公开(公告)号：US08805045B2

公开(公告)日：2014-08-12

申请号：US13248309

申请日：2011-09-29

Applicant: Christoph Guetter ,  Jens Gühring ,  Marie-Pierre Jolly ,  Arne Littmann ,  Manuela Rick ,  Michaela Schmidt ,  Hui Xue

Inventor： Christoph Guetter ,  Jens Gühring ,  Marie-Pierre Jolly ,  Arne Littmann ,  Manuela Rick ,  Michaela Schmidt ,  Hui Xue

IPC: G06K9/00 ,  G06T7/00

CPC classification number: G06T7/0083 ,  G06T7/12 ,  G06T7/174 ,  G06T2207/10016 ,  G06T2207/10072 ,  G06T2207/10116 ,  G06T2207/20104 ,  G06T2207/30004

Abstract: A method for identifying a region of interest within a time sequence of images includes acquiring a time sequence of images comprising a plurality of image frames. Image segmentation is performed to segment a region of interest (ROI) from within each of the plurality of image frames of the time sequence of images. Manual edits are received for the ROI within one or more of the plurality of image frames. The manual edits are propagated to other image frames of the plurality of images. An extent to which each of the manual edits are propagated to other image frames is dependent upon a transformation function or deformation field used to propagate the manual edits and a weighing factor that is influenced by a distance in time between the other image frames and the frames that have been manually edited.

Abstract translation: 用于识别图像的时间序列内的感兴趣区域的方法包括获取包括多个图像帧的图像的时间序列。 执行图像分割以从图像的时间序列的多个图像帧的每一个内分割感兴趣区域（ROI）。 对于多个图像帧中的一个或多个中的ROI，接收手动编辑。 手动编辑被传播到多个图像的其他图像帧。 每个手动编辑传播到其他图像帧的程度取决于用于传播手动编辑的变换函数或变形字段以及受其他图像帧和帧之间的时间距离的影响的称重因子 已经被手动编辑。

公开(公告)号：US20140088899A1

公开(公告)日：2014-03-27

申请号：US14038958

申请日：2013-09-27

Applicant: Jun Liu ,  Hui Xue ,  Marcel Dominik Nickel ,  Ti-chiun Chang ,  Mariappan S. Nadar ,  Alban Lefebvre ,  Edgar Mueller ,  Qiu Wang ,  Zhili Yang ,  Nirmal Janardhanan ,  Michael Zenge

Inventor： Jun Liu ,  Hui Xue ,  Marcel Dominik Nickel ,  Ti-chiun Chang ,  Mariappan S. Nadar ,  Alban Lefebvre ,  Edgar Mueller ,  Qiu Wang ,  Zhili Yang ,  Nirmal Janardhanan ,  Michael Zenge

IPC: G01R33/24

CPC classification number: G01R33/243 ,  G01R33/246 ,  G01R33/5611

Abstract: A method for estimating a coil sensitivity map for a magnetic resonance (MR) image includes providing a matrix A of sliding blocks of a 3D image of coil calibration data, calculating a left singular matrix V∥ from a singular value decomposition of A corresponding to τ leading singular values, calculating P=V∥V∥H, calculating a matrix S that is an inverse Fourier transform of a zero-padded matrix P, and solving MHcr=(Sr)Hcr for cr, where cr is a vector of coil sensitivity maps for all coils at spatial location r, and M = ( ( 1 1 … 1 0 0 … 0 … … … 0 0 … 0 )  ( 0 0 … 0 1 1 … 1 … … … 0 0 … 0 )   …   ( 0 0 … 0 0 0 … 0 … … … 1 1 … 1 ) ) .

Abstract translation: 用于估计磁共振（MR）图像的线圈灵敏度图的方法包括提供线圈校准数据的3D图像的滑动块的矩阵A，从对应于τ的A的奇异值分解计算左奇异矩阵V∥ 计算P = V || V | H，计算作为零填充矩阵P的傅立叶逆变换的矩阵S，求解cr的MHcr =（Sr）Hcr，其中cr是线圈灵敏度的向量 对于空间位置r处的所有线圈的映射，M =（（1 1 ... 1 0 0 ... 0 ... ... 0 0 ... 0）（0 0 ... 0 1 1 ... 1 ... ... 0 0 ... 0） ...（0 0 ... 0 0 0 ... 0 ...... ... 1 1 ... 1））。

公开(公告)号：US08682054B2

公开(公告)日：2014-03-25

申请号：US13296487

申请日：2011-11-15

Applicant: Hui Xue ,  Yixun Liu ,  Christoph Guetter ,  Marie-Pierre Jolly ,  Jens Gühring

Inventor： Hui Xue ,  Yixun Liu ,  Christoph Guetter ,  Marie-Pierre Jolly ,  Jens Gühring

IPC: G06K9/00

CPC classification number: G06T7/33 ,  G06T2207/10088 ,  G06T2207/30048

Abstract: A method and system for propagation of myocardial infarction from delayed enhanced magnetic resonance imaging (DE-MRI) to cine MRI is disclosed. A reference frame is selected in a cine MRI sequence. Deformation fields are calculated within the cine MRI sequence to register the frames of the cine MRI sequence to the reference frame. A DE-MRI image having an infarction region is registered to the reference frame of the cine MRI sequence. The DE-MRI image may be registered to the infarction region using a hybrid registration algorithm that unifies both intensity and feature points into a single cost function. Infarction information in the DE-MRI image is then propagated cardiac phases of the frames in the cine MRI sequence based on the registration of the DE-MRI image to the reference frame and the plurality of deformation fields calculated within the cine MRI sequence.

Abstract translation: 公开了一种从延迟增强磁共振成像（DE-MRI）向电磁MRI传播心肌梗死的方法和系统。 在电影MRI序列中选择参考帧。 在电影MRI序列中计算变形场，以将电影MRI序列的帧注册到参考帧。 具有梗塞区域的DE-MRI图像被登记到电影MRI序列的参考帧。 可以使用将强度和特征点统一为单个成本函数的混合配准算法将DE-MRI图像登记到梗塞区域。 DE-MRI图像中的梗死信息然后基于DE-MRI图像的登记到参考帧和在电影MRI序列中计算的多个变形场，在电影MRI序列中的帧的心脏相位传播。

公开(公告)号：US20120121200A1

公开(公告)日：2012-05-17

申请号：US13291370

申请日：2011-11-08

Applicant: Christoph Guetter ,  Christophe Chefd'hotel ,  Hui Xue ,  Jens Guehring

Inventor： Christoph Guetter ,  Christophe Chefd'hotel ,  Hui Xue ,  Jens Guehring

IPC: G06K9/36

CPC classification number: G06T3/0068 ,  G06K2209/051

Abstract: A method for symmetric and inverse-consistent registration of a pair of digital images includes calculating a first update of a forward transformation of a first digital image to a second digital image from a previous update of the forward transformation and a gradient of a cost function of the first and second digital images, calculating a first update of a backward transformation of the second digital image to the first digital image from an inverse of the first update of the forward transformation, calculating a second update of the backward transformation from first update of the backward transformation and the gradient of a cost function of the second and first digital images, and calculating a second update of the forward transformation from an inverse of the second update of the backward transformation.

Abstract translation: 用于一对数字图像的对称和反向一致配准的方法包括从前向变换的先前更新和第一数字图像的成本函数的梯度计算第一数字图像向第二数字图像的正向变换的第一更新 所述第一数字图像和所述第二数字图像从所述正向变换的所述第一更新的逆算出计算所述第二数字图像向所述第一数字图像的反向变换的第一更新，从所述正向变换的所述第一更新计算所述反向变换的第二更新， 反向变换和第二和第一数字图像的成本函数的梯度，以及从反向变换的第二更新的倒数计算正向变换的第二更新。

公开(公告)号：US20120121153A1

公开(公告)日：2012-05-17

申请号：US13295416

申请日：2011-11-14

Applicant: Hui Xue ,  Saurabh Shah ,  Christoph Guetter ,  Marie-Pierre Jolly ,  Sven Zuehlsdorff ,  Jens Guehring

Inventor： Hui Xue ,  Saurabh Shah ,  Christoph Guetter ,  Marie-Pierre Jolly ,  Sven Zuehlsdorff ,  Jens Guehring

IPC: G06K9/00

CPC classification number: G06T5/50 ,  G06T5/002 ,  G06T2207/10016 ,  G06T2207/10088 ,  G06T2207/20221 ,  G06T2207/30048

Abstract: A method and system for retrospective image combination for free-breathing magnetic resonance (MR) images is disclose. A free-breathing cardiac MR image acquisition including a plurality of frames is received. A key frame is selected of the plurality of frames. A deformation field for each frame to register each frame with the key frame. A weight is determined for each pixel in each frame based on the deformation field for each frame under a minimum total deformation constraint. A combination image is then generated as a weighted average of the frames using the weight determined for each pixel in each frame.

Abstract translation: 公开了用于自由呼吸磁共振（MR）图像的回顾性图像组合的方法和系统。 接收包括多个帧的自由呼吸心脏MR图像采集。 选择多个帧中的关键帧。 每个帧的变形场用关键帧来记录每个帧。 基于每个帧在最小总变形约束下的变形场，为每个帧中的每个像素确定权重。 然后，使用为每个帧中的每个像素确定的权重，生成组合图像作为帧的加权平均。

公开(公告)号：US20120076382A1

公开(公告)日：2012-03-29

申请号：US13239530

申请日：2011-09-22

Applicant: Christoph Guetter ,  Jens Gühring ,  Marie-Pierre Jolly ,  Xiaoguang Lu ,  Hui Xue ,  Jeremy Collins ,  Peter Weale

Inventor： Christoph Guetter ,  Jens Gühring ,  Marie-Pierre Jolly ,  Xiaoguang Lu ,  Hui Xue ,  Jeremy Collins ,  Peter Weale

IPC: G06K9/00

CPC classification number: G01R33/56316

Abstract: A method for clinical parameter derivation and adaptive flow acquisition within a sequence of magnetic resonance images includes commencing an acquisition of a sequence of images. One or more landmarks are automatically detected from within one or more images of the sequence of images. The detected one or more landmarks are propagated across subsequent images of the sequence of images. A plane is fitted to the propagation of landmarks. The positions of landmarks or alternatively the position of the fitted plane within the sequence of images is used for derivation of clinical parameters such as tissue velocities and/or performing adaptive flow acquisitions to measure blood flow properties.

Abstract translation: 在磁共振图像序列内的临床参数推导和自适应流采集的方法包括开始获取图像序列。 在图像序列的一个或多个图像内自动检测一个或多个地标。 检测到的一个或多个地标在图像序列的后续图像中传播。 一个平面适合于地标的传播。 地标的位置或替代地，图像序列内的拟合平面的位置用于推导诸如组织速度的临床参数和/或执行自适应流采集以测量血流特性。