公开(公告)号：US20060087918A1

公开(公告)日：2006-04-27

申请号：US11301386

申请日：2005-12-13

Applicant: Hongmiao Ji ,  Victor Samper

Inventor： Hongmiao Ji ,  Victor Samper

IPC: B01F5/00 ,  B81B1/00

CPC classification number: B01F13/0059 ,  B01F5/0646 ,  B01F5/0647 ,  B01F2215/0431 ,  B01F2215/0495 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00819 ,  B01J2219/00835 ,  B01J2219/00889 ,  B01J2219/00952 ,  B01J2219/00984 ,  B01J2219/00995 ,  B01L3/5027 ,  Y10S366/03

Abstract: Microfluidics mixing apparatus and methods of using same are disclosed for mixing fluids using increasing centrifugal force as the fluids being mixed traverse a mixing channel. One inventive apparatus comprises a generally planar substrate having a top major surface and a bottom major surface generally parallel to the top major surface, and a cover plate over the top major surface. The substrate has at least one inlet port that routes fluid to the top major surface, and at least one outlet port for mixed fluid. The substrate comprises a mixing channel having a depth measured from the top surface and a width, the mixing channel adapted to route fluids to be mixed therein in laminar flow and in a substantially spiral flow pattern that is parallel to the top surface. Apparatus of the invention can mix fluids flowing serially, or two or more fluids entering the device from different feed channels.

Abstract translation: 公开了微流体混合装置及其使用方法，用于当混合的流体穿过混合通道时，使用增加的离心力混合流体。 一种本发明的装置包括具有大体上平行于顶部主表面的顶部主表面和底部主表面的大致平面的基底，以及在顶部主表面上的盖板。 衬底具有至少一个将流体输送到顶部主表面的入口端口和用于混合流体的至少一个出口端口。 衬底包括具有从顶表面测量的深度和宽度的混合通道，混合通道适于在层流中引导待混合的流体并且以与顶表面平行的基本上螺旋形的流动图案。 本发明的装置可以混合串联流动的流体，或混合从不同进料通道进入装置的两种或更多种流体。