公开(公告)号：US10299998B2

公开(公告)日：2019-05-28

申请号：US15352669

申请日：2016-11-16

Applicant: Colgate-Palmolive Company

Inventor： Lin Fei ,  Suman Chopra ,  Prakasarao Mandadi

IPC: A61K8/19 ,  A61K8/22 ,  A61K8/23 ,  A61K8/24 ,  A61K8/46 ,  A61K8/86 ,  A61Q11/00

Abstract: Provided is a single phase oral care composition having a whitening agent; a first abrasive selected from calcium pyrophosphate, calcium carbonate, and dicalcium phosphate; a second abrasive that may include sodium metaphosphate; an anticalculus agent; and a substantially anhydrous carrier that may include an ethylene oxide/propylene oxide copolymer. In the composition, a wt % of the second abrasive is equal to or greater than a wt % of the first abrasive.

公开(公告)号：US20180333346A1

公开(公告)日：2018-11-22

申请号：US15900346

申请日：2018-02-20

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Lynette A. Zaidel ,  Guisheng Pan ,  Suman K. Chopra ,  Prakasarao Mandadi ,  Michael Prencipe

IPC: A61K8/81 ,  A61Q11/02 ,  A61Q11/00 ,  A61K8/891 ,  A61K8/90 ,  A61K8/02 ,  A61K8/49 ,  A61K8/24 ,  A61K8/22

Abstract: Oral care compositions comprising:(a) a peroxide complex comprising a peroxide component and an N-vinyl heterocyclic polymer (e.g., poly-N-vinyl polylactam, or poly-N-vinyl-polyimide);(b) a whitening agent (e.g., hydrogen peroxide); and(c) an orally acceptable carrier.In one embodiment, the carrier comprises a film forming material. Methods are also provided for making an oral care composition comprising:(a) mixing a whitening agent, silicone adhesive and carrier fluid to form a homogenous mixture;(b) adding a peroxide complex to said homogenous mixture, wherein said complex comprises hydrogen peroxide and an N-vinyl heterocyclic polymer; and(c) mixing under vacuum.

公开(公告)号：US10052270B2

公开(公告)日：2018-08-21

申请号：US14651655

申请日：2012-12-14

Applicant: Colgate-Palmolive Company

Inventor： Michael Prencipe ,  Prakasarao Mandadi ,  Olivier Garot

IPC: A61K8/22 ,  A61Q11/00 ,  A61K8/86 ,  A61K31/79 ,  A61K8/24 ,  A61K8/81 ,  A61K8/25 ,  A61K8/34

CPC classification number: A61K8/22 ,  A61K8/24 ,  A61K8/25 ,  A61K8/345 ,  A61K8/8176 ,  A61K8/86 ,  A61K2800/28 ,  A61K2800/57 ,  A61Q11/00

Abstract: Described herein are oral care compositions comprising (i) a peroxide whitening agent comprising a whitening complex of crosslinked polyvinylpyrrolidone complexed with hydrogen peroxide, (ii) sodium acid pyrophosphate (Na2H2P2O7) in an amount of from 0.05 wt % to 5 wt % based on the weight of the composition, and (iii) less than 3 wt % water based on the weight of the composition.

公开(公告)号：US09498425B2

公开(公告)日：2016-11-22

申请号：US14868469

申请日：2015-09-29

Applicant: Colgate-Palmolive Company

Inventor： Suman Chopra ,  Dennis Ontumi ,  Prakasarao Mandadi ,  Venda Maloney

IPC: A61K8/81 ,  A61Q11/00 ,  A61K8/22 ,  A61K8/24 ,  A61K8/86

CPC classification number: A61K8/8182 ,  A61K8/0216 ,  A61K8/22 ,  A61K8/24 ,  A61K8/345 ,  A61K8/463 ,  A61K8/8176 ,  A61K8/86 ,  A61K8/90 ,  A61K2800/28 ,  A61K2800/31 ,  A61K2800/52 ,  A61K2800/57 ,  A61K2800/87 ,  A61Q11/00

Abstract: Described herein are oral care compositions comprising a crosslinked polyvinylpyrrolidone complexed with hydrogen peroxide, together with particular co-polymers as additional excipients; including some embodiments which further comprise a calcium abrasive.

Abstract translation: 本文描述的是包含与过氧化氢络合的交联的聚乙烯吡咯烷酮以及特定共聚物作为其它赋形剂的口腔护理组合物; 包括进一步包含钙磨料的一些实施方案。

公开(公告)号：US20150320669A1

公开(公告)日：2015-11-12

申请号：US14651143

申请日：2012-12-14

Applicant: Colgate-Palmolive Company

Inventor： Lin Fei ,  Prakasarao Mandadi ,  Suman Chopra ,  Michael Prencipe

IPC: A61K8/81 ,  A61K8/25 ,  A61Q11/00 ,  A61K8/22

CPC classification number: A61K8/25 ,  A61K8/22 ,  A61K8/8176 ,  A61K2800/48 ,  A61Q11/00

Abstract: Described herein are oral care compositions (for tooth whitening) comprising a thickening system comprising a first thickening agent and a second thickening agent, wherein the first thickening agent comprises greater than 15 wt % of the mixture of the first and second thickening agents in the thickening system. The compositions comprise crosslinked polyvinylpyrrolidone complexed with hydrogen peroxide with a thickening system comprising silica and crosslinked polyvinylpyrrolidone.

Abstract translation: 本文描述的是含有包含第一增稠剂和第二增稠剂的增稠体系的口腔护理组合物（用于牙齿增白），其中第一增稠剂包含大于15wt％的第一和第二增稠剂在增稠中的混合物 系统。 组合物包含与过氧化氢络合的交联聚乙烯吡咯烷酮与包含二氧化硅和交联的聚乙烯吡咯烷酮的增稠体系。

公开(公告)号：US09155688B2

公开(公告)日：2015-10-13

申请号：US14366356

申请日：2012-12-18

Applicant: Colgate-Palmolive Company

Inventor： Thomas Boyd ,  Dennis Ontumi ,  Prakasarao Mandadi ,  Suman Chopra ,  Jason Nesta ,  Paloma Pimenta

IPC: A61K8/89 ,  A61K8/22 ,  A61K8/81 ,  A61Q11/00 ,  A61K8/38 ,  A61K8/891

CPC classification number: A61K8/22 ,  A61K8/38 ,  A61K8/8176 ,  A61K8/891 ,  A61K2800/872 ,  A61Q11/00

Abstract: Described herein are whitening compositions comprising a peroxide source, and an adhesion system comprising a hydrophobic component comprising a silicone adhesive; and a dental surface adhesion enhancing agent, which are physically stable and effectively provide whitening. Methods of making and using these compositions are also described herein.

Abstract translation: 本文描述的是包含过氧化物源的增白组合物和包含含有硅氧烷粘合剂的疏水组分的粘合体系; 和牙科表面粘附增强剂，其物理稳定并有效地提供美白。 本文还描述了制备和使用这些组合物的方法。