公开(公告)号：US20060293579A1

公开(公告)日：2006-12-28

申请号：US10553770

申请日：2004-04-21

申请人： Holger Schmitt ,  Michael Grass ,  Volker Rasche

发明人： Holger Schmitt ,  Michael Grass ,  Volker Rasche

IPC分类号： A61B5/05 ,  A61B6/00

CPC分类号： A61B6/481 ,  A61B6/4441 ,  A61B6/504

摘要： The invention relates to an X-ray imaging device for visualizing the blood flow in a coronary vascular tree of a patient. According to the invention a first set (1) of X-ray projection images of the vascular tree is recorded during various phases of the heart cycle with simultaneous recording of the ECG (2) of the patient. By means of a suitable program control, computer means (17) of the device according to the invention a reconstruction then follows of the three-dimensional structure of the vascular tree during the various phases of the heart cycle. The invention proposes, to determine the time-dependent concentration of contrast agent within the reconstructed three-dimensional structure of the vascular tree, that local image areas within the X-ray projection images of the second set (6) assigned to individual vascular segments (5, 8) are located in accordance with the spatial positions of the vascular segments (5, 8) in the relevant phase of the heart cycle. The concentration of contrast agent in the area of the vascular segments (5, 8) is then determined by evaluation of the X-ray absorption within the local image areas found.

摘要翻译： 本发明涉及用于使患者的冠状动脉血管树中的血流可视化的X射线成像装置。 根据本发明，在心脏周期的各个阶段记录血管树的X射线投影图像的第一组（1），同时记录患者的ECG（2）。 通过合适的程序控制，根据本发明的装置的计算机装置（17）在心脏周期的各个阶段期间重建血管树的三维结构。 本发明提出，为了确定造影剂在血管树的重建三维结构内的时间依赖性浓度，将第二组（6）的X射线投影图像内的局部图像区域分配给各个血管节段 5,8）根据心脏周期的相关阶段中血管段（5,8）的空间位置来定位。 然后通过评估所发现的局部图像区域内的X射线吸收来确定血管片段（5,8）区域中造影剂的浓度。

公开(公告)号：US20060215815A1

公开(公告)日：2006-09-28

申请号：US10567692

申请日：2004-08-03

申请人： Volker Rasche

发明人： Volker Rasche

IPC分类号： H05G1/10

CPC分类号： A61B6/541 ,  A61B5/0402 ,  A61B6/4441 ,  A61B6/481 ,  A61B6/503 ,  A61B6/504

摘要： The invention relates to a device and a method for producing an image of the heart (5), in which the image is preferably three-dimensional and is reconstructed from a series of X-ray projection pictures from various projection directions. In this connection, the electrocardiogram (7) is recorded in parallel with the X-ray pictures and used by a data processing device (10) to control the picture-taking rate, the X-ray pulse duration, the tube current and/or the tube voltage of the X-ray device (1) in such a way that, during the phase to be displayed of maximum movement of the heart, the mean X-ray exposure rate is higher than during the other phases. The data processing device (10) may furthermore use the electrocardiogram to drive an injection pump (8) for the contrast agent in such a way that an approximately constant contrast display of the vessels is produced with minimum contrast-agent injection despite a variable flowrate in the vascular system.

摘要翻译： 本发明涉及一种用于制作心脏（5）的图像的装置和方法，其中图像优选地是三维的，并且是从各种投影方向的一系列X射线投影图像重建的。 在这方面，心电图（7）与X射线图像并行记录，并由数据处理装置（10）使用，以控制拍摄速度，X射线脉冲持续时间，管电流和/或 X射线装置（1）的管电压使得在要显示心脏的最大运动的相位期间，平均X射线曝光率高于其他阶段期间的平均X射线曝光率。 数据处理装置（10）还可以使用心电图来驱动造影剂的注射泵（8），使得以最小的造影剂注射产生容器的近似恒定的对比度显示，尽管可变流量在 血管系统。

公开(公告)号：US20060159326A1

公开(公告)日：2006-07-20

申请号：US10545184

申请日：2004-01-23

申请人： Volker Rasche ,  Babak Movassaghi

发明人： Volker Rasche ,  Babak Movassaghi

IPC分类号： G06K9/00

CPC分类号： G06T11/008 ,  G06T17/10 ,  G06T2211/404 ,  G06T2211/412

摘要： The invention relates to a method for the 3D modeling of a three-dimensional tubular structure of an examination object from a number of 2D projection images (D) of the tubular structure (H) taken from different projection directions. In order to be able to implement such a method with considerably less user interaction while retaining the same degree of accuracy, the following steps are proposed according to the invention: a) reconstruction of a 3D image (B) from the 2D projection images (D), b) selection of at least one 3D central line point (MO) in the 3D image (B), said 3D central line point being located in the tubular structure (H), c) segmentation of other 3D central line points (M) of the tubular structure (H) in the 3D image (B), d) forward projection of the 3D central line points (M), which have been segmented in the 3D image (B), into the 2D projection images (D′), e) determination of border points of the tubular structure (H) in the 2D projection images (D′) on the basis of the 3D central line points (Z) that have been projected in, and f) back-projection of the border points from the 2D projection images (D′) into the 3D image (B).

摘要翻译： 本发明涉及一种从不同投影方向取得的管状结构（H）的多个2D投影图像（D）的三维管状结构的三维建模方法。 为了能够在保持相同程度的精度的同时实现这种具有相当少的用户交互的方法，根据本发明提出了以下步骤：a）从2D投影图像（D）重建3D图像（B） ），b）选择3D图像（B）中的至少一个3D中心线点（MO），所述3D中心线点位于管状结构（H）中，c）分割其他3D中心线点（M ）D）3D图像（B）中的管状结构（H）的向前投影，d）已经被分割在3D图像（B）中的3D中心线点（M）向前投影到2D投影图像 ），e）基于已经投影的3D中心线点（Z），在2D投影图像（D'）中确定管状结构（H）的边界点，以及f）反投影 从2D投影图像（D'）到3D图像（B）的边界点。

公开(公告)号：US06865248B1

公开(公告)日：2005-03-08

申请号：US09668938

申请日：2000-09-25

申请人： Volker Rasche ,  Michael Grass

发明人： Volker Rasche ,  Michael Grass

IPC分类号： A61B6/00 ,  A61B6/02 ,  G01N23/00

CPC分类号： A61B6/541

摘要： The invention relates to a method of and a device for the formation of a three-dimensional image data set of a periodically moving body organ (11) of a patient (5) by means of an X-ray device (1) which includes an X-ray source and an X-ray detector (3), a motion signal (H, B) which is related to the periodic motion of the body organ (11) being measured simultaneously with the acquisition of the projection data sets (D0, D1, . . . , D16). In order to improve such a method or such a device, notably in order to improve the construction and to reduce the time required for data processing while keeping the radiation dose for the patient as small as possible and while ensuring an as high as possible image quality, the invention proposes to acquire the projection data sets (D0, D1, . . . , D16) necessary for the formation of the three-dimensional image data set successively from different X-ray positions (p0, p1, . . . , p16) which are situated in one plane, to control the X-ray device by means of the motion signal (H, B) in such a manner that a projection data set (D0, D1, . . . , D16) is acquired during a low-motion phase of the body organ (11) in each X-ray position (p0, p1, p16) required for the formation of the three-dimensional image data set, and to use the projection data sets (D0, D1, . . . , D16) acquired during the low-motion phase for the formation of the three-dimensional image data set.

摘要翻译： 本发明涉及一种用于通过X射线装置（1）形成患者（5）的周期性运动的身体器官（11）的三维图像数据集的方法和装置，所述X射线装置包括： X射线源和X射线检测器（3），与获取投影数据组（D0，...）同时测量与身体器官（11）的周期运动相关的运动信号（H，B） D1，...，D16）。 为了改进这种方法或这种装置，特别是为了改善结构并减少数据处理所需的时间，同时保持患者的辐射剂量尽可能小并且同时确保尽可能高的图像质量 本发明提出从不同的X射线位置（p0，p1，...，p16）连续地获取形成三维图像数据所需的投影数据集（D0，D1，... D16） ），以通过运动信号（H，B）以这样的方式控制X射线装置，使得在一个平面内获取投影数据组（D0，D1，...，D16） 在形成三维图像数据集所需的每个X射线位置（p0，p1，p16）中的身体器官（11）的低运动相位，并使用投影数据组（D0，D1，...）。 ...，D16）在形成三维图像数据集的低运动阶段期间获得。

公开(公告)号：US5969525A

公开(公告)日：1999-10-19

申请号：US878363

申请日：1997-06-18

申请人： Johannes C. A. Van Driel ,  Johannes J. Van Vaals ,  Dietrich J. K. Holz ,  Volker Rasche

发明人： Johannes C. A. Van Driel ,  Johannes J. Van Vaals ,  Dietrich J. K. Holz ,  Volker Rasche

IPC分类号： G01R33/385 ,  A61B5/055 ,  G01R33/34 ,  G01R33/3415 ,  G01R33/38 ,  G01R33/3875 ,  G01V3/00

CPC分类号： G01R33/3806

摘要： MR imaging apparatus includes a magnet (1) for generating in an examination zone (3) a uniform, steady magnetic field having substantially parallel lines of force extending in a first direction (Z), a gradient coil system (5) for generating a magnetic gradient field, and an RF coil system for generating RF pulses and for receiving MR signals. The apparatus also includes devices (25,27,31) for generating data from the MR signals, and a reconstruction unit (39) for reconstructing an MR image of the examination zone (3) from a set of the data. A patient support system includes a table top (7) drive means (11) configured for displacement of the table top in the first direction (Z), and a connection (43) for coupling the drive means and the control unit (29). The magnet (1) has a generally toroidal-shaped housing (15) surrounding a bore (17) and has a longitudinal axis (19) extending substantially parallel to the first direction (Z). The housing (15) has a radial thickness (r) in a direction transverse to said axis (19) and a longitudinal thickness (1) in a direction substantially parallel to said axis, the radial thickness being greater than the longitudinal thickness.

摘要翻译： MR成像装置包括：磁体（1），用于在检查区（3）中产生具有在第一方向（Z）上延伸的基本上平行的力线的均匀的稳定磁场;梯度线圈系统（5），用于产生磁 梯度场和用于产生RF脉冲并用于接收MR信号的RF线圈系统。 该装置还包括用于从MR信号产生数据的装置（25,27,31）和用于从一组数据重建检查区（3）的MR图像的重建单元（39）。 患者支撑系统包括被配置为在第一方向（Z）上移动台面的台面（7）驱动装置（11）和用于联接驱动装置和控制单元（29）的连接件（43）。 磁体（1）具有围绕孔（17）的大致环形的壳体（15），并且具有基本上平行于第一方向（Z）延伸的纵向轴线（19）。 壳体（15）在垂直于所述轴线（19）的方向上具有径向厚度（r）和在基本上平行于所述轴线的方向上的纵向厚度（1），径向厚度大于纵向厚度。

公开(公告)号：US07646900B2

公开(公告)日：2010-01-12

申请号：US10567221

申请日：2004-08-09

申请人： Babak Movassaghi ,  Volker Rasche

发明人： Babak Movassaghi ,  Volker Rasche

IPC分类号： G06K9/00

CPC分类号： G06K9/20 ,  G06K2009/00932 ,  G06K2209/05 ,  G06T7/55 ,  G06T2207/30101

摘要： The invention relates to a method for the reconstruction of a three-dimensional model of a vascular tree from two-dimensional X-ray projection images (A, B, C) that are taken from different spatial directions. On a first projection image (A) at least one reference point (CA) is specified. The gray-value profiles along the epipolar lines (EB, EC) for said reference point (CA) in other projection images (B, C) are then projected on the projection line (L) of the reference point (CA) and added there punctiformly to form a sum profile (S). The sum profile (S) has an extreme, for example, a gray-value minimum, at the position of the space point (C3D) belonging to the reference point (CA). In this way, it is possible to reconstruct semiautomatically a vascular tree from X-ray projections.

摘要翻译： 本发明涉及从不同空间方向拍摄的二维X射线投影图像（A，B，C）重建血管树的三维模型的方法。 在第一投影图像（A）上指定至少一个参考点（CA）。 然后将其他投影图像（B，C）中的所述参考点（CA）的沿着对极线（EB，EC）的灰度值分布投影到参考点（CA）的投影线（L）上并在其中添加 以形成一个总和分布（S）。 在属于参考点（CA）的空间点（C3D）的位置处，总和曲线（S）具有极端，例如灰度值最小值。 以这种方式，可以从X射线投影半自动重建血管树。

公开(公告)号：US07426256B2

公开(公告)日：2008-09-16

申请号：US10549267

申请日：2004-03-12

申请人： Volker Rasche ,  Babak Movassaghi ,  Marcel Boosten

发明人： Volker Rasche ,  Babak Movassaghi ,  Marcel Boosten

IPC分类号： A61B6/03

CPC分类号： A61B6/5264 ,  A61B6/00 ,  A61B6/503 ,  A61B6/508 ,  A61B6/541 ,  G01N23/046 ,  G01N2223/419 ,  G01N2223/612 ,  G06T11/005 ,  G06T2211/404 ,  G06T2211/412

摘要： An X-ray imaging method forms a set of a plurality of two-dimensional X-Ray projection images of a medical or veterinary object to be examined through a scanning rotation by an X-Ray source viz à viz the object. Such X-Ray images are acquired at respective predetermined time instants with respect to a functionality process produced by the object. From said set of X-Ray projection images by back-projection a three-dimensional volume image of the object is reconstructed. In particular, an appropriate motion correction is derived for the respective two-dimensional images, and subsequently as based on a motion vector field from the various corrected two-dimensional images the intended three-dimensional volume is reconstructed.

摘要翻译： X射线成像方法通过由X射线源进行扫描旋转来形成待检查的医疗或兽医物体的多个二维X射线投影图像的集合，即X射线源。 相对于由对象产生的功能处理，在相应的预定时刻获取这样的X射线图像。 通过反投影从所述X射线投影图像组中重构对象的三维体积图像。 具体地，针对相应的二维图像导出适当的运动校正，并且随后基于来自各种校正的二维图像的运动矢量场来重构预期的三维体积。

公开(公告)号：US20080218510A1

公开(公告)日：2008-09-11

申请号：US11997340

申请日：2006-07-12

申请人： Michael Grass ,  Volker Rasche ,  Dirk Schaefer

发明人： Michael Grass ,  Volker Rasche ,  Dirk Schaefer

IPC分类号： G06T15/00

CPC分类号： G06T11/005 ,  G06T2211/412

摘要： A method for generating or reconstruction of three-dimensional (3D) images corresponding to a structure of interest (60) including: acquiring a plurality of image projections corresponding to a structure of interest (60); applying a shape model (66) at a selected 3D seed point (64); and adapting the shape model (66) to represent the structure of interest (60), yielding an adapted shape model. A system for generation and reconstruction of three-dimensional (3D) images. The system (10) includes: an imaging system (12) configured to provide projection data corresponding to a structure of interest (60); and a controller (50) in operable communication with the imaging system (50). The controller (50) is configured to: receive the projection data, (64); apply a shape model (66) at a selected 3D seed point (64); and adapt the shape model (66) to represent the structure of interest (60), thereby yielding an adapted shape model.

摘要翻译： 一种用于生成或重建对应于感兴趣结构（60）的三维（3D）图像的方法，包括：获取与感兴趣结构相对应的多个图像投影（60）; 在选定的3D种子点（64）处应用形状模型（66）; 以及使形状模型（66）适应于表示感兴趣的结构（60），产生适应的形状模型。 一种用于三维（3D）图像的生成和重建的系统。 系统（10）包括：成像系统（12），被配置为提供对应于感兴趣结构（60）的投影数据; 以及与成像系统（50）可操作地通信的控制器（50）。 控制器（50）被配置为：接收投影数据（64）; 在选定的3D种子点（64）上应用形状模型（66）; 并适应形状模型（66）来表示感兴趣的结构（60），从而产生适应的形状模型。

公开(公告)号：US07400136B2

公开(公告)日：2008-07-15

申请号：US10553771

申请日：2004-04-14

申请人： Jörn Borgert ,  Volker Rasche

发明人： Jörn Borgert ,  Volker Rasche

IPC分类号： G01B7/15 ,  H01F5/00 ,  G01N27/72

CPC分类号： A61B5/061 ,  A61B5/06 ,  A61B6/12 ,  A61B6/469

摘要： Position measurements are often performed using a localization system with a given fixed capture range and accuracy and resolution. Having a fixed capture range often comes at the cost of decreased accuracy and resolution. At the start, a large capture range is provided where the accuracy and resolution is low. In this large capture area, the target area can be identified and aimed at. With this identification, a smaller capture range is iteratively provided and centered around the region of interest, which leads to an increased accuracy and resolution.

摘要翻译： 位置测量通常使用具有给定的固定捕获范围和精度和分辨率的定位系统执行。 具有固定的捕获范围通常来自降低精度和分辨率的代价。 在开始时，提供了一个大的捕获范围，其精度和分辨率低。 在这个大的捕获区域，目标区域可以被识别和瞄准。 通过这种识别，迭代地提供较小的捕获范围并以感兴趣的区域为中心，这导致增加的精度和分辨率。