公开(公告)号：US20060161098A1

公开(公告)日：2006-07-20

申请号：US11040524

申请日：2005-01-20

申请人： Henry Nita ,  Jeff Sarge

发明人： Henry Nita ,  Jeff Sarge

IPC分类号： A61B17/20

CPC分类号： A61B17/22012 ,  A61B2017/00477 ,  A61B2017/00526 ,  Y10T29/49908

摘要： A vibrational catheter for disrupting obstructions in lumens such as blood vessels includes an elongate flexible catheter body having a proximal end, a distal end and at least one lumen extending longitudinally therethrough, a vibrational transmission member extending longitudinally through the lumen of the catheter body and having a proximal end and a distal end, and a transition connector attached to the proximal end of the vibrational transmission member for coupling the transmission member with a vibrational energy source. The transition connector includes a bore into which the proximal end of the vibrational transmission member extends. The proximal end of the vibrational transmission member is attached within the bore of the transition connector with variable attachment forces such that the transition connector exerts a lowest amount of attachment force on an attached distal-most portion of the vibrational transmission member housed within the bore.

摘要翻译： 用于破坏血管内腔障碍物的振动导管包括细长的柔性导管主体，其具有近端，远端和纵向穿过其中延伸的至少一个内腔;振动传递构件，纵向延伸穿过导管主体的内腔，并具有 近端和远端，以及连接到振动传递构件的近端的过渡连接器，用于将传动构件与振动能源联接。 过渡连接器包括孔，振动传递构件的近端延伸穿过该孔。 振动传递构件的近端以可变的附接力附接在过渡连接器的孔内，使得过渡连接器在容纳在孔内的振动传动构件的附接的最远部分上施加最低的附着力。

公开(公告)号：US20120232434A1

公开(公告)日：2012-09-13

申请号：US13441825

申请日：2012-04-06

申请人： Henry Nita ,  Jeff Sarge ,  Simon Nguyen

发明人： Henry Nita ,  Jeff Sarge ,  Simon Nguyen

IPC分类号： A61N7/00

CPC分类号： A61B17/22012 ,  A61B2017/00141 ,  A61B2017/00154 ,  A61B2017/00292 ,  A61B2017/003 ,  A61B2017/00331 ,  A61B2017/00526 ,  A61B2017/22011 ,  A61B2017/22014 ,  A61B2017/22015 ,  A61B2017/320072 ,  A61M25/0009 ,  A61M25/001 ,  A61M25/0041

摘要： Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, ultrasound catheters include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and, in some embodiments, a guidewire tube extending through the lumen. A distal head for disrupting occlusions is coupled with the distal end of the ultrasound transmission member and is positioned adjacent the distal end of the catheter body. Some embodiments include improved features such as a bend in the catheter body for enhancing positioning and/or advancement of the catheter.

摘要翻译： 超声导管装置和方法提供增强的血管阻塞的破坏。 通常，超声导管包括具有一个或多个腔的细长柔性导管主体，纵向延伸通过导管体腔的超声波传播构件，并且在一些实施例中，延伸穿过内腔的导丝管。 用于破坏闭塞的远侧头部与超声波传播构件的远端联接并且被定位成邻近导管主体的远端。 一些实施例包括改进的特征，例如导管主体中的弯曲部，用于增强导管的定位和/或前进。

公开(公告)号：US20110237983A1

公开(公告)日：2011-09-29

申请号：US13153359

申请日：2011-06-03

申请人： Henry Nita ,  Jeff Sarge ,  Martinos Tran ,  Simon Nguyen

发明人： Henry Nita ,  Jeff Sarge ,  Martinos Tran ,  Simon Nguyen

IPC分类号： A61N7/00

CPC分类号： A61B17/22 ,  A61B17/22012 ,  A61B2017/00477 ,  A61B2017/22015 ,  A61B2017/22018 ,  A61B2017/22038 ,  A61B2017/320072 ,  A61B2017/320084 ,  A61M37/0092

摘要： Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, an ultrasound catheter includes an elongate flexible catheter body with one or more lumens. An ultrasound transmission member or wire extends longitudinally through the catheter body lumen and, in many embodiments, a guide wire tube also extends through the same lumen. A distal head is fixed to or otherwise mechanically coupled with the distal end of the ultrasound transmission member or wire and is positioned adjacent the distal end of the catheter body. Although the distal end of the catheter body overlaps the distal head, the distal head is not directly affixed to the distal end of the catheter body. Thus, the distal tip may move freely, relative to the distal end of the catheter body when ultrasonic energy is applied through the ultrasound transmission member. Such a freely floating distal head enhances the efficiency of an ultrasound catheter, enabling the catheter to ablate calcific occlusions and increasing the useful life of the ultrasound transmission member and catheter.

摘要翻译： 超声导管装置和方法提供增强的血管阻塞的破坏。 通常，超声导管包括具有一个或多个管腔的细长柔性导管主体。 超声波传输构件或导线纵向延伸通过导管体腔，并且在许多实施例中，导丝管也延伸穿过相同的内腔。 远端头部固定到超声波传播构件或线的远端或以其它方式机械联接，并且邻近导管主体的远端定位。 虽然导管主体的远端与远端头部重叠，但是远侧头部不直接固定到导管主体的远端。 因此，当通过超声波传播构件施加超声波能量时，远端可相对于导管体的远端自由移动。 这种自由浮动的远端头部提高了超声导管的效率，使得导管能够消融钙化闭塞并增加超声波传输部件和导管的使用寿命。

公开(公告)号：US07955293B2

公开(公告)日：2011-06-07

申请号：US11466738

申请日：2006-08-23

申请人： Henry Nita ,  Jeff Sarge ,  Martinos Tran ,  Simon Nguyen

发明人： Henry Nita ,  Jeff Sarge ,  Martinos Tran ,  Simon Nguyen

IPC分类号： A61B17/20

CPC分类号： A61B17/22 ,  A61B17/22012 ,  A61B2017/00477 ,  A61B2017/22015 ,  A61B2017/22018 ,  A61B2017/22038 ,  A61B2017/320072 ,  A61B2017/320084 ,  A61M37/0092

摘要： Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, an ultrasound catheter includes an elongate flexible catheter body with one or more lumens. An ultrasound transmission member or wire extends longitudinally through the catheter body lumen and, in many embodiments, a guide wire tube also extends through the same lumen. A distal head is fixed to or otherwise mechanically coupled with the distal end of the ultrasound transmission member or wire and is positioned adjacent the distal end of the catheter body. Although the distal end of the catheter body overlaps the distal head, the distal head is not directly affixed to the distal end of the catheter body. Thus, the distal tip may move freely, relative to the distal end of the catheter body when ultrasonic energy is applied through the ultrasound transmission member. Such a freely floating distal head enhances the efficiency of an ultrasound catheter, enabling the catheter to ablate calcific occlusions and increasing the useful life of the ultrasound transmission member and catheter.

摘要翻译： 超声导管装置和方法提供增强的血管阻塞的破坏。 通常，超声导管包括具有一个或多个管腔的细长柔性导管主体。 超声波传输构件或导线纵向延伸通过导管体腔，并且在许多实施例中，导丝管也延伸穿过相同的内腔。 远端头部固定到超声波传播构件或线的远端或以其它方式机械联接，并且邻近导管主体的远端定位。 虽然导管主体的远端与远端头部重叠，但是远侧头部不直接固定到导管主体的远端。 因此，当通过超声波传播构件施加超声波能量时，远端可相对于导管体的远端自由移动。 这种自由浮动的远端头部提高了超声导管的效率，使得导管能够消融钙化闭塞并增加超声波传输部件和导管的使用寿命。

公开(公告)号：US07621902B2

公开(公告)日：2009-11-24

申请号：US11466835

申请日：2006-08-24

申请人： Henry Nita ,  Jeff Sarge ,  Martinos Tran ,  Simon Nguyen

发明人： Henry Nita ,  Jeff Sarge ,  Martinos Tran ,  Simon Nguyen

IPC分类号： A61M31/00

CPC分类号： A61B17/22 ,  A61B17/22012 ,  A61B2017/00477 ,  A61B2017/22015 ,  A61B2017/22018 ,  A61B2017/22038 ,  A61B2017/320072 ,  A61B2017/320084 ,  A61M37/0092

摘要： Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, an ultrasound catheter includes an elongate flexible catheter body with one or more lumens. An ultrasound transmission member or wire extends longitudinally through the catheter body lumen and, in many embodiments, a guide wire tube also extends through the same lumen. A distal head is fixed to or otherwise mechanically coupled with the distal end of the ultrasound transmission member or wire and is positioned adjacent the distal end of the catheter body. Although the distal end of the catheter body overlaps the distal head, the distal head is not directly affixed to the distal end of the catheter body. Thus, the distal tip may move freely, relative to the distal end of the catheter body when ultrasonic energy is applied through the ultrasound transmission member. Such a freely floating distal head enhances the efficiency of an ultrasound catheter, enabling the catheter to ablate calcific occlusions and increasing the useful life of the ultrasound transmission member and catheter.

摘要翻译： 超声导管装置和方法提供增强的血管阻塞的破坏。 通常，超声导管包括具有一个或多个管腔的细长柔性导管主体。 超声波传输构件或导线纵向延伸通过导管体腔，并且在许多实施例中，导丝管也延伸穿过相同的内腔。 远端头部固定到超声波传播构件或线的远端或以其它方式机械联接，并且邻近导管主体的远端定位。 虽然导管主体的远端与远端头部重叠，但是远侧头部不直接固定到导管主体的远端。 因此，当通过超声波传播构件施加超声波能量时，远端可相对于导管体的远端自由移动。 这种自由浮动的远端头部提高了超声导管的效率，使得导管能够消融钙化闭塞并增加超声波传输部件和导管的使用寿命。

公开(公告)号：US07137963B2

公开(公告)日：2006-11-21

申请号：US10229371

申请日：2002-08-26

申请人： Henry Nita ,  Jeff Sarge ,  Martinos Tran ,  Simon Nguyen

发明人： Henry Nita ,  Jeff Sarge ,  Martinos Tran ,  Simon Nguyen

IPC分类号： A61B17/20

CPC分类号： A61B17/22 ,  A61B17/22012 ,  A61B2017/00477 ,  A61B2017/22015 ,  A61B2017/22018 ,  A61B2017/22038 ,  A61B2017/320072 ,  A61B2017/320084 ,  A61M37/0092

摘要： Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, an ultrasound catheter includes an elongate flexible catheter body with one or more lumens. An ultrasound transmission member or wire extends longitudinally through the catheter body lumen and, in many embodiments, a guide wire tube also extends through the same lumen. A distal head is fixed to or otherwise mechanically coupled with the distal end of the ultrasound transmission member or wire and is positioned adjacent the distal end of the catheter body. Although the distal end of the catheter body overlaps the distal head, the distal head is not directly affixed to the distal end of the catheter body. Thus, the distal tip may move freely, relative to the distal end of the catheter body when ultrasonic energy is applied through the ultrasound transmission member. Such a freely floating distal head enhances the efficiency of an ultrasound catheter, enabling the catheter to ablate calcific occlusions and increasing the useful life of the ultrasound transmission member and catheter.

公开(公告)号：US20050245951A1

公开(公告)日：2005-11-03

申请号：US11179829

申请日：2005-07-11

申请人： Henry Nita ,  Jeff Sarge ,  Simon Nguyen

发明人： Henry Nita ,  Jeff Sarge ,  Simon Nguyen

IPC分类号： A61B17/22 ,  A61B17/32

CPC分类号： A61B17/22012 ,  A61B2017/00477 ,  A61B2017/22015

摘要： Ultrasound catheter devices and methods of the present invention generally provide for ablation and/or disruption of vascular occlusions. An ultrasound transmission member, such as a wire, transmits vibrational energy from an ultrasound transducer to a distal head of the catheter to disrupt vascular occlusions. At least one absorber member is disposed on or around the ultrasound transmission wire at a location adjacent the sonic connector of the catheter. The absorber member absorbs heat, vibrations, and/or the like from the ultrasound transmission wire at or near the area where the transmission wire is coupled with the sonic connector. The absorptive function typically slows the process of wear and tear on the transmission wire, thus extending the useful life of the ultrasound catheter.

摘要翻译： 本发明的超声导管装置和方法通常提供血管闭塞的消融和/或破坏。 诸如线的超声波传递构件将振动能量从超声换能器传递到导管的远端头部以破坏血管闭塞。 在与导管的声音连接器相邻的位置处，在超声波传输线上或周围设置至少一个吸收体构件。 吸收器构件从传声线与声音连接器耦合的区域处或附近从超声波传输线吸收热量，振动和/或类似物。 吸收功能通常减慢传输线上的磨损和撕裂过程，从而延长超声波导管的使用寿命。

公开(公告)号：US08613751B2

公开(公告)日：2013-12-24

申请号：US12021082

申请日：2008-01-28

申请人： Henry Nita ,  Jeff Sarge

发明人： Henry Nita ,  Jeff Sarge

IPC分类号： A61B17/32 ,  A61B17/20 ,  A61B8/00 ,  A61B8/14 ,  A61M25/00

CPC分类号： A61B17/3207 ,  A61B17/22004 ,  A61B17/2202 ,  A61B17/320068 ,  A61B2017/00243 ,  A61B2017/22014 ,  A61B2017/308 ,  A61M25/0054

摘要： Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Ultrasound catheter devices generally include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and a distal head coupled with the transmission member and positioned adjacent the distal end of the catheter body for disrupting occlusions. Improved features of ultrasound catheters include catheter bodies and ultrasound transmission members with increasing distal flexibility, guidewire tubes allowing contact between a guidewire and an ultrasound transmission member, distal heads with improved guidewire lumens, and torquable proximal housings for enhancing disruption of blood vessel occlusions.

摘要翻译： 超声导管装置和方法提供增强的血管阻塞的破坏。 超声导管装置通常包括具有一个或多个管腔的细长柔性导管主体，纵向延伸穿过导管体腔的超声波传播构件和与传播构件联接并远离导管主体的远端定位以阻止闭塞的远端头部。 超声导管的改进的特征包括具有越来越远的柔性的导管体和超声传递构件，允许导丝和超声波传递构件之间接触的导丝管，具有改进的导丝腔的远端头部以及用于增强血管闭塞的破坏的扭转近端壳体。

公开(公告)号：US20120232435A1

公开(公告)日：2012-09-13

申请号：US13441828

申请日：2012-04-06

申请人： Henry Nita ,  Jeff Sarge ,  Simon Nguyen

发明人： Henry Nita ,  Jeff Sarge ,  Simon Nguyen

IPC分类号： A61N7/00

CPC分类号： A61B17/22012 ,  A61B2017/00141 ,  A61B2017/00154 ,  A61B2017/00292 ,  A61B2017/003 ,  A61B2017/00331 ,  A61B2017/00526 ,  A61B2017/22011 ,  A61B2017/22014 ,  A61B2017/22015 ,  A61B2017/320072 ,  A61M25/0009 ,  A61M25/001 ,  A61M25/0041

摘要： Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, ultrasound catheters include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and, in some embodiments, a guidewire tube extending through the lumen. A distal head for disrupting occlusions is coupled with the distal end of the ultrasound transmission member and is positioned adjacent the distal end of the catheter body. Some embodiments include improved features such as a bend in the catheter body for enhancing positioning and/or advancement of the catheter.

公开(公告)号：US08221343B2

公开(公告)日：2012-07-17

申请号：US11040524

申请日：2005-01-20

申请人： Henry Nita ,  Jeff Sarge

发明人： Henry Nita ,  Jeff Sarge

IPC分类号： A61B17/20

CPC分类号： A61B17/22012 ,  A61B2017/00477 ,  A61B2017/00526 ,  Y10T29/49908

摘要： A vibrational catheter for disrupting obstructions in lumens such as blood vessels includes an elongate flexible catheter body having a proximal end, a distal end and at least one lumen extending longitudinally therethrough, a vibrational transmission member extending longitudinally through the lumen of the catheter body and having a proximal end and a distal end, and a transition connector attached to the proximal end of the vibrational transmission member for coupling the transmission member with a vibrational energy source. The transition connector includes a bore into which the proximal end of the vibrational transmission member extends. The proximal end of the vibrational transmission member is attached within the bore of the transition connector with variable attachment forces such that the transition connector exerts a lowest amount of attachment force on an attached distal-most portion of the vibrational transmission member housed within the bore.

摘要翻译： 用于破坏血管内腔障碍物的振动导管包括细长的柔性导管主体，其具有近端，远端和纵向穿过其中延伸的至少一个内腔;振动传递构件，纵向延伸通过导管主体的内腔，并具有 近端和远端，以及连接到振动传递构件的近端的过渡连接器，用于将传动构件与振动能源联接。 过渡连接器包括孔，振动传递构件的近端延伸穿过该孔。 振动传递构件的近端以可变的附接力附接在过渡连接器的孔内，使得过渡连接器在容纳在孔内的振动传动构件的附接的最远部分上施加最低的附着力。