公开(公告)号：US20060062774A1

公开(公告)日：2006-03-23

申请号：US11205984

申请日：2005-08-17

申请人： Catherine Davis ,  Thomas Osborn ,  Kenneth Miller ,  Bruce Jones

发明人： Catherine Davis ,  Thomas Osborn ,  Kenneth Miller ,  Bruce Jones

IPC分类号： A61K35/74

CPC分类号： A61Q15/00 ,  A61K8/99 ,  A61K35/741 ,  A61K35/744 ,  A61K35/747 ,  A61Q11/00 ,  C12N1/20 ,  C12R1/225 ,  A61K2300/00

摘要： A composition and methods for maintaining and restoring normal urogenital flora in humans. The composition includes one or more bacteria selected from the group consisting of Lactobacillus iners, all clones with at least 97% sequence similarity to Lactobacillus iners, Atopobium spp, and all clones with at least 90% sequence similarity to Atopobium spp as determined by sequences from 16S rRNA genes. The method for maintaining includes administering a safe and effective amount of the composition. The method for restoring includes administering a safe and effective amount of an antibiotic and subsequently administering a safe and effective amount of the composition.

摘要翻译： 用于维持和恢复人类正常泌尿生殖菌群的组合物和方法。 该组合物包括一种或多种选自乳酸杆菌的细菌，与乳杆菌属菌株具有至少97％的序列相似性的所有克隆，以及与Atopobium spp具有至少90％的序列相似性的所有克隆，所述克隆通过 16S rRNA基因。 维持方法包括施用安全有效量的组合物。 恢复方法包括施用安全有效量的抗生素并随后施用安全有效量的组合物。

公开(公告)号：US20060062773A1

公开(公告)日：2006-03-23

申请号：US11205963

申请日：2005-08-17

申请人： Catherine Davis ,  Thomas Osborn ,  Kenneth Miller ,  Bruce Jones

发明人： Catherine Davis ,  Thomas Osborn ,  Kenneth Miller ,  Bruce Jones

IPC分类号： A61K35/74

CPC分类号： A61Q15/00 ,  A61K8/99 ,  A61K35/741 ,  A61K35/744 ,  A61K35/747 ,  A61Q11/00 ,  C12N1/20 ,  C12R1/225 ,  A61K2300/00

摘要： A composition and method for maintaining and restoring normal gastrointestinal flora in humans. The composition includes one or more bacteria selected from the group consisting of Lactobacillus iners, all clones with at least 97% sequence similarity to Lactobacillus iners, Atopobium spp, and all clones with at least 90% sequence similarity to Atopobium spp as determined by sequences from 16S rRNA genes. The method for maintaining and restoring includes administering a safe and effective amount of the composition.

摘要翻译： 用于维持和恢复人类正常胃肠道菌群的组合物和方法。 该组合物包括一种或多种选自乳酸杆菌的细菌，与乳杆菌属菌株具有至少97％的序列相似性的所有克隆，以及与Atopobium spp具有至少90％的序列相似性的所有克隆，所述克隆通过 16S rRNA基因。 维持和恢复的方法包括施用安全有效量的组合物。

公开(公告)号：US20050273042A1

公开(公告)日：2005-12-08

申请号：US10861728

申请日：2004-06-04

申请人： Thomas Osborn ,  Diana Gann ,  Charles Berg ,  Jacqueline Daniels

发明人： Thomas Osborn ,  Diana Gann ,  Charles Berg ,  Jacqueline Daniels

IPC分类号： A61F13/26 ,  A61F13/20

CPC分类号： A61F13/26

摘要： A tampon applicator for positioning a tampon inside a vaginal cavity. The tampon applicator includes an outer member disposed co-axially with an inner member for insertion of the tampon into the vaginal cavity. The inner member is slidable within the outer member wherein at least 15% of a length of the tampon remains in the outer member when the inner member is fully engaged with the outer member to define a remaining portion of the tampon.

摘要翻译： 用于将棉塞定位在阴道腔内的卫生棉条敷料器。 卫生棉条施放器包括与内部构件共同设置的用于将棉塞插入阴道腔的外部构件。 内部构件可在外部构件内滑动，其中当内部构件与外部构件完全接合以限定卫生棉条的剩余部分时，棉条的长度的至少15％保留在外部构件中。

公开(公告)号：US20050197616A1

公开(公告)日：2005-09-08

申请号：US10791976

申请日：2004-03-03

申请人： Diana Gann ,  Thomas Osborn

发明人： Diana Gann ,  Thomas Osborn

IPC分类号： A61F13/26 ,  A61F13/20

CPC分类号： A61F13/26 ,  Y10S604/904

摘要： A feminine hygiene product which has a tampon and a tampon applicator. The tampon applicator has a rupturable membranous cap permanently associated with a tampon holder tube. The tampon holder tube has a hollow interior portion, an interior surface, an exterior surface, an outer perimeter, a longitudinal axis, a first end dimensioned for insertion into a vaginal cavity, and a second end positioned oppositely to the first end. The tampon is housed in a tampon holder tube within a hollow interior portion of the tampon holder tube and is substantially aligned with the tampon holder tube in a pre-expelled position. The rupturable membranous cap covers at least a portion of the tampon. During expulsion of the tampon from the tampon holder tube, the rupturable membranous cap reorients the tampon into a direction substantially non-aligned to the longitudinal axis of the tampon holder tube in the tampon's pre-expelled position.

摘要翻译： 一种女性卫生用品，其具有卫生棉条和棉条敷料器。 卫生棉条施放器具有与棉塞保持管永久关联的可破裂的膜状帽。 卫生棉条支架管具有中空的内部部分，内表面，外表面，外周边，纵向轴线，尺寸适于插入阴道腔的第一端以及与第一端相对定位的第二端。 卫生棉条被收纳在卫生栓保持管的中空内部的卫生棉条保持管中，并且在预排出位置基本上与止血塞保持管对准。 破裂性膜帽覆盖卫生棉条的至少一部分。 在棉塞从卫生棉条保持管中排出的过程中，可破裂的膜状帽将卫生棉条重新定向到卫生棉条的预先排出位置与卫生棉条保持管的纵向轴线基本不对齐的方向。

公开(公告)号：US20050003725A1

公开(公告)日：2005-01-06

申请号：US10744361

申请日：2003-12-22

申请人： Donna Hill ,  Thomas Osborn ,  Catherine Davis

发明人： Donna Hill ,  Thomas Osborn ,  Catherine Davis

IPC分类号： A61L15/18 ,  A61L15/20 ,  A61L15/46 ,  B32B27/04

CPC分类号： A61L15/18 ,  A61L15/20 ,  A61L15/46 ,  A61L2300/254 ,  A61L2300/404 ,  Y10T442/2525

摘要： An absorbent article has an absorbent material and an outer surface including an inhibitor which is partially bound to the absorbent material and substantially inhibits the colonization of bacteria within the absorbent article. An absorbent article has an absorbent material. The absorbent material has an outer surface. The absorbent article includes a pre-toxin limiting agent which is partially bound to the absorbent material and substantially retards the production of bacteria-produced toxins by the bacteria residing within the absorbent article. An absorbent article has an absorbent material. The absorbent material has an outer surface. The absorbent article includes a toxin enclosing agent. Tthe toxin enclosing agent substantially inhibits the migration of toxin outwardly from within the absorbent article towards the outer surface of the absorbent article.

摘要翻译： 吸收性物品具有吸收材料和外表面，其包含与吸收材料部分结合的抑制剂，并基本上抑制吸收制品内细菌的定居。 吸收性物品具有吸收材料。 吸收材料具有外表面。 吸收性物品包括预毒素限制剂，其被部分地结合到吸收材料上，并且基本上阻止由吸收制品中的细菌产生细菌产生的毒素。 吸收性物品具有吸收材料。 吸收材料具有外表面。 吸收性物品包括毒素封闭剂。 毒素包封剂基本上抑制毒素从吸收制品内向外朝向吸收制品的外表面迁移。

公开(公告)号：US20070232167A1

公开(公告)日：2007-10-04

申请号：US11725462

申请日：2007-03-19

申请人： Donna Hill ,  Thomas Osborn ,  Catherine Davis

发明人： Donna Hill ,  Thomas Osborn ,  Catherine Davis

IPC分类号： B32B27/04

CPC分类号： A61L15/18 ,  A61L15/20 ,  A61L15/46 ,  A61L2300/254 ,  A61L2300/404 ,  Y10T442/2525

摘要： An absorbent article has an absorbent material and an outer surface including an inhibitor which is partially bound to the absorbent material and substantially inhibits the colonization of bacteria within the absorbent article. An absorbent article has an absorbent material. The absorbent material has an outer surface. The absorbent article includes a pre-toxin limiting agent which is partially bound to the absorbent material and substantially retards the production of bacteria-produced toxins by the bacteria residing within the absorbent article. An absorbent article has an absorbent material. The absorbent material has an outer surface. The absorbent article includes a toxin enclosing agent. The toxin enclosing agent substantially inhibits the migration of toxin outwardly from within the absorbent article towards the outer surface of the absorbent article.

摘要翻译： 吸收性物品具有吸收材料和外表面，其包含与吸收材料部分结合的抑制剂，并基本上抑制吸收制品内细菌的定居。 吸收性物品具有吸收材料。 吸收材料具有外表面。 吸收性物品包括预毒素限制剂，其被部分地结合到吸收材料上，并且基本上阻止由吸收制品中的细菌产生细菌产生的毒素。 吸收性物品具有吸收材料。 吸收材料具有外表面。 吸收性物品包括毒素封闭剂。 毒素包封剂基本上抑制毒素从吸收制品内向外向吸收制品的外表面迁移。

公开(公告)号：US20070167819A1

公开(公告)日：2007-07-19

申请号：US11295280

申请日：2005-12-06

申请人： Thomas Osborn ,  Hyundae Hong ,  Donna Rene Hill ,  John Norcom

发明人： Thomas Osborn ,  Hyundae Hong ,  Donna Rene Hill ,  John Norcom

IPC分类号： A61B8/14

CPC分类号： A61B5/224 ,  A61B5/033 ,  A61B5/055 ,  A61B6/00 ,  A61B8/0858 ,  A61B8/485 ,  A61B8/486

摘要： A method for determining material properties of internal tissues of a body, the method comprising the steps of: a. providing force measuring device, b. providing an imaging means for acquiring images of deformation or displacement of tissues inside a body cavity; c. providing a calculation means for quantifying displacement of internal tissues; d. inserting at least a portion of said probe head into the body cavity; e. applying force with said probe head against an internal body tissue; f. measuring said force applied to said internal body tissue; g. acquiring images of displacement of said internal body tissue; h. calculating said displacement of said internal body tissue; and i. calculating material properties from said measured force and said calculated displacement.

摘要翻译： 一种用于确定身体的内部组织的材料性质的方法，所述方法包括以下步骤：a。 提供力测量装置，b。 提供用于获取体腔内的组织的变形或位移的图像的成像装置; C。 提供用于量化内部组织位移的计算装置; d。 将所述探针头的至少一部分插入体腔中; e。 用所述探针头抵靠内部身体组织施加力; F。 测量施加到所述内部身体组织的力; G。 获取所述内部身体组织的位移图像; H。 计算所述内部身体组织的所述位移; 和我。 从所述测量的力和所述计算的位移计算材料性质。

公开(公告)号：US20070027424A1

公开(公告)日：2007-02-01

申请号：US11190647

申请日：2005-07-27

申请人： Diana Gann ,  Thomas Osborn

发明人： Diana Gann ,  Thomas Osborn

IPC分类号： A61F13/20

CPC分类号： A61F13/263

摘要： A tampon applicator for placing a feminine hygiene tampon into a vagina which has a tampon, a tampon housing member, a cover member, and a tampon positioning member. The tampon is partially housed within the tampon housing member. The tampon extends beyond the tampon housing member. The cover member covers at least a portion of the tampon housing member. The tampon housing member is telescopically mounted within the cover member. The tampon positioning member positions the tampon within the tampon housing member. The tampon positioning member can be disposed inside the tampon housing member and can be co-axial with the tampon. The tampon positioning member can be fixedly joined to the cover member. Alternatively, the tampon positioning member can be fixedly joined to the tampon housing member.

摘要翻译： 一种用于将女性卫生棉条放置在具有棉塞，棉塞壳体构件，盖构件和棉塞定位构件的阴道中的棉条施用器。 棉塞部分地容纳在棉塞壳体部件内。 卫生棉条延伸超过棉塞外壳构件。 盖构件覆盖卫生棉条壳体构件的至少一部分。 棉塞壳体构件可伸缩地安装在盖构件内。 止血塞定位构件将卫生棉条定位在棉塞壳体构件内。 卫生棉条定位构件可以设置在卫生棉条外壳构件内部并且可以与卫生棉条同轴。 止血塞定位构件可以固定地连接到盖构件。 或者，止血塞定位构件可以固定地连接到棉塞壳体构件。

公开(公告)号：US20070016391A1

公开(公告)日：2007-01-18

申请号：US11181233

申请日：2005-07-14

申请人： Ryo Minoguchi ,  Thomas Osborn ,  Hyundae Hong ,  Steven Owens ,  Balakrishna Haridas

发明人： Ryo Minoguchi ,  Thomas Osborn ,  Hyundae Hong ,  Steven Owens ,  Balakrishna Haridas

IPC分类号： G06G7/48 ,  G06G7/58

CPC分类号： G06F17/5018 ,  G06F2217/16 ,  G06F2217/80

摘要： A computational model of the human vaginal environment is disclosed. The model comprises finite element analysis software, segmented tissue regions, at least one defined material parameter for each of said segmented tissue regions, and at least one boundary condition for each of said segmented tissue regions. At least one of the boundary conditions is subject to physiological condition changes and the model comprises computing means for manipulating the material parameters and the boundary conditions with the finite element analysis software.

摘要翻译： 披露了人类阴道环境的计算模型。 该模型包括有限元分析软件，分段组织区域，用于每个所述分割的组织区域的至少一个定义的材料参数，以及用于每个所述分割的组织区域的至少一个边界条件。 至少有一个边界条件受生理条件的改变，该模型包括用有限元分析软件来操纵材料参数和边界条件的计算装置。

公开(公告)号：US20070015994A1

公开(公告)日：2007-01-18

申请号：US11181485

申请日：2005-07-14

申请人： Hyundae Hong ,  Ryo Minoguchi ,  Thomas Osborn ,  Steven Owens ,  Balakrishna Haridas

发明人： Hyundae Hong ,  Ryo Minoguchi ,  Thomas Osborn ,  Steven Owens ,  Balakrishna Haridas

IPC分类号： A61B5/05

CPC分类号： A61B5/035 ,  A61B5/0053 ,  A61B5/055 ,  A61B5/4519 ,  A61B8/08 ,  A61B8/485

摘要： A device and method for determining location dependent biomechanical properties of internal tissues is disclosed. The device comprises an expandable probe which is insertable into an orifice of a body and into a body; a flexible conduit to conduct fluid between a fluid supply and said expandable probe; means for conducting fluid between said fluid supply and said expandable probe, said means capable of changing the volume of said expandable probe; a pressure transducer for measuring fluid pressure of said expandable probe; imaging means for detecting strain of internal tissues contacted by said expandable probe; and calculating means for determining biomechanical properties of said internal tissues.

摘要翻译： 公开了一种用于确定内部组织的位置相关生物力学性质的装置和方法。 该装置包括可扩展探针，该可扩张探针可插入主体的孔口并进入体内; 用于在流体供应和所述可扩张探针之间传导流体的柔性导管; 用于在所述流体供应和所述可扩张探针之间传导流体的装置，所述装置能够改变所述可扩张探针的体积; 用于测量所述可扩张探针的流体压力的压力传感器; 用于检测由所述可扩张探针接触的内部组织的应变的成像装置; 以及用于确定所述内部组织的生物力学性质的计算装置。