)号：US20080214845A1

公开(公告)日：2008-09-04

申请号：US12040615

申请日：2008-02-29

申请人： Michael T. Migawa ,  Xiaojing Wang ,  Eric Swayze ,  Richard H. Griffey

发明人： Michael T. Migawa ,  Xiaojing Wang ,  Eric Swayze ,  Richard H. Griffey

IPC分类号： C07D315/00

CPC分类号： C07H15/232

摘要： The present invention is directed to analogs of aminoglycoside compounds as well as their preparation and use as prophylactic or therapeutics against microbial infection.

摘要翻译： 本发明涉及氨基糖苷类化合物的类似物以及它们作为抗微生物感染的预防或治疗剂的制备和用途。

公开(公告)号：US07943749B2

公开(公告)日：2011-05-17

申请号：US11740998

申请日：2007-04-27

申请人： Stephen Hanessian ,  Janek Szychowski ,  Susanta Sekhar Adhikari ,  Kandasamy Pachamuthu ,  Michael T. Migawa ,  Richard H. Griffey ,  Eric Swayze

发明人： Stephen Hanessian ,  Janek Szychowski ,  Susanta Sekhar Adhikari ,  Kandasamy Pachamuthu ,  Michael T. Migawa ,  Richard H. Griffey ,  Eric Swayze

IPC分类号： C07H15/20 ,  C07H15/22 ,  A01N43/04 ,  A61K31/70

CPC分类号： C07H15/232

摘要： The present invention is directed to analogs of paromomycin having a variety of chemical functional groups attached at the 2″-O-position as well as their preparation and use as prophylactic or therapeutics against microbial infection.

摘要翻译： 本发明涉及具有连接在2“-O-位上的各种化学官能团的巴龙霉素类似物及其制备和用作抗微生物感染的预防或治疗剂。