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21.发明授权Criteria for optimal electrical resynchronization derived from multipolar leads or multiple electrodes during biventricular pacing 有权在双心室起搏期间从多极引线或多个电极获得的最佳电再同步的标准公开(公告)号：US08948869B2
公开(公告)日：2015-02-03
申请号：US13464181
申请日：2012-05-04
申请人： Subham Ghosh , Robert W. Stadler
发明人： Subham Ghosh , Robert W. Stadler
CPC分类号： A61N1/3686 , A61N1/3622 , A61N1/3627 , A61N1/368 , A61N1/3684 , A61N1/371
摘要： Generally, the disclosure is directed one or more methods or systems of cardiac pacing employing a right ventricular electrode and a plurality of left ventricular electrodes. Pacing using the right ventricular electrode and a first one of the left ventricular electrodes and measuring activation times at other ones of the left ventricular electrodes. Pacing using the right ventricular electrode and a second one of the ventricular electrodes and measuring activation times at other ones of the left ventricular electrodes. Employing sums of the measured activation times to select one of the left ventricular electrodes for delivery of subsequent pacing pulses.
摘要翻译： 通常，本公开涉及使用右心室电极和多个左心室电极的一个或多个心脏起搏方法或系统。 使用右心室电极和左心室电极中的第一个进行起搏，并测量其他左心室电极的活化时间。 使用右心室电极和第二个心室电极进行起搏，并测量其他左心室电极的活化时间。 使用所测量的激活时间的总和来选择一个左心室电极用于递送随后的起搏脉冲。
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公开(公告)号：US08862212B2
公开(公告)日：2014-10-14
申请号：US13316177
申请日：2011-12-09
IPC分类号： A61B5/0402 , G06F19/00
CPC分类号： G06F19/3443 , G06F19/00 , G16H50/70
摘要： Cardiac resynchronization therapy (CRT) performance data for a number of patients in which an implantable medical device (IMD) is implanted is aggregated and reports of the aggregated data are generated, e.g., for review by organizations or individual clinicians treating the patients. In one example, a method includes collecting CRT performance data correlated to cardiac rhythm event data for a first group of patients in which an IMD configured to deliver CRT is implanted, aggregating, with a computing device, the CRT performance data correlated to the cardiac rhythm event data for a second group of patients from among the first group of patients, and generating, with the computing device, a report comprising the aggregation of the CRT performance data correlated to the cardiac rhythm event data for the second group of patients.
摘要翻译： 对植入了植入式医疗装置（IMD）的许多患者的心脏再同步治疗（CRT）性能数据进行聚合，并且生成聚合数据的报告，例如用于治疗患者的组织或个体临床医师的审查。 在一个示例中，一种方法包括收集与其中植入用于递送CRT的IMD相关的第一组患者的与心律事件数据相关的CRT性能数据，与计算设备聚合与心律相关的CRT性能数据 生成来自第一组患者的第二组患者的事件数据，并且与计算设备一起生成包括与第二组患者的心律事件数据相关的CRT性能数据的聚集的报告。
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23.发明授权Criteria for optimal electrical resynchronization derived from multipolar leads or multiple electrodes during biventricular pacing 有权在双心室起搏期间从多极引线或多个电极获得的最佳电再同步的标准公开(公告)号：US08694099B2
公开(公告)日：2014-04-08
申请号：US13464279
申请日：2012-05-04
申请人： Subham Ghosh , Robert W. Stadler
发明人： Subham Ghosh , Robert W. Stadler
IPC分类号： A61N1/00
CPC分类号： A61N1/3686 , A61N1/3622 , A61N1/3627 , A61N1/368 , A61N1/3684 , A61N1/371
摘要： Generally, the disclosure is directed one or more methods or systems of cardiac pacing employing a right ventricular electrode and a plurality of left ventricular electrodes. Pacing using the right ventricular electrode and a first one of the left ventricular electrodes and measuring activation times at other ones of the left ventricular electrodes. Pacing using the right ventricular electrode and a second one of the ventricular electrodes and measuring activation times at other ones of the left ventricular electrodes. Employing sums of the measured activation times to select one of the left ventricular electrodes for delivery of subsequent pacing pulses.
摘要翻译： 通常，本公开涉及使用右心室电极和多个左心室电极的一个或多个心脏起搏方法或系统。 使用右心室电极和左心室电极中的第一个进行起搏，并测量其他左心室电极的活化时间。 使用右心室电极和第二个心室电极进行起搏，并测量其他左心室电极的活化时间。 使用所测量的激活时间的总和来选择一个左心室电极用于递送随后的起搏脉冲。
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公开(公告)号：US08620433B2
公开(公告)日：2013-12-31
申请号：US13464228
申请日：2012-05-04
申请人： Subham Ghosh , Robert W. Stadler
发明人： Subham Ghosh , Robert W. Stadler
IPC分类号： A61N1/365
CPC分类号： A61N1/3686 , A61N1/3622 , A61N1/3627 , A61N1/368 , A61N1/3684 , A61N1/371
摘要： Generally, the disclosure is directed one or more methods or systems of cardiac pacing employing a right ventricular electrode and a plurality of left ventricular electrodes. Pacing using the right ventricular electrode and a first one of the left ventricular electrodes and measuring activation times at other ones of the left ventricular electrodes. Pacing using the right ventricular electrode and a second one of the ventricular electrodes and measuring activation times at other ones of the left ventricular electrodes. Employing sums of the measured activation times to select one of the left ventricular electrodes for delivery of subsequent pacing pulses.
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公开(公告)号：US20130218226A1
公开(公告)日：2013-08-22
申请号：US13464255
申请日：2012-05-04
申请人： Subham Ghosh , Robert W. Stadler
发明人： Subham Ghosh , Robert W. Stadler
IPC分类号： A61N1/37
CPC分类号： A61N1/3686 , A61N1/3622 , A61N1/3627 , A61N1/368 , A61N1/3684 , A61N1/371
摘要： Generally, the disclosure is directed one or more methods or systems of cardiac pacing employing a right ventricular electrode and a plurality of left ventricular electrodes. Pacing using the right ventricular electrode and a first one of the left ventricular electrodes and measuring activation times at other ones of the left ventricular electrodes. Pacing using the right ventricular electrode and a second one of the ventricular electrodes and measuring activation times at other ones of the left ventricular electrodes. Employing sums of the measured activation times to select one of the left ventricular electrodes for delivery of subsequent pacing pulses.
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公开(公告)号：US20130218224A1
公开(公告)日：2013-08-22
申请号：US13464215
申请日：2012-05-04
申请人： Subham Ghosh , Robert W. Stadler
发明人： Subham Ghosh , Robert W. Stadler
IPC分类号： A61N1/362
CPC分类号： A61N1/3686 , A61N1/3622 , A61N1/3627 , A61N1/368 , A61N1/3684 , A61N1/371
摘要： Generally, the disclosure is directed one or more methods or systems of cardiac pacing employing a right ventricular electrode and a plurality of left ventricular electrodes. Pacing using the right ventricular electrode and a first one of the left ventricular electrodes and measuring activation times at other ones of the left ventricular electrodes. Pacing using the right ventricular electrode and a second one of the ventricular electrodes and measuring activation times at other ones of the left ventricular electrodes. Employing sums of the measured activation times to select one of the left ventricular electrodes for delivery of subsequent pacing pulses.
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27.发明授权System and method for establishing episode profiles of detected tachycardia episodes 有权用于确定检测到的心动过速发作的发作概况的系统和方法公开(公告)号：US08483813B2
公开(公告)日：2013-07-09
申请号：US12826916
申请日：2010-06-30
IPC分类号： A61B5/0452
CPC分类号： A61B5/0464 , A61N1/3621 , A61N1/3962
摘要： A medical device and associated method sense a cardiac signal and initiate an arrhythmia episode detection process in response to the cardiac signal by enabling an arrhythmia detection counter to be adjusted during the detection process. Data is accumulated relating to cardiac events during the detection process. An arrhythmia episode profile is established using the accumulated data. The accumulated data includes a pattern of the adjustment of the detection counter during the detection process.
摘要翻译： 医疗装置和相关联的方法感测心脏信号，并且通过使得能够在检测过程期间调节心律失常检测计数器来响应于心脏信号而引发心律失常发作检测过程。 在检测过程中与心脏事件相关的数据被累积。 使用累积数据建立心律失常发作概况。 累积数据包括在检测处理期间检测计数器的调整的模式。
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28.发明申请LEFT-VENTRICULAR PACING SITE SELECTION GUIDED BY ELECTROGRAM MORPHOLOGY ANALYSIS 审中-公开电子形态分析指导的左心室选择选择公开(公告)号：US20130053918A1
公开(公告)日：2013-02-28
申请号：US13598815
申请日：2012-08-30
IPC分类号： A61N1/37
CPC分类号： A61N1/3627 , A61B5/04525 , A61B5/7264 , A61N1/362 , A61N1/3684 , A61N1/3686
摘要： A medical device system and associated method classify candidate pacing electrode sites for delivering pacing pulses to a patient's heart. A control unit is operatively coupled with a plurality of electrodes for controlling the delivery of the pacing pulses, and a sensing module senses a cardiac signal generated in response to the delivered pacing pulses. A processor is configured to deliver a first pacing pulse at a first timing interval to a first pacing site, determine the cardiac signal sensed in response to the delivered first pacing pulse and determine a first morphology corresponding to the determined sensed cardiac signal, compare the first morphology to a threshold morphology and adjust the first timing interval to a second timing interval different from the first timing interval in response to the comparing, and determine the optimal pacing site in response to the adjusting.
摘要翻译： 医疗器械系统和相关方法对候选起搏电极部位进行分类，以将起搏脉冲输送到患者的心脏。 控制单元与多个电极可操作地耦合，用于控制起搏脉冲的传送，并且感测模块感测响应于所输送的起搏脉冲而产生的心脏信号。 处理器被配置为以第一定时间隔将第一起搏脉冲传送到第一起搏位置，确定响应于所传送的第一起搏脉冲而感测的心脏信号，并且确定对应于所确定的感测到的心脏信号的第一形态，比较第一起搏脉冲 形态到阈值形态，并且响应于比较将第一定时间隔调整到与第一定时间隔不同的第二定时间隔，并且响应于调整确定最佳起搏位置。
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29.发明申请公开(公告)号：US20120283587A1
公开(公告)日：2012-11-08
申请号：US13462404
申请日：2012-05-02
IPC分类号： A61B5/044 , A61B5/0402
CPC分类号： A61B5/04012 , A61B5/02 , A61B5/0402 , A61B5/04085 , A61B5/044 , A61B5/0452 , A61B5/05 , A61B5/742 , A61N1/0476 , A61N1/0484 , A61N1/3627 , A61N1/3682 , A61N1/3684
摘要： Techniques for evaluating cardiac electrical dyssynchrony are described. In some examples, an activation time is determined for each of a plurality of torso-surface potential signals. The dispersion or sequence of these activation times may be analyzed or presented to provide variety of indications of the electrical dyssynchrony of the heart of the patient. In some examples, the locations of the electrodes of the set of electrodes, and thus the locations at which the torso-surface potential signals were sensed, may be projected on the surface of a model torso that includes a model heart. The inverse problem of electrocardiography may be solved to determine electrical activation times for regions of the model heart based on the torso-surface potential signals sensed from the patient.
摘要翻译： 描述了评估心脏电气不同步的技术。 在一些示例中，为多个躯干表面电位信号中的每一个确定激活时间。 可以分析或呈现这些激活时间的分散或序列以提供患者心脏的电不同步的各种指征。 在一些示例中，电极组的电极的位置以及因此感测躯干表面电位信号的位置可以投影在包括模型心脏的模型躯干的表面上。 可以基于从患者感测到的躯干表面电位信号来解决心电图的逆问题，以确定模型心脏区域的电激活时间。
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30.发明申请IMPLANTED MULTICHAMBER CARDIAC DEVICE WITH SELECTIVE USE OF RELIABLE ATRIAL INFORMATION 有权具有选择性使用可靠的信息的植入式多媒体心脏设备公开(公告)号：US20120226179A1
公开(公告)日：2012-09-06
申请号：US13038664
申请日：2011-03-02
申请人： Robert W. Stadler , Mark L. Brown
发明人： Robert W. Stadler , Mark L. Brown
IPC分类号： A61B5/0452
CPC分类号： A61N1/3622 , A61B5/046 , A61B5/0464 , A61B5/686 , A61B5/7221 , A61B5/7282 , A61N1/3704
摘要： An implantable medical device acquires a first cardiac signal in a first heart chamber and a second cardiac signal in a second heart chamber. The device determines if the first signal is unreliable. In response to determining the first signal to be unreliable, the device switches from a first cardiac arrhythmia detection mode of operation to a second cardiac arrhythmia detection mode of operation, the first detection mode requiring the use of both the first cardiac signal and the second cardiac signal and the second detection mode requiring the use of the second cardiac signal and not requiring the use of the first cardiac signal.
摘要翻译： 可植入医疗装置获取第一心室中的第一心脏信号和第二心室中的第二心脏信号。 设备确定第一个信号是否不可靠。 响应于确定第一信号不可靠，设备从第一心律失常检测操作模式切换到第二心律失常检测操作模式，第一检测模式需要使用第一心脏信号和第二心脏 信号和第二检测模式，需要使用第二心脏信号，并且不需要使用第一心脏信号。
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