利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

70 条记录 (耗时 0.021 秒)

    Method for stimulating connective tissue growth or wound healing
    32.
    发明申请
    Method for stimulating connective tissue growth or wound healing 审中-公开
    刺激结缔组织生长或伤口愈合的方法

    公开(公告)号：US20050209136A1

    公开(公告)日：2005-09-22

    申请号：US10794392

    申请日：2004-03-08

    申请人： Ulf Eriksson ,  Marko Uutela ,  Kari Alitalo

    发明人： Ulf Eriksson ,  Marko Uutela ,  Kari Alitalo

    IPC分类号： A61K38/18 ,  C07K14/49

    CPC分类号： C07K14/49 ,  A61K38/1858

    摘要： PDGF-D, a new member of the PDGFVEGF family of growth factors, as well as the nucleotide sequence encoding it, methods for producing it, antibodies and other antagonists to it, transfected and transformed host cells expressing it, pharmaceutical compositions containing it, and uses thereof in medical and diagnostic applications, including methods for stimulating growth of a connective tissue or healing a wound in a mammal, which methods comprise administering to the mammal an effective amount of PDGF-D polypeptides or polynucleotides encoding the PDGF-D polypeptides.

    摘要翻译： PDGF-D，PDGFVEGF家族生长因子的新成员，以及编码它的核苷酸序列，其生产方法，抗体和其它拮抗剂，转染和转化的表达它的宿主细胞，含有它的药物组合物和 其用于医学和诊断应用，包括刺激结缔组织生长或愈合哺乳动物伤口的方法，该方法包括向哺乳动物施用有效量的PDGF-D多肽或编码PDGF-D多肽的多核苷酸。

    Neuropilin/growth factor complexes and uses thereof
    33.
    发明授权
    Neuropilin/growth factor complexes and uses thereof 失效
    神经蛋白/生长因子复合物及其用途

    公开(公告)号：US06515105B1

    公开(公告)日：2003-02-04

    申请号：US09421365

    申请日：1999-10-19

    申请人： Kari Alitalo ,  Ulf Eriksson ,  Birgitta Olofsson ,  Taija Makinen

    发明人： Kari Alitalo ,  Ulf Eriksson ,  Birgitta Olofsson ,  Taija Makinen

    IPC分类号： C07K100

    CPC分类号： C07K14/71 ,  C07K14/52 ,  C07K2319/00

    摘要： Complexes of a protein selected from the group consisting of VEGF-B167, VEGF-C, VEGF-D and processed VEGF-B186 and analogs thereof and the neuropilin-1 (NP-1) receptor, the extracellular domain or a ligand-binding fragment or analogue thereof; the use of such complexes in assays for growth factor proteins having substantially the same binding affinity for a cell surface receptor as VEGF-B167, VEGF-C, VEGF-D or processed VEGF-B186 and/or in promoting or antagonizing a cellular response mediated by VEGF-B167, VEGF-C, VEGF-D and/or processed VEGF-B186; and specific binding partners, e.g. antibodies, for such complexes.

    摘要翻译： 选自VEGF-B167，VEGF-C，VEGF-D和加工的VEGF-B186及其类似物的蛋白质与神经蛋白-1（NP-1）受体，细胞外结构域或配体结合片段的复合物 或其类似物; 对于对VEGF-B167，VEGF-C，VEGF-D或加工的VEGF-B186具有基本上与细胞表面受体具有相同结合亲和力的生长因子蛋白和/或促进或拮抗细胞应答介导的生长因子蛋白 通过VEGF-B167，VEGF-C，VEGF-D和/或加工的VEGF-B186; 和特异性结合配偶体，例如 抗体。

    Isolated proteins having retinol dehydrogenase activity, and which associate with retinol binding receptors
    34.
    发明授权
    Isolated proteins having retinol dehydrogenase activity, and which associate with retinol binding receptors 失效
    分离的蛋白质具有视黄醇脱氢酶活性，并与视黄醇结合受体相关

    公开(公告)号：US06399344B1

    公开(公告)日：2002-06-04

    申请号：US08937993

    申请日：1997-09-26

    申请人： Ulf Eriksson ,  Andras Simon ,  Anna Romert

    发明人： Ulf Eriksson ,  Andras Simon ,  Anna Romert

    IPC分类号： C12N904

    CPC分类号： C12N9/0006

    摘要： Isolated membrane associated proteins which have a molecular weight of from about 30 kD to about 36 kilodaltons as determined by SDS-PAGE, are disclosed. The proteins have cis retinol dehydrogenase activity, such as 9, 11 or 13 cis retinol dehydrogenase activity, or cis activity at more than one position. Other trans-retinol dehydrogenases are also disclosed. Nucleic acid molecules which code for the proteins are also disclosed.

    摘要翻译： 公开了通过SDS-PAGE测定的具有约30kD至约36千道尔顿的分离膜相关蛋白。 蛋白质具有顺式视黄醇脱氢酶活性，例如9,11或13顺式视黄醇脱氢酶活性，或多于一个位置的顺式活性。 还公开了其他反式视黄醇脱氢酶。 还公开了编码蛋白质的核酸分子。

    Isolated nucleic acid molecule which codes for a 32 KDA protein having 11-CIS retinol dehydrogenase activity, and which associates with P63, a portion of a retinol binding protein receptor
    35.
    发明授权
    Isolated nucleic acid molecule which codes for a 32 KDA protein having 11-CIS retinol dehydrogenase activity, and which associates with P63, a portion of a retinol binding protein receptor 失效
    编码具有11-CIS视黄醇脱氢酶活性的32KDA蛋白的分离的核酸分子，其与P63相结合，视黄醇结合蛋白受体的一部分

    公开(公告)号：US06280997B1

    公开(公告)日：2001-08-28

    申请号：US08729594

    申请日：1996-10-11

    申请人： Ulf Eriksson ,  Andras Simon ,  Anna Romert

    发明人： Ulf Eriksson ,  Andras Simon ,  Anna Romert

    IPC分类号： C12N1512

    CPC分类号： C12N9/0006

    摘要： In accordance with this invention, an RPE cell membrane associated protein which has a molecular weight of about 32 kd, as determined by SDS-PAGE, has been discovered. This protein, referred to an “p32,” forms an oligomeric protein complex with the previously characterized p63 protein, a component of the membrane receptor for RBP. A nucleic acid molecule which codes for the p32 protein has also been isolated and sequence analysis shows that the p32 protein belongs to the family of short chain alcohol dehydrogenases, and exhibits 11-cis retinol dehydrogenase activity, the enzyme which catalyzes conversion of 11-cis-retinol into 11-cis retinaldehyde.

    摘要翻译： 根据本发明，已经发现通过SDS-PAGE测定的具有约32kd分子量的RPE细胞膜相关蛋白。 这种称为“p32”的蛋白质与先前表征的p63蛋白形成寡聚蛋白复合物，后者是RBP膜受体的一个成分。 编码p32蛋白的核酸分子也已经被分离，序列分析显示p32蛋白属于短链醇脱氢酶家族，并且表现出11-顺式视黄醇脱氢酶活性，该酶催化11-顺式 - 维甲酸变为11-顺式视黄醛。

    Steering wheel arrangement
    38.
    发明授权
    Steering wheel arrangement 有权
    方向盘布置

    公开(公告)号：US08117940B2

    公开(公告)日：2012-02-21

    申请号：US12091755

    申请日：2005-10-28

    申请人： Björn Andersson ,  Hassan Omarain ,  Andreas Alvehav ,  Thomas Paulsson ,  Hans Fredriksson ,  Ulf Eriksson ,  Pentti Hyvönen

    发明人： Björn Andersson ,  Hassan Omarain ,  Andreas Alvehav ,  Thomas Paulsson ,  Hans Fredriksson ,  Ulf Eriksson ,  Pentti Hyvönen

    IPC分类号： B62D1/18 ,  B62D1/16 ,  B64C13/30

    CPC分类号： B62D1/18 ,  B62D1/184 ,  B62D1/187 ,  Y10T74/20414

    摘要： A steering wheel arrangement for a motor vehicle includes a steering column having a first end for cooperation with a steering wheel and a second end for cooperation with a vehicle steering mechanism. The steering wheel arrangement further includes a suspension arrangement for the steering column. The suspension arrangement includes two pivot joints and is pivotally connected to the steering column via a third pivot joint, the first, second and third pivot joints including first, second and third locking arrangements, respectively. The steering wheel arrangement has thus three adjustable pivot points where only one or two of the three pivot joints are adjustable in a first step depressing a foot pedal to a first position and only the remaining of the three pivot joints are adjustable in a second step depressing the foot pedal to a second position which implies that the adjustments can be made in a secure way by the driver during the ride.

    摘要翻译： 用于机动车辆的方向盘装置包括转向柱，其具有用于与方向盘配合的第一端和用于与车辆转向机构配合的第二端。 方向盘装置还包括用于转向柱的悬挂装置。 悬挂装置包括两个枢转接头，并经由第三枢转接头枢转地连接到转向柱，第一，第二和第三枢转接头分别包括第一，第二和第三锁定装置。 因此，方向盘装置具有三个可调枢轴点，其中三个枢轴接头中只有一个或两个在第一步骤中可调节，第一步骤将脚踏板压下到第一位置，并且只有剩余的三个枢转接头在第二阶段压下 脚踏板到第二位置，这意味着驾驶员可以在驾驶期间以安全的方式进行调节。

    Cleaning device, cleaning tool and method of using the cleaning device
    39.
    发明授权
    Cleaning device, cleaning tool and method of using the cleaning device 失效
    清洁装置，清洁工具和使用清洁装置的方法

    公开(公告)号：US07992503B2

    公开(公告)日：2011-08-09

    申请号：US12314354

    申请日：2008-12-09

    申请人： Ulf Eriksson ,  Pär Åke Jansson

    发明人： Ulf Eriksson ,  Pär Åke Jansson

    IPC分类号： F23B99/00 ,  F22B37/48

    CPC分类号： D21C11/106

    摘要： The present invention relates to a method of using a cleaning device for cleaning outlet ports (11) or the like and/or outlet spouts (12) or the like in soda recovery boilers (13) or the like, the cleaning device comprising at least one connecting rod (9). The cleaning device has at least one front tool part (1a-d, 3, 6), mounted on said connecting rod (9).

    摘要翻译： 本发明涉及一种使用清洁装置清洗苏打水回收锅炉（13）等中的出口（11）等和/或出口喷口（12）等的方法，该清洁装置至少包括 一个连杆（9）。 清洁装置具有安装在所述连杆（9）上的至少一个前工具部分（1a-d，3,6）。

    REGULATION OF FATTY ACID TRANSPORTERS
    40.
    发明申请
    REGULATION OF FATTY ACID TRANSPORTERS 审中-公开
    脂肪酸运输机的调控

    公开(公告)号：US20110150900A1

    公开(公告)日：2011-06-23

    申请号：US12937164

    申请日：2009-04-08

    申请人： Ulf Eriksson

    发明人： Ulf Eriksson

    IPC分类号： A61K39/395 ,  A61K31/713 ,  A61P3/00 ,  G01N33/53

    CPC分类号： C07K16/22 ,  A61K2039/505 ,  C07K2317/76

    摘要： The present invention provides materials and methods for modulating FATP expression and/or activity in vivo. The materials and methods have numerous diagnostic, prophylactic, and therapeutic applications for various diseases and conditions that are influenced by FATPs, or characterized by excessive or inadequate FATP expression or activity.

    摘要翻译： 本发明提供了用于在体内调节FATP表达和/或活性的材料和方法。 这些材料和方法对于受FATP影响的各种疾病和病症具有许多诊断，预防和治疗应用，或者由于过度或不足的FATP表达或活性。