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    Manually adjustable intraocular flow regulation
    31.
    发明授权
    Manually adjustable intraocular flow regulation 有权

    公开(公告)号：US11246753B2

    公开(公告)日：2022-02-15

    申请号：US15807503

    申请日：2017-11-08

    Applicant: AqueSys, Inc.

    Inventor： Christopher Horvath ,  Laszlo O. Romoda ,  Michael Robinson

    IPC: A61F9/007

    Abstract: An implanted intraocular shunt can be manually manipulated, without surgical intervention, to modify the flow resistance of the shunt, thereby providing relief from high intraocular pressure while avoiding hypotony. For example, through application of pressure along a surface of the eye, a portion of the shunt can be displaced or separated relative to the shunt, thereby decreasing a flow resistance of the shunt.

    Intraocular shunt inserter
    32.
    发明授权
    Intraocular shunt inserter 有权

    公开(公告)号：US11135089B2

    公开(公告)日：2021-10-05

    申请号：US15917541

    申请日：2018-03-09

    Applicant: AqueSys, Inc.

    Inventor： Laszlo O. Romoda ,  Christopher Horvath

    IPC: A61F9/007

    Abstract: A system for deploying an intraocular shunt can include an intraocular shunt inserter and a deflector component that is releasable attachable to a distal end portion of the inserter. The inserter can include a housing having a distal end portion and a needle extending from the distal end portion. The deflector component can have a needle guide configured to receive the needle of the inserter therein. The deflector component can be coupled to the inserter in order to permit the needle guide to bend the needle and maintain the needle in a bended configuration.

    Intraocular shunt implantation
    33.
    发明授权
    Intraocular shunt implantation 有权

    公开(公告)号：US10369048B2

    公开(公告)日：2019-08-06

    申请号：US15703802

    申请日：2017-09-13

    Applicant: AqueSys, Inc.

    Inventor： Christopher Horvath ,  Laszlo O. Romoda ,  Richard A. Lewis

    IPC: A61F9/00 ,  A61F9/007

    Abstract: Implanting an intraocular shunt into an eye can involve creating an opening in the cornea and positioning a shunt in the anterior chamber of the eye such that the shunt terminates between layers of Tenon's capsule, thereby facilitating fluid flow out of the anterior chamber into a space between the layers of Tenon's capsule.

    Methods for intraocular shunt placement
    34.
    发明授权
    Methods for intraocular shunt placement 有权

    公开(公告)号：US10307293B2

    公开(公告)日：2019-06-04

    申请号：US15150063

    申请日：2016-05-09

    Applicant: AqueSys, Inc.

    Inventor： Christopher Horvath ,  Laszlo O. Romoda ,  Richard A. Lewis

    IPC: A61F9/007 ,  A61F2/95 ,  A61F2/966 ,  A61F9/00 ,  A61F9/008

    Abstract: Intraocular pressure can be reduced by insertion of an intraocular shunt in the eye such that it forms a drainage pathway between the anterior chamber and a region of lower pressure. A hollow shaft that holds an intraocular shunt can be advanced through the anterior chamber. The sclera can be penetrated with the hollow shaft. A beveled tip of the shaft can be oriented such that a beveled surface thereof faces toward the Tenon's capsule when the beveled tip passes out of the sclera. After the beveled tip passes out of the sclera, at least a portion of the shunt can be advanced from the hollow shaft.

    Intraocular shunt delivery
    35.
    发明授权
    Intraocular shunt delivery 有权

    公开(公告)号：US10004638B2

    公开(公告)日：2018-06-26

    申请号：US15005983

    申请日：2016-01-25

    Applicant: AqueSys, Inc.

    Inventor： Laszlo O. Romoda ,  Christopher Horvath

    IPC: A61F9/007 ,  A61F9/00

    Abstract: An intraocular shunt deployment device can release an intraocular shunt into an eye using a deployment mechanism that coordinates action between a pusher component, a shaft component, and a housing of the device. The deployment mechanism causes axial movement of the components in response to a rotational input force.

    Intraocular shunt inserter
    36.
    发明授权
    Intraocular shunt inserter 有权
    眼内分流插入器

    公开(公告)号：US09585790B2

    公开(公告)日：2017-03-07

    申请号：US14541070

    申请日：2014-11-13

    Applicant: AqueSys, Inc.

    Inventor： Christopher Horvath ,  Laszlo O. Romoda ,  Iqbal K. Ahmed ,  Brian Scott Hamstrom ,  Wesley Anne Jung ,  Vanessa I. Vera ,  Ronald D. Bache

    IPC: A61F9/007 ,  A61M5/32

    CPC classification number: A61F9/00781 ,  A61B90/02 ,  A61F9/0008 ,  A61F9/0017 ,  A61M5/3286 ,  A61M2210/0612

    Abstract: An inserter for treating glaucoma can comprise a housing, a needle, a plunger, a slider component, and a drive component. The drive component is disposed within a cavity of the housing and rotatable within the cavity to result in movement along a longitudinal axis of the inserter to the needle and the plunger upon rotation of the drive component. The slider component is coupled to the housing and slidable along an elongate groove of the drive component such that movement of the slider component along the axis rotates the drive component within the housing.

    Abstract translation: 用于治疗青光眼的插入器可以包括壳体，针，柱塞，滑块部件和驱动部件。 驱动部件设置在壳体的空腔内并且可在空腔内旋转，以在驱动部件旋转时导致沿着插入器的纵向轴线移动到针头和柱塞。 滑块部件联接到壳体并且可以沿着驱动部件的细长凹槽滑动，使得滑块部件沿轴线的运动使驱动部件在壳体内旋转。

    Methods for intraocular shunt placement
    37.
    发明授权
    Methods for intraocular shunt placement 有权
    眼内并发放置方法

    公开(公告)号：US09393153B2

    公开(公告)日：2016-07-19

    申请号：US14476503

    申请日：2014-09-03

    Applicant: AqueSys, Inc.

    Inventor： Christopher Horvath ,  Laszlo O. Romoda ,  Richard A. Lewis

    IPC: A61F9/007 ,  A61F2/95 ,  A61F2/966 ,  A61F9/00 ,  A61F9/008

    CPC classification number: A61F9/00781 ,  A61F2/95 ,  A61F2/966 ,  A61F9/00 ,  A61F9/0017 ,  A61F9/00709 ,  A61F9/00736 ,  A61F9/008

    Abstract: Intraocular pressure can be reduced by insertion of an intraocular shunt in the eye such that it forms a drainage pathway between the anterior chamber and a region of lower pressure. A hollow shaft can be advanced through the anterior chamber with the hollow shaft (a) having a beveled tip at a distal end of the hollow shaft and (b) holding an intraocular shunt with a proximal end of the shunt within the hollow shaft. The sclera can be penetrated with the hollow shaft. A beveled surface of the beveled tip can be oriented such that the beveled surface faces toward the Tenon's capsule when the beveled tip passes out of the sclera. After the beveled tip passes out of the sclera, at least a portion of the shunt can be advanced from the hollow shaft.

    Abstract translation: 可以通过在眼睛中插入眼内分流来减少眼压，使得其在前房和低压区域之间形成排水路径。 中空轴可以前进穿过前房，空心轴（a）在中空轴的远端具有斜切的尖端，以及（b）在中空轴内保持具有分流器的近端的眼内分路。 巩膜可以用空心轴穿透。 倾斜尖端的斜面可以被定向成使得当斜面尖端超出巩膜时，倾斜的表面面向Tenon的胶囊。 在斜面尖端从巩膜外出来之后，分流器的至少一部分可以从空心轴推进。

    Adjustable glaucoma implant
    40.
    发明授权
    Adjustable glaucoma implant 有权
    可调青光眼植入物

    公开(公告)号：US09125723B2

    公开(公告)日：2015-09-08

    申请号：US13771012

    申请日：2013-02-19

    Applicant: AqueSys, Inc.

    Inventor： Christopher Horvath ,  Laszlo O. Romoda ,  Brian Hamstrom ,  Ronald D. Bache ,  Guenther Grabner ,  Herbert A. Reitsamer

    IPC: A61F9/007 ,  A61F9/008 ,  A61M27/00 ,  A61F9/00

    CPC classification number: A61F9/00781 ,  A61F9/0017 ,  A61F9/007 ,  A61F9/00736 ,  A61F2009/00891 ,  A61M27/002 ,  A61M2210/0612

    Abstract: Methods and devices for adjusting or configuring the flow rate of an intraocular shunt are provided whereby hypotony can be avoided by increasing the flow rate through the device. In some embodiments, the device is a shunt that can have a first flow that can be modified to a second flow by modifying the shunt, such as by cutting the shunt. Additionally, one or more dissolvable portions can be present to provide an initial flow restriction and subsequent increase in flow over time.

    Abstract translation: 提供了用于调节或配置眼内分流器的流速的方法和装置，通过增加通过装置的流速可以避免低血压。 在一些实施例中，该装置是可以具有第一流的分流器，其可以通过修改分流器而被修改为第二流量，例如通过切断分流器。 另外，可以存在一个或多个可溶解部分以提供初始流动限制并随后随着流量的增加。

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