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69 条记录 (耗时 0.054 秒)

    Sustained release intraocular implants and related methods
    31.
    发明授权
    Sustained release intraocular implants and related methods 有权
    持续释放眼内植入物及相关方法

    公开(公告)号：US08962009B2

    公开(公告)日：2015-02-24

    申请号：US13840535

    申请日：2013-03-15

    申请人： Glenn T. Huang ,  Thierry Nivaggioli

    发明人： Glenn T. Huang ,  Thierry Nivaggioli

    IPC分类号： A61F2/14 ,  A61K9/00 ,  A61K31/573 ,  A61K45/06 ,  A61K31/58

    CPC分类号： A61K9/0051 ,  A61K9/0092 ,  A61K31/573 ,  A61K31/58 ,  A61K45/06 ,  A61K2300/00

    摘要： Biocompatible intraocular implants include a steroid and a polymer associated with each other to facilitate release of the steroid into an eye for a period of time greater than about two months. The steroid may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. Or, the steroid may be associated with a polymeric coating having one or more openings effective to permit the steroid to be released into an external environment. The implants may be placed in an eye to treat one or more ocular conditions. The steroid is released from the implant for more than about two months, and may be release for more than several years.

    摘要翻译： 生物相容性眼内植入物包括彼此相关的类固醇和聚合物，以促进类固醇进入眼睛大于约两个月的时间。 类固醇可以与可生物降解的聚合物基质相关联，例如两种可生物降解聚合物的基质。 或者，类固醇可以与具有一个或多个开口有效以允许类固醇释放到外部环境中的聚合物涂层相关联。 植入物可以放置在眼睛中以治疗一种或多种眼睛状况。 类固醇从植入物中释放超过约两个月，可能会释放超过几年。

    Sustained release intraocular implants and related methods
    33.
    发明授权
    Sustained release intraocular implants and related methods 有权

    公开(公告)号：US08440216B2

    公开(公告)日：2013-05-14

    申请号：US13613636

    申请日：2012-09-13

    申请人： Glenn T. Huang ,  Thierry Nivaggioli

    发明人： Glenn T. Huang ,  Thierry Nivaggioli

    IPC分类号： A61F2/14

    CPC分类号： A61K9/0051 ,  A61K9/0092 ,  A61K31/573 ,  A61K31/58 ,  A61K45/06 ,  A61K2300/00

    摘要： Biocompatible intraocular implants include a steroid and a polymer associated with each other to facilitate release of the steroid into an eye for a period of time greater than about two months. The steroid may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. Or, the steroid may be associated with a polymeric coating having one or more openings effective to permit the steroid to be released into an external environment. The implants may be placed in an eye to treat one or more ocular conditions. The steroid is released from the implant for more than about two months, and may be release for more than several years.

    Sustained release intraocular implants and methods for treating ocular neuropathies
    38.
    发明申请
    Sustained release intraocular implants and methods for treating ocular neuropathies 审中-公开
    持续释放眼内植入物和治疗眼神经病变的方法

    公开(公告)号：US20050244458A1

    公开(公告)日：2005-11-03

    申请号：US10836880

    申请日：2004-04-30

    申请人： Glenn Huang ,  Thierry Nivaggioli

    发明人： Glenn Huang ,  Thierry Nivaggioli

    IPC分类号： A61K9/00 ,  A61K31/537 ,  A61K31/138

    CPC分类号： A61K9/0051 ,  A61K31/5377

    摘要： Biocompatible intraocular implants include a beta adrenergic receptor antagonist and a polymer associated with the beta adrenergic receptor antagonist to facilitate release of the beta adrenergic receptor antagonist into an eye for an extended period of time. The beta adrenergic receptor antagonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. The implants may be placed in an eye to treat one or more ocular conditions, such as an ocular neuropathies, for example, various forms of glaucoma.

    摘要翻译： 生物相容性眼内植入物包括β-肾上腺素能受体拮抗剂和与β-肾上腺素能受体拮抗剂相关的聚合物，以促进β肾上腺素能受体拮抗剂延长一段时间的眼睛释放。 β肾上腺素能受体拮抗剂可以与可生物降解的聚合物基质例如两种可生物降解聚合物的基质相关联。 植入物可以放置在眼睛中以治疗一种或多种眼部病症，例如眼部神经病，例如各种形式的青光眼。

    Alginate and gellan gum as tablet coating
    39.
    发明授权
    Alginate and gellan gum as tablet coating 有权
    海藻酸盐和结冷胶，作为片剂包衣

    公开(公告)号：US06326028B1

    公开(公告)日：2001-12-04

    申请号：US09183238

    申请日：1998-10-30

    申请人： Thierry Nivaggioli ,  George Colegrove ,  John Flanagan

    发明人： Thierry Nivaggioli ,  George Colegrove ,  John Flanagan

    IPC分类号： A61K928

    摘要： This invention relates to coatings employed to coat medicinal tablets. Such tablets include but are not limited to small pellet(s) of medication to be taken orally. In particular this invention relates to the use of alginates and/or gellan gum, mixtures thereof and the like as tablet coatings. More in particular, this invention relates to the use of alginate and gellan gum as tablet coatings for tablets which are useful for humans including coating(s) on medicinal tablets and to a process for making such coatings.

    摘要翻译： 本发明涉及用于涂敷药片的涂层。 这样的片剂包括但不限于要口服的小丸剂。 特别地，本发明涉及藻酸盐和/或结冷胶，其混合物等作为片剂包衣的用途。 更具体地，本发明涉及藻酸盐和结冷胶胶作为片剂的片剂包衣，其可用于人，包括药用片剂上的包衣和制备这种包衣的方法。