公开(公告)号：US4080461A

公开(公告)日：1978-03-21

申请号：US729229

申请日：1976-10-04

Applicant: Colin C. Beard ,  John A. Edwards ,  John H. Fried

Inventor： Colin C. Beard ,  John A. Edwards ,  John H. Fried

IPC: C07D235/32 ,  A61K31/415

CPC classification number: C07D235/32

Abstract: Benzene ring substituted benzimidazole-2-carbamate derivatives represented by the formula: ##STR1## where R is a lower alkyl group having 1 to 4 carbon atoms; R.sup.1 is --SOR.sup.2, --SO.sub.2 R.sup.2, --SCN, --SR.sup.5, --OR.sup.5 or M'(CH.sub.2).sub.n MR.sup.7 where M and M' are independently O, S, ##STR2## R.sup.7 is lower alkyl having 1 to 4 carbon atoms or aryl, and n is 1-4; R.sup.2 is lower alkyl having from 1 to 6 carbon atoms, cycloalkyl having 3 to 7 carbon atoms, lower alkenyl or lower alkynyl having 3 to 6 carbon atoms, or aralkyl or aryl; andR.sup.5 is lower alkenyl, lower alkynyl, or aralkyl. The R.sup.1 substitution is at the 5(6)-position.The compounds are useful as pesticides, particularly as anthelmintic and antifungal agents.

Abstract translation: 由下式表示的苯环取代的苯并咪唑-2-氨基甲酸酯衍生物：其中R是具有1至4个碳原子的低级烷基; R1是-SOR2，-SO2R2，-SCN，-SR5，-OR5或M'（CH2）nMR7，其中M和M'独立地是O，S，R7是具有1-4个碳原子的低级烷基或芳基， n为1-4; R2是具有1至6个碳原子的低级烷基，具有3至7个碳原子的环烷基，具有3至6个碳原子的低级链烯基或低级炔基，或芳烷基或芳基; 并且R 5为低级链烯基，低级炔基或芳烷基。 R1取代为5（6）位。

公开(公告)号：US4072696A

公开(公告)日：1978-02-07

申请号：US434656

申请日：1974-01-18

Applicant: Colin C. Beard ,  John A. Edwards ,  John H. Fried

Inventor： Colin C. Beard ,  John A. Edwards ,  John H. Fried

IPC: C07C335/28 ,  C07C147/00 ,  C07C147/06 ,  C07C149/40

CPC classification number: C07C335/28

Abstract: Carbalkoxythioureidobenzene derivatives represented by the following formula: ##STR1## where R is a lower alkyl group having 1 to 4 carbon atoms; R.sup.1 is --SR.sup.2, --SOR.sup.2, --SO.sub.2 R.sup.2, --OR.sup.2, --SCN, --SC(O)NR.sup.3 R.sup.4, or --M'(CH.sub.2).sub.n MR.sup.7 where n is 1-4; R.sup.2 is lower alkyl having 1 to 6 carbon atoms, cycloalkyl having 3 to 7 carbon atoms, lower alkenyl or lower alkynyl having 3 to 6 carbon atoms, aralkyl or aryl, provided that when R.sup.1 is --SO.sub.2 R.sup.2, R.sup.2 is not aralkyl or phenyl; R.sup.3 and R.sup.4 are independently hydrogen or lower alkyl having 1 to 6 carbon atoms; Y is amino, nitro, acylamino where the acyl portion has 1 to 6 carbon atoms, --NHC(O) (CH.sub.2).sub.m COOH where m is 1-6, or --NHC(S)NHCOOR; M and M' are independently O, S or ##STR2## and R.sup.7 is lower alkyl having 1 to 4 carbon atoms or aryl. The R.sup.1 substitution is either at the 4- or 5-position.The compounds are useful as pesticides, particularly as anthelmintic and antifungal agents.

Abstract translation: 由下式表示的碳烷氧基硫代脲基苯衍生物：其中R是具有1至4个碳原子的低级烷基; R1是-SR2，-SOR2，-SO2R2，-OR2，-SCN，-SC（O）NR3R4或-M'（CH2）nMR7，其中n是1-4; R2是具有1至6个碳原子的低级烷基，具有3至7个碳原子的环烷基，具有3至6个碳原子的低级链烯基或低级炔基，芳烷基或芳基，条件是当R 1是-SO 2 R 2时，R 2不是芳烷基或苯基; R3和R4独立地是氢或具有1至6个碳原子的低级烷基; Y是酰基部分具有1-6个碳原子的氨基，硝基，酰基氨基，-NHC（O）（CH 2）m COOH，其中m是1-6，或-NHC（S）NHCOOR; M和M'独立地为O，S或，并且R 7为具有1至4个碳原子的低级烷基或芳基。 R1取代在4-或5-位。

公开(公告)号：US4031228A

公开(公告)日：1977-06-21

申请号：US669373

申请日：1976-03-22

Applicant: Colin C. Beard

Inventor： Colin C. Beard

IPC: A61K31/41 ,  C07D513/04 ,  A61K31/425 ,  A61K31/54

CPC classification number: C07D513/04 ,  A61K31/41

Abstract: Benzene ring substituted benzimidazole-2-carbamate derivatives represented by the formula: ##STR1## where R is a lower alkyl group having 1 to 4 carbon atoms; and R.sup.1 is a fused, bicyclic heterocyclic ring moiety. The R.sup.1 S-substitution is at the 5(6)-position.The compounds are useful as pesticides, particularly as anthelmintic and antifungal agents. The compounds are also useful as antiprotozoal agents, particularly against Trichomonas vaginalis.

Abstract translation: 由下式表示的苯环取代的苯并咪唑-2-氨基甲酸酯衍生物：其中R是具有1至4个碳原子的低级烷基; 并且R 1是稠合的双环杂环部分。 R1S取代位于5（6）位。

公开(公告)号：US3935209A

公开(公告)日：1976-01-27

申请号：US441222

申请日：1974-02-11

Applicant: Colin C. Beard ,  John A. Edwards ,  John H. Fried

Inventor： Colin C. Beard ,  John A. Edwards ,  John H. Fried

IPC: C07D235/32 ,  A23K1/16 ,  C07D213/64 ,  C07D213/643 ,  C07D213/70 ,  C07D233/84 ,  C07D239/38 ,  C07D241/18 ,  C07D249/12 ,  C07D277/34 ,  C07D277/36 ,  C07D333/34

CPC classification number: C07D213/643 ,  C07D213/70 ,  C07D233/84 ,  C07D239/38 ,  C07D241/18 ,  C07D249/12 ,  C07D277/34 ,  C07D277/36 ,  C07D333/34

Abstract: Benzene ring substituted benzimidazole-2-carbamate derivatives represented by the formula: ##SPC1##Where R is a lower alkyl group having 1 to 4 carbon atoms; R.sup.1 is a heterocyclic ring having 1-4 hetero atoms; and M is O, S, or ##EQU1## The R.sup.1 M-substitution is at the 5(6)-position. The compounds are useful as pesticides, particularly as anthelmintic and antifungal agents.