公开(公告)号：US08668709B2

公开(公告)日：2014-03-11

申请号：US12036870

申请日：2008-02-25

申请人： Henry Nita ,  Jeff Sarge

发明人： Henry Nita ,  Jeff Sarge

IPC分类号： A61B17/32 ,  A61B5/00

CPC分类号： A61B17/3207 ,  A61B17/22004 ,  A61B17/2202 ,  A61B17/320068 ,  A61B2017/00243 ,  A61B2017/22014 ,  A61B2017/308 ,  A61M25/0054

摘要： Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Ultrasound catheter devices generally include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and a distal head coupled with the transmission member and positioned adjacent the distal end of the catheter body for disrupting occlusions. Improved features of ultrasound catheters include catheter bodies and ultrasound transmission members with increasing distal flexibility, guidewire tubes allowing contact between a guidewire and an ultrasound transmission member, distal heads with improved guidewire lumens, and torquable proximal housings for enhancing disruption of blood vessel occlusions.

摘要翻译： 超声导管装置和方法提供增强的血管阻塞的破坏。 超声导管装置通常包括具有一个或多个管腔的细长柔性导管主体，纵向延伸穿过导管体腔的超声波传播构件和与传播构件联接并远离导管主体的远端定位以阻止闭塞的远端头部。 超声导管的改进的特征包括具有越来越远的柔性的导管体和超声传递构件，允许导丝和超声波传递构件之间接触的导丝管，具有改进的导丝腔的远端头部以及用于增强血管闭塞的破坏的扭转近端壳体。

公开(公告)号：US20120238946A1

公开(公告)日：2012-09-20

申请号：US13441829

申请日：2012-04-06

申请人： Henry Nita ,  Jeff Sarge ,  Simon Nguyen

发明人： Henry Nita ,  Jeff Sarge ,  Simon Nguyen

IPC分类号： A61M37/00

CPC分类号： A61B17/22012 ,  A61B2017/00141 ,  A61B2017/00154 ,  A61B2017/00292 ,  A61B2017/003 ,  A61B2017/00331 ,  A61B2017/00526 ,  A61B2017/22011 ,  A61B2017/22014 ,  A61B2017/22015 ,  A61B2017/320072 ,  A61M25/0009 ,  A61M25/001 ,  A61M25/0041

摘要： Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, ultrasound catheters include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and, in some embodiments, a guidewire tube extending through the lumen. A distal head for disrupting occlusions is coupled with the distal end of the ultrasound transmission member and is positioned adjacent the distal end of the catheter body. Some embodiments include improved features such as a bend in the catheter body for enhancing positioning and/or advancement of the catheter.

公开(公告)号：US20120016272A1

公开(公告)日：2012-01-19

申请号：US13243648

申请日：2011-09-23

申请人： Henry Nita ,  Jeff Sarge ,  Simon Nguyen ,  Richard Spano

发明人： Henry Nita ,  Jeff Sarge ,  Simon Nguyen ,  Richard Spano

IPC分类号： A61N7/00

CPC分类号： A61B17/22012 ,  A61B2017/00292 ,  A61B2017/0046 ,  A61B2017/00477 ,  A61B2017/22014 ,  A61B2017/22015 ,  A61B2017/22039 ,  A61B2017/22065 ,  A61B2017/320084 ,  A61B2017/320088 ,  Y10S29/019

摘要： Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, ultrasound catheters include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and a distal head coupled with the transmission member and positioned adjacent the distal end of the catheter body for disrupting occlusions. Improved features of ultrasound catheters include prevention of independent rotation of the ultrasound transmission member, a safety anchor for the distal head, a one-piece transmission member/distal head and the like.

摘要翻译： 超声导管装置和方法提供增强的血管阻塞的破坏。 通常，超声导管包括具有一个或多个腔的细长柔性导管体，纵向延伸穿过导管体腔的超声波传播构件和与传播构件联接并远离导管主体的远端定位以阻止闭塞的远端头。 超声波导管的改进特征包括防止超声波传输构件的独立旋转，用于远端头部的安全锚，单件传动构件/远端头等。

公开(公告)号：US20090216246A1

公开(公告)日：2009-08-27

申请号：US12428183

申请日：2009-04-22

申请人： Henry Nita ,  Jeff Sarge ,  Richard Spano

发明人： Henry Nita ,  Jeff Sarge ,  Richard Spano

IPC分类号： A61B17/22

CPC分类号： A61B17/22004 ,  A61B17/22012 ,  A61B17/2251 ,  A61B2017/00477 ,  A61B2017/22014

摘要： Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, an ultrasound catheter device includes an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and a distal head coupled with the transmission member and positioned adjacent the distal end of the catheter body for disrupting occlusions. A proximal housing of the catheter device may include one or more features for dissipating heat from the ultrasound transmission wire, such as a fluid inlet aperture for passage of fluid, use of heat conductive materials in the proximal housing, surface features to increase the housing's surface area, heat conductive members disposed adjacent the transmission member and the like. Various irrigation fluids may be used, such as cooled, oxygen supersaturated or lubricious fluids.

摘要翻译： 超声导管装置和方法提供增强的血管阻塞的破坏。 通常，超声导管装置包括具有一个或多个腔的细长柔性导管体，纵向延伸穿过导管体腔的超声波传播构件和与传播构件联接并远离导管主体的远端定位的远端头，用于破坏 闭塞。 导管装置的近侧壳体可以包括用于从超声波传输线散发热量的一个或多个特征，例如用于流体通过的流体入口孔，在近侧壳体中使用导热材料，表面特征以增加壳体的表面 区域，布置在传输构件附近的导热构件等。 可以使用各种冲洗流体，例如冷却的，氧过饱和的或润滑的流体。

公开(公告)号：US20080167602A1

公开(公告)日：2008-07-10

申请号：US12021082

申请日：2008-01-28

申请人： Henry Nita ,  Jeff Sarge

发明人： Henry Nita ,  Jeff Sarge

IPC分类号： A61N7/02

CPC分类号： A61B17/3207 ,  A61B17/22004 ,  A61B17/2202 ,  A61B17/320068 ,  A61B2017/00243 ,  A61B2017/22014 ,  A61B2017/308 ,  A61M25/0054

摘要： Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Ultrasound catheter devices generally include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and a distal head coupled with the transmission member and positioned adjacent the distal end of the catheter body for disrupting occlusions. Improved features of ultrasound catheters include catheter bodies and ultrasound transmission members with increasing distal flexibility, guidewire tubes allowing contact between a guidewire and an ultrasound transmission member, distal heads with improved guidewire lumens, and torquable proximal housings for enhancing disruption of blood vessel occlusions.

公开(公告)号：US20070021691A1

公开(公告)日：2007-01-25

申请号：US11466835

申请日：2006-08-24

申请人： Henry Nita ,  Jeff Sarge ,  Martinos Tran ,  Simon Nguyen

发明人： Henry Nita ,  Jeff Sarge ,  Martinos Tran ,  Simon Nguyen

IPC分类号： A61H1/00

CPC分类号： A61B17/22 ,  A61B17/22012 ,  A61B2017/00477 ,  A61B2017/22015 ,  A61B2017/22018 ,  A61B2017/22038 ,  A61B2017/320072 ,  A61B2017/320084 ,  A61M37/0092

摘要： Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, an ultrasound catheter includes an elongate flexible catheter body with one or more lumens. An ultrasound transmission member or wire extends longitudinally through the catheter body lumen and, in many embodiments, a guide wire tube also extends through the same lumen. A distal head is fixed to or otherwise mechanically coupled with the distal end of the ultrasound transmission member or wire and is positioned adjacent the distal end of the catheter body. Although the distal end of the catheter body overlaps the distal head, the distal head is not directly affixed to the distal end of the catheter body. Thus, the distal tip may move freely, relative to the distal end of the catheter body when ultrasonic energy is applied through the ultrasound transmission member. Such a freely floating distal head enhances the efficiency of an ultrasound catheter, enabling the catheter to ablate calcific occlusions and increasing the useful life of the ultrasound transmission member and catheter.

公开(公告)号：US10285719B2

公开(公告)日：2019-05-14

申请号：US13526358

申请日：2012-06-18

申请人： Henry Nita ,  Jeff Sarge

发明人： Henry Nita ,  Jeff Sarge

IPC分类号： A61B17/22 ,  A61B17/00

摘要： A vibrational catheter for disrupting obstructions in lumens such as blood vessels includes an elongate flexible catheter body having a proximal end, a distal end and at least one lumen extending longitudinally therethrough, a vibrational transmission member extending longitudinally through the lumen of the catheter body and having a proximal end and a distal end, and a transition connector attached to the proximal end of the vibrational transmission member for coupling the transmission member with a vibrational energy source. The transition connector includes a bore into which the proximal end of the vibrational transmission member extends. The proximal end of the vibrational transmission member is attached within the bore of the transition connector with variable attachment forces such that the transition connector exerts a lowest amount of attachment force on an attached distal-most portion of the vibrational transmission member housed within the bore.

公开(公告)号：US08961423B2

公开(公告)日：2015-02-24

申请号：US12572118

申请日：2009-10-01

申请人： Henry Nita ,  Jeff Sarge ,  Simon Nguyen

发明人： Henry Nita ,  Jeff Sarge ,  Simon Nguyen

IPC分类号： A61B8/14 ,  A61B17/22 ,  A61B17/00

CPC分类号： A61B17/22012 ,  A61B2017/00477 ,  A61B2017/22015

摘要： Ultrasound catheter devices and methods of the present invention generally provide for ablation and/or disruption of vascular occlusions. An ultrasound transmission member, such as a wire, transmits vibrational energy from an ultrasound transducer to a distal head of the catheter to disrupt vascular occlusions. An absorber member is disposed on or around the ultrasound transmission wire at a location adjacent the sonic connector of the catheter. The absorber member absorbs heat, vibrations, and/or the like from the ultrasound transmission wire at or near the area where the transmission wire is coupled with the sonic connector. The absorptive function typically slows the process of wear and tear on the transmission wire, thus extending the useful life of the ultrasound catheter.

摘要翻译： 本发明的超声导管装置和方法通常提供血管闭塞的消融和/或破坏。 诸如线的超声波传递构件将振动能量从超声换能器传递到导管的远端头部以破坏血管闭塞。 吸收器构件设置在超声波传输线上或周围的与导管的声音连接器相邻的位置处。 吸收器构件从传声线与声音连接器耦合的区域处或附近从超声波传输线吸收热量，振动和/或类似物。 吸收功能通常减慢传输线上的磨损和撕裂过程，从而延长超声波导管的使用寿命。

公开(公告)号：US20150039004A1

公开(公告)日：2015-02-05

申请号：US14365016

申请日：2012-01-18

申请人： Jeff Sarge

发明人： Jeff Sarge

IPC分类号： A61B17/32 ,  A61M29/00

CPC分类号： A61B17/2202 ,  A61B17/22012 ,  A61B17/320068 ,  A61B50/13 ,  A61B2017/003 ,  A61B2017/00778 ,  A61B2017/22014 ,  A61B2017/22095 ,  A61B2017/320056 ,  A61F2/958 ,  A61F2250/0093 ,  A61M29/00

摘要： An ultrasonic device having a tri-axial configuration including an ultrasound transmission member, a dilator, and a sheath is disclosed. The ultrasound device may be used in a procedure to treat an occluded blood vessel. The ultrasound transmission member can transmit ultrasonic energy from an ultrasonic transducer to a distal end. The dilator facilitates entry of the ultrasonic transmission member into the subintimal space of a blood vessel. The sheath may articulate to aid in the process of re-entering the central lumen of the blood vessel.

摘要翻译： 公开了一种具有包括超声波传递部件，扩张器和护套的三轴构型的超声波装置。 超声波装置可以用于治疗闭塞血管的过程。 超声波传递部件能够将超声波能量从超声波传感器发送到远端。 扩张器便于超声波传播部件进入血管的内膜下空间。 护套可以铰接以帮助重新进入血管的中心腔的过程。

公开(公告)号：US20120311844A1

公开(公告)日：2012-12-13

申请号：US13526358

申请日：2012-06-18

申请人： Henry Nita ,  Jeff Sarge

发明人： Henry Nita ,  Jeff Sarge

IPC分类号： A61B17/22

CPC分类号： A61B17/22012 ,  A61B2017/00477 ,  A61B2017/00526 ,  Y10T29/49908

摘要： A vibrational catheter for disrupting obstructions in lumens such as blood vessels includes an elongate flexible catheter body having a proximal end, a distal end and at least one lumen extending longitudinally therethrough, a vibrational transmission member extending longitudinally through the lumen of the catheter body and having a proximal end and a distal end, and a transition connector attached to the proximal end of the vibrational transmission member for coupling the transmission member with a vibrational energy source. The transition connector includes a bore into which the proximal end of the vibrational transmission member extends. The proximal end of the vibrational transmission member is attached within the bore of the transition connector with variable attachment forces such that the transition connector exerts a lowest amount of attachment force on an attached distal-most portion of the vibrational transmission member housed within the bore.

摘要翻译： 用于破坏血管内腔障碍物的振动导管包括细长的柔性导管主体，其具有近端，远端和纵向穿过其中延伸的至少一个内腔;振动传递构件，纵向延伸穿过导管主体的内腔，并具有 近端和远端，以及连接到振动传递构件的近端的过渡连接器，用于将传动构件与振动能源联接。 过渡连接器包括孔，振动传递构件的近端延伸穿过该孔。 振动传递构件的近端以可变的附接力附接在过渡连接器的孔内，使得过渡连接器在容纳在孔内的振动传动构件的附接的最远部分上施加最低的附着力。