中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

47 records (took 0.037 seconds)

    Biodegradable alpha-2 agonist polymeric implants and therapeutic uses thereof
    1.
    发明授权
    Biodegradable alpha-2 agonist polymeric implants and therapeutic uses thereof 有权
    可生物降解的α-2激动剂聚合物植入物及其治疗用途

    公开(公告)号：US09095506B2

    公开(公告)日：2015-08-04

    申请号：US12272548

    申请日：2008-11-17

    Applicant: Lon T. Spada ,  Alazar N. Ghebremeskel ,  Michael R. Robinson

    Inventor： Lon T. Spada ,  Alazar N. Ghebremeskel ,  Michael R. Robinson

    IPC: A61K9/00 ,  A61K31/498 ,  A61K47/34

    CPC classification number: A61K9/0051 ,  A61K31/498 ,  A61K47/34

    Abstract: Biocompatible intraocular implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2 adrenergic receptor agonist into an eye for an extended period of time. The alpha-2 adrenergic receptor agonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. The implants can be placed in an eye to treat one or more ocular conditions, such as an ocular vasculopathy or glaucoma, including reduction of an elevated intraocular pressure.

    Abstract translation: 生物相容性眼内植入物包括α-2肾上腺素能受体激动剂和与α-2肾上腺素能受体激动剂相关的聚合物，以促进α-2肾上腺素能受体激动剂延长一段时间的眼睛释放。 α-2肾上腺素能受体激动剂可以与可生物降解的聚合物基质例如两种可生物降解的聚合物的基质相关联。 植入物可以放置在眼睛中以治疗一种或多种眼部病症，例如眼睛血管病变或青光眼，包括降低眼内压升高。

    Pressure-sensitive adhesives and self-adhesive postage stamps made therewith
    8.
    发明授权
    Pressure-sensitive adhesives and self-adhesive postage stamps made therewith 失效
    压敏粘合剂和自粘邮票

    公开(公告)号：US06293037B1

    公开(公告)日：2001-09-25

    申请号：US09319295

    申请日：1999-09-22

    Applicant: Lon T. Spada ,  Carol A. Koch ,  Kathleen M. Alpaugh

    Inventor： Lon T. Spada ,  Carol A. Koch ,  Kathleen M. Alpaugh

    IPC: G09F310

    CPC classification number: C09J133/08 ,  C08F220/18 ,  C09J4/00 ,  Y10T428/31797 ,  Y10T428/31895 ,  Y10T428/31917

    Abstract: Acrylic, self-adhesive postage stamps are provided and include a flexible facestock bearing an acrylic pressure-sensitive adhesive (PSA), protected by a release liner. The acrylic PSA is a tackified or inherently tacky polymer formed from a plurality of monomers comprising, based on the total weight of monomeric composition, essentially of (i) 9 to 40% isobornyl acrylate and (ii) 50 to 91% of one or more alkyl acrylates.

    Abstract translation: 提供丙烯酸，自粘邮票，并且包括一个由释放衬垫保护的丙烯酸压敏粘合剂（PSA）的柔性面材。 丙烯酸PSA是由多个单体形成的增粘或固有的粘性聚合物，其包含基于单体组合物的总重量，基本上由（i）9至40％的丙烯酸异冰片酯和（ii）50至91％的一种或多种 丙烯酸烷基酯。

    Pressure sensitive adhesives of acetoacetoxy-alkyl acrylate polymers
    9.
    发明授权
    Pressure sensitive adhesives of acetoacetoxy-alkyl acrylate polymers 失效
    乙酰乙酰氧基 - 丙烯酸烷基酯聚合物的压敏粘合剂

    公开(公告)号：US5122567A

    公开(公告)日：1992-06-16

    申请号：US728820

    申请日：1991-07-08

    Applicant: Lon T. Spada ,  Joseph J. Wilczynski

    Inventor： Lon T. Spada ,  Joseph J. Wilczynski

    IPC: C08F220/12 ,  C09J7/02 ,  C09J157/04

    CPC classification number: C09J157/04 ,  C08F220/12 ,  C09J7/021 ,  C09J7/0217 ,  Y10S526/931

    Abstract: There are disclosed normally tacky, pressure-sensitive adhesive compositions comprising one or more normally tacky polymers having a T.sub.g of about 0.degree. C. or less and containing pendant functional groups attached to the backbone and having the formula: ##STR1## in which R.sub.1 is a divalent organic radical at least 3 atoms in length, and X is organoacyl or cyano, the polymers preferably also being normally tacky when cured. Such polymers have markedly improved cohesive strength (shear holding value) with little or no detriment to adhesive tack or adhesion (peel resistance), and these improvements are realized without the necessity of incorporating cross-linking monomers such as N-methylolamides or other cross-linking agents. Pressure-sensitive adhesive, water-based emulsions containing such polymers and pressure-sensitive adhesive articles comprising a substrate having at least a portion of one surface thereof coated with the adhesive compositions are also disclosed. In a preferred embodiment, the adhesive compositions further include a polyacid component for further improving cohesive strength, particularly at acidic pH.

    Abstract translation: 公开了通常具有粘性的压敏粘合剂组合物，其包含一种或多种具有约0℃或更低的Tg的通常具有粘性的聚合物，并且含有连接于骨架上的侧链官能团并具有下式：其中R 1为 长度为至少3个原子的二价有机基团，X是有机酰基或氰基，聚合物优选在固化时通常是发粘的。 这些聚合物显着地提高了粘合强度（剪切保持值），很少或没有损害粘合剂粘着性或粘合性（抗剥离性），并且实现了这些改进，而不需要引入交联单体如N-甲基丙烯酰胺或其它交联剂， 连接剂。 还公开了压敏粘合剂，含有这种聚合物的水性乳液和压敏粘合剂制品，其包含具有涂覆有粘合剂组合物的至少一部分表面的基材。 在优选的实施方案中，粘合剂组合物还包括用于进一步提高内聚强度的多酸组分，特别是在酸性pH下。

Patent Agency Ranking