公开(公告)号：US12016635B2

公开(公告)日：2024-06-25

申请号：US17330521

申请日：2021-05-26

Applicant: HeartFlow, Inc.

Inventor： Charles A. Taylor

IPC: G06T7/00 ,  A61B5/00 ,  A61B5/02 ,  A61B5/021 ,  A61B5/024 ,  A61B5/026 ,  A61B5/029 ,  A61B5/055 ,  A61B5/107 ,  A61B5/11 ,  A61B5/22 ,  A61B6/00 ,  A61B6/03 ,  A61B6/50 ,  A61B8/02 ,  A61B8/04 ,  A61B8/06 ,  A61B8/08 ,  A61B34/00 ,  A61B34/10 ,  A61M5/00 ,  G01R33/56 ,  G01R33/563 ,  G06F17/10 ,  G06F18/10 ,  G06F18/22 ,  G06F18/24 ,  G06F30/20 ,  G06F30/23 ,  G06F30/28 ,  G06G7/60 ,  G06T7/11 ,  G06T7/12 ,  G06T7/13 ,  G06T7/149 ,  G06T7/20 ,  G06T7/60 ,  G06T7/62 ,  G06T7/70 ,  G06T7/73 ,  G06T11/00 ,  G06T11/20 ,  G06T11/60 ,  G06T15/10 ,  G06T17/00 ,  G06T17/20 ,  G06V10/40 ,  G06V10/42 ,  G06V10/44 ,  G06V20/69 ,  G16B5/00 ,  G16B45/00 ,  G16H10/40 ,  G16H10/60 ,  G16H30/20 ,  G16H30/40 ,  G16H50/30 ,  G16H50/50 ,  G16H50/70 ,  G16H70/00 ,  A61B90/00 ,  G06T7/10 ,  G06V10/46

CPC classification number: A61B34/10 ,  A61B5/0035 ,  A61B5/004 ,  A61B5/0044 ,  A61B5/02 ,  A61B5/02007 ,  A61B5/02028 ,  A61B5/021 ,  A61B5/024 ,  A61B5/026 ,  A61B5/0263 ,  A61B5/029 ,  A61B5/055 ,  A61B5/1075 ,  A61B5/1118 ,  A61B5/22 ,  A61B5/4848 ,  A61B5/6852 ,  A61B5/7246 ,  A61B5/7275 ,  A61B5/7278 ,  A61B5/745 ,  A61B6/03 ,  A61B6/032 ,  A61B6/481 ,  A61B6/503 ,  A61B6/504 ,  A61B6/507 ,  A61B6/5205 ,  A61B6/5217 ,  A61B6/5229 ,  A61B8/02 ,  A61B8/04 ,  A61B8/06 ,  A61B8/065 ,  A61B8/481 ,  A61B8/5223 ,  A61B8/5261 ,  A61B34/25 ,  A61M5/007 ,  G01R33/5601 ,  G01R33/5635 ,  G01R33/56366 ,  G06F17/10 ,  G06F18/10 ,  G06F18/22 ,  G06F18/24 ,  G06F30/20 ,  G06F30/23 ,  G06F30/28 ,  G06G7/60 ,  G06T7/0012 ,  G06T7/0014 ,  G06T7/11 ,  G06T7/12 ,  G06T7/13 ,  G06T7/149 ,  G06T7/20 ,  G06T7/60 ,  G06T7/62 ,  G06T7/70 ,  G06T7/73 ,  G06T7/74 ,  G06T11/00 ,  G06T11/001 ,  G06T11/008 ,  G06T11/20 ,  G06T11/60 ,  G06T15/10 ,  G06T17/00 ,  G06T17/005 ,  G06T17/20 ,  G06V10/40 ,  G06V10/42 ,  G06V10/44 ,  G06V20/698 ,  G16B5/00 ,  G16B45/00 ,  G16H10/40 ,  G16H10/60 ,  G16H30/20 ,  G16H30/40 ,  G16H50/30 ,  G16H50/50 ,  G16H50/70 ,  G16H70/00 ,  A61B5/6868 ,  A61B2034/104 ,  A61B2034/105 ,  A61B2034/107 ,  A61B2034/108 ,  A61B2090/374 ,  A61B2090/3762 ,  A61B2090/3764 ,  A61B2576/00 ,  A61B2576/023 ,  G06T7/10 ,  G06T2200/04 ,  G06T2207/10012 ,  G06T2207/10072 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/10104 ,  G06T2207/10108 ,  G06T2207/20036 ,  G06T2207/20124 ,  G06T2207/30016 ,  G06T2207/30048 ,  G06T2207/30104 ,  G06T2210/41 ,  G06T2211/404 ,  G06V10/467 ,  Y02A90/10 ,  G06T7/0012 ,  G06T2207/30048

Abstract: Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

公开(公告)号：US12016628B2

公开(公告)日：2024-06-25

申请号：US16497071

申请日：2018-03-27

Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS

Inventor： Xincheng Yao ,  Tae Yun Son

IPC: A61B3/10 ,  A61B3/00 ,  A61B3/12 ,  G01J3/02 ,  G01J3/45 ,  G06T7/10

CPC classification number: A61B3/102 ,  A61B3/0008 ,  A61B3/0025 ,  A61B3/1241 ,  G01J3/0208 ,  G01J3/45 ,  G06T7/10 ,  G01J2003/451 ,  G06T2207/10101 ,  G06T2207/30041 ,  G06T2211/404 ,  G06T2219/021

Abstract: A multi-modal functional OCT imaging methodology and system are provided that enable concurrent intrinsic optical signal (IOS) imaging of stimulus-evoked neural activity and hemodynamic responses at capillary resolution. An OCT angiography (OCTA)-guided IOS analysis is used to separate neural-IOS and hemodynamic-IOS changes in the same retinal image sequence. The OCTA-guided IOS data processing used for this purpose differentiates two functional images, namely, a neural-IOS map and a hemodynamic-IOS map, from the same image dataset.

公开(公告)号：US11969279B2

公开(公告)日：2024-04-30

申请号：US15823031

申请日：2017-11-27

Applicant: Medtronic Navigation, Inc.

Inventor： Patrick A. Helm ,  Shuanghe Shi

IPC: A61B6/00 ,  A61B6/02 ,  A61B6/46 ,  A61B6/50 ,  A61B34/20 ,  A61M5/00 ,  G06T11/00 ,  A61B6/40

CPC classification number: A61B6/481 ,  A61B6/02 ,  A61B6/4405 ,  A61B6/4476 ,  A61B6/469 ,  A61B6/482 ,  A61B6/486 ,  A61B6/503 ,  A61B6/504 ,  A61B6/507 ,  A61B6/5288 ,  A61B6/545 ,  A61M5/007 ,  G06T11/005 ,  A61B6/4085 ,  A61B34/20 ,  A61B2576/023 ,  G01N2223/419 ,  G06T2207/10081 ,  G06T2207/30048 ,  G06T2211/404 ,  G06T2211/412

Abstract: A method and system is disclosed for acquiring image data of a subject. The image data can be collected with an imaging system having a detector able to move relative to the subject. A contrast agent can be injected into the subject and image data can be acquired with the contrast agent in various phases of the subject. A volumetric model of multiple phases can be reconstructed selected reconstruction techniques.

公开(公告)号：US11918293B2

公开(公告)日：2024-03-05

申请号：US17106987

申请日：2020-11-30

Applicant: HeartFlow, Inc.

Inventor： Leo Grady ,  Charles A. Taylor ,  Christopher Zarins

IPC: A61B34/10 ,  A61B5/026 ,  A61B6/00 ,  A61B6/03 ,  A61B8/06 ,  G06F30/20 ,  G06T7/00 ,  G06T7/11 ,  G09B9/00 ,  G09B23/30 ,  G16H50/50

CPC classification number: A61B34/10 ,  A61B5/0263 ,  A61B6/032 ,  A61B6/503 ,  A61B6/504 ,  A61B8/06 ,  G06F30/20 ,  G06T7/0012 ,  G06T7/11 ,  G09B9/00 ,  G09B23/303 ,  G16H50/50 ,  A61B2034/104 ,  A61B2034/105 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/10132 ,  G06T2207/30048 ,  G06T2207/30056 ,  G06T2207/30084 ,  G06T2207/30104 ,  G06T2211/404

Abstract: Systems and methods are disclosed for assessing organ and/or tissue transplantation by estimating blood flow through a virtual transplant model by receiving a patient-specific anatomical model of the intended transplant recipient; receiving a patient-specific anatomical model of the intended transplant donor, the model including the vasculature of the organ or tissue that is intended to be transplanted to the recipient; constructing a unified model of the connected system post transplantation, the connected system including the transplanted organ or tissue from the intended transplant donor and the vascular system of the intended transplant recipient; receiving one or more blood flow characteristics of the connected system; assessing the suitability for an actual organ or tissue transplantation using the received blood flow characteristics; and outputting the assessment into an electronic storage medium or display.

公开(公告)号：US11890125B2

公开(公告)日：2024-02-06

申请号：US17479645

申请日：2021-09-20

Applicant: Accuray, Inc.

Inventor： Jacob Shea ,  Brandon Frederick ,  Eric Schnarr ,  Daniel Gagnon

IPC: A61B6/00 ,  A61B6/02 ,  A61N5/10 ,  G06T11/00 ,  A61B6/03 ,  A61B6/06 ,  A61B6/08 ,  G06T7/30 ,  A61B6/04

CPC classification number: A61B6/5282 ,  A61B6/027 ,  A61B6/032 ,  A61B6/06 ,  A61B6/405 ,  A61B6/4078 ,  A61B6/4085 ,  A61B6/469 ,  A61B6/488 ,  A61B6/5205 ,  G06T11/005 ,  A61B6/025 ,  A61B6/03 ,  A61B6/035 ,  A61B6/0407 ,  A61B6/08 ,  A61B6/4014 ,  A61B6/4021 ,  A61B6/4028 ,  A61B6/4064 ,  A61B6/4435 ,  A61B6/4441 ,  A61B6/4458 ,  A61B6/481 ,  A61B6/482 ,  A61B6/483 ,  A61B6/484 ,  A61B6/541 ,  A61B6/582 ,  A61N5/107 ,  A61N5/1049 ,  A61N5/1067 ,  A61N5/1071 ,  A61N5/1082 ,  A61N2005/1085 ,  A61N2005/1091 ,  A61N2005/1095 ,  G06T7/30 ,  G06T11/008 ,  G06T2207/10081 ,  G06T2210/41 ,  G06T2211/404 ,  G06T2211/412 ,  G06T2211/424 ,  G06T2211/428 ,  G06T2211/432

Abstract: A multimodal imaging apparatus, comprising a rotatable gantry system positioned at least partially around a patient support, a first source of radiation coupled to the rotatable gantry system, the first source of radiation configured for imaging radiation, a second source of radiation coupled to the rotatable gantry system, the second source of radiation configured for at least one of imaging radiation or therapeutic radiation, wherein the second source of radiation has an energy level more than the first source of radiation, and a second radiation detector coupled to the rotatable gantry system and positioned to receive radiation from the second source of radiation, and a processor configured to combine first measured projection data based on the radiation detected by the first detector with second measured projection data based on the radiation detected by the second detector, and reconstruct an image based on the combined data, wherein the reconstructing comprises at least one of correcting the second measured projection data using the first measured projection data, correcting the first measured projection data using the second projection data, and distinguishing different materials imaged in the combined data using the first measured projection data and the second measured projection.

公开(公告)号：US11728037B2

公开(公告)日：2023-08-15

申请号：US17391900

申请日：2021-08-02

Applicant: CathWorks Ltd.

Inventor： Ifat Lavi ,  Ran Kornowski ,  Idit Avrahami ,  Nessi Benishti ,  Guy Lavi

IPC: G16H50/30 ,  G16H30/20 ,  G06T17/00 ,  G06T7/00 ,  A61B6/00 ,  G16H50/50 ,  A61B5/02 ,  A61B5/026 ,  A61B5/107 ,  G06T7/55 ,  A61M5/00 ,  G06T11/00 ,  A61B6/02 ,  A61B6/03 ,  A61B8/06 ,  A61B5/021 ,  A61B5/00

CPC classification number: G16H50/30 ,  A61B5/026 ,  A61B5/02007 ,  A61B5/1075 ,  A61B6/022 ,  A61B6/466 ,  A61B6/503 ,  A61B6/504 ,  A61B6/5235 ,  A61M5/007 ,  G06T7/00 ,  G06T7/0012 ,  G06T7/55 ,  G06T11/008 ,  G06T17/00 ,  G16H30/20 ,  G16H50/50 ,  A61B5/021 ,  A61B5/0263 ,  A61B5/7285 ,  A61B5/7289 ,  A61B6/02 ,  A61B6/032 ,  A61B6/037 ,  A61B6/481 ,  A61B6/507 ,  A61B6/5217 ,  A61B6/5258 ,  A61B6/541 ,  A61B8/06 ,  A61B2576/023 ,  G06T2200/04 ,  G06T2207/10072 ,  G06T2207/10116 ,  G06T2207/10132 ,  G06T2207/20044 ,  G06T2207/20072 ,  G06T2207/30101 ,  G06T2207/30104 ,  G06T2207/30172 ,  G06T2210/41 ,  G06T2211/404

Abstract: A method and apparatus for vascular assessment are disclosed. The apparatus, in some embodiments, receives a plurality of 2-D angiographic images of a portion of a vasculature of a subject, and processes the images to produce a stenotic model over the vasculature. The stenotic model has measurements of the vasculature at one or more locations along vessels of the vasculature. The apparatus, in some embodiments, determines a flow characteristic of the stenotic model and calculates an index indicative of vascular function, based, at least in part, on the flow characteristic in the stenotic model.

公开(公告)号：US20230172448A1

公开(公告)日：2023-06-08

申请号：US18077469

申请日：2022-12-08

Applicant: VICTOR X.D. YANG ,  CHAOLIANG CHEN

Inventor： VICTOR X.D. YANG ,  CHAOLIANG CHEN

IPC: A61B3/12 ,  G16H30/40 ,  A61B3/00 ,  A61B3/10 ,  A61B5/00 ,  G06T7/00 ,  G06T11/00

CPC classification number: A61B3/1233 ,  G16H30/40 ,  A61B3/0025 ,  A61B3/102 ,  A61B5/0066 ,  A61B5/489 ,  A61B5/7214 ,  G06T7/0012 ,  G06T11/008 ,  A61B2562/0233 ,  A61B2576/00 ,  G06T2207/30041 ,  G06T2207/30088 ,  G06T2210/41 ,  G06T2211/404

Abstract: Systems and methods are provided for performing optical coherence tomography angiography for the rapid generation of en face images. According to one example embodiment, differential interferograms obtained using a spectral domain or swept source optical coherence tomography system are convolved with a Gabor filter, where the Gabor filter is computed according to an estimated surface depth of the tissue surface. The Gabot-convolved differential interferogram is processed to produce an en face image, without requiring the performing of a fast Fourier transform and k-space resampling. In another example embodiment, two interferograms are separately convolved with a Gabor filter, and the amplitudes of the Gabor-convolved interferograms are subtracted to generate a differential Gabor-convolved interferogram amplitude frame, which is then further processed to generate an en face image in the absence of performing a fast Fourier transform and k-space resampling. The example OCTA methods disclosed herein are shown to

公开(公告)号：US20190094320A1

公开(公告)日：2019-03-28

申请号：US16143803

申请日：2018-09-27

Applicant: Canon Medical Systems Corporation

Inventor： Shuhei BANNAE ,  Satoshi SUGIURA

IPC: G01R33/48 ,  G01R33/56 ,  G01R33/483 ,  G06T15/08 ,  G01R33/563

CPC classification number: G01R33/4822 ,  G01R33/385 ,  G01R33/4824 ,  G01R33/4826 ,  G01R33/4833 ,  G01R33/5602 ,  G01R33/5608 ,  G01R33/5635 ,  G06T15/08 ,  G06T2211/404

Abstract: A magnetic resonance imaging apparatus according to an embodiment includes sequence controlling circuitry. The sequence controlling circuitry applies a pre-pulse that inverts longitudinal magnetization from a positive value to a negative value and is configured, when a predetermined time period has elapsed, to acquire k-space data by performing three-dimensional acquisitions in which a radial acquisition is performed on a kx-ky plane and a Cartesian acquisition is performed in a kz direction.

公开(公告)号：US20180336676A1

公开(公告)日：2018-11-22

申请号：US15597026

申请日：2017-05-16

Applicant: Siemens Healthcare GmbH

Inventor： Komal Dutta ,  Scott Baker

IPC: G06T7/00 ,  G06T11/60 ,  G06T7/187 ,  G06T7/11 ,  G06T7/13

CPC classification number: G06T7/11 ,  G06T7/187 ,  G06T7/194 ,  G06T11/60 ,  G06T2207/10116 ,  G06T2207/30101 ,  G06T2210/12 ,  G06T2211/404

Abstract: A framework for isolating an aneurysm and parent vessel in volumetric image data is provided herein. In accordance with one aspect, the framework generates a refined mask by performing region growing starting at an aneurysm dome point to eliminate vessels that are indirectly connected to an aneurysm or parent vessel in volumetric image data. A final mask may be generated based at least in part on the refined mask by eliminating any kissing vessel connected with the aneurysm from the refined mask. The final mask may then be used for segmentation of the aneurysm and the parent vessel in the volumetric image data.

公开(公告)号：US20180310888A1

公开(公告)日：2018-11-01

申请号：US15771676

申请日：2016-11-30

Applicant: Siemens Healthcare GmbH

Inventor： Lucian Mihai Itu ,  Tiziano Passerini ,  Puneet Sharma

IPC: A61B5/00 ,  G16H50/30 ,  G16H50/50 ,  A61B5/02 ,  G16H50/20

CPC classification number: A61B5/7264 ,  A61B5/0044 ,  A61B5/02007 ,  A61B5/02028 ,  A61B5/026 ,  A61B5/7267 ,  A61B6/507 ,  A61B2576/023 ,  G06F19/00 ,  G06T7/0012 ,  G06T2207/20081 ,  G06T2207/30048 ,  G06T2207/30104 ,  G06T2211/404 ,  G16H50/30 ,  G16H50/50

Abstract: A computer-implemented method for personalized assessment of patients with acute coronary syndrome (ACS) includes extracting (i) patient-specific coronary geometry data from one or more medical images of a patient; (ii) a plurality of features of a patient-specific coronary arterial tree based on the patient-specific coronary geometry data; and (iii) a plurality of ACS-related features from additional patient measurement data. A surrogate model is used to predict patient-specific hemodynamic measures of interest related to ACS based on the plurality of features of the patient-specific coronary arterial tree and the plurality of ACS-related features from the additional patient measurement data.