Monoclonal antibodies for N-peptide
    31.
    发明授权
    Monoclonal antibodies for N-peptide 失效
    N-肽单克隆抗体

    公开(公告)号:US5859203A

    公开(公告)日:1999-01-12

    申请号:US907747

    申请日:1997-08-08

    摘要: The present invention relates to a sandwich immunoassay for rapidly and readily measuring N-peptide using two kinds of monoclonal antibodies recognizing different portions of the N-peptide. The method for measuring N-peptide or a precursor thereof includes the steps of: incubating a mixture containing a sample and a first monoclonal antibody recognizing a portion of N-peptide; adding a labelled second monoclonal antibody recognizing a portion of N-peptide to the mixture, followed by further incubation; and detecting the resulting antigen-antibody complex in the mixture. Alternatively, the method includes the steps of: incubating a mixture containing a sample, a first monoclonal antibody recognizing a portion of N-peptide, and a labelled second monoclonal antibody recognizing another portion of N-peptide; and detecting the resulting antigen-antibody complex.

    摘要翻译: 本发明涉及使用识别N-肽的不同部分的两种单克隆抗体快速且容易地测量N-肽的夹心免疫测定。 用于测量N-肽或其前体的方法包括以下步骤:将含有样品和识别N肽部分的第一单克隆抗体的混合物孵育; 将识别一部分N-肽的标记的第二单克隆抗体加入到混合物中,随后进一步培养; 并检测混合物中得到的抗原 - 抗体复合物。 或者,该方法包括以下步骤:将含有样品的混合物,识别N肽部分的第一单克隆抗体和识别N-肽的另一部分的标记的第二单克隆抗体孵育; 并检测所得到的抗原 - 抗体复合物。

    Hybridoma producing a monoclonal antibody for N-peptide
    32.
    发明授权
    Hybridoma producing a monoclonal antibody for N-peptide 失效
    产生N-肽单克隆抗体的杂交瘤

    公开(公告)号:US5827674A

    公开(公告)日:1998-10-27

    申请号:US909002

    申请日:1997-08-08

    摘要: The present invention relates to a sandwich immunoassay for rapidly and readily measuring N-peptide using two kinds of monoclonal antibodies recognizing different portions of the N-peptide. The method for measuring N-peptide or a precursor thereof includes the steps of: incubating a mixture containing a sample and a first monoclonal antibody recognizing a portion of N-peptide; adding a labelled second monoclonal antibody recognizing a portion of N-peptide to the mixture, followed by further incubation; and detecting the resulting antigen-antibody complex in the mixture. Alternatively, the method includes the steps of: incubating a mixture containing a sample, a first monoclonal antibody recognizing a portion of N-peptide, and a labelled second monoclonal antibody recognizing another portion of N-peptide; and detecting the resulting antigen-antibody complex.

    摘要翻译: 本发明涉及使用识别N-肽的不同部分的两种单克隆抗体快速且容易地测量N-肽的夹心免疫测定。 用于测量N-肽或其前体的方法包括以下步骤:将含有样品和识别N肽部分的第一单克隆抗体的混合物孵育; 将识别一部分N-肽的标记的第二单克隆抗体加入到混合物中,随后进一步培养; 并检测混合物中得到的抗原 - 抗体复合物。 或者,该方法包括以下步骤:将含有样品的混合物,识别N肽部分的第一单克隆抗体和识别N-肽的另一部分的标记的第二单克隆抗体孵育; 并检测所得到的抗原 - 抗体复合物。

    Mold for molding optical element
    33.
    发明授权
    Mold for molding optical element 失效
    用于模制光学元件的模具

    公开(公告)号:US5711780A

    公开(公告)日:1998-01-27

    申请号:US453354

    申请日:1995-05-30

    申请人: Yasushi Taniguchi

    发明人: Yasushi Taniguchi

    摘要: A mold for press molding an optical element of glass has carbon atoms injected in amounts from 10.sup.15 to 10.sup.18 ion/cm.sup.2 into a molding surface of a mold base of the mold and subjected to further treatment to form on the molding surface a diamond film, a hydrogenated amorphous carbon film, a hard carbon film or a mixture of at least two such films. The film on the molding surface can be formed by heat treatment and, additionally, by irradiation with hydrogen plasma, after carbon ion injection.

    摘要翻译: 用于将玻璃的光学元件压制成型的模具将碳原子以1015至1018离子/ cm 2的量注入到模具的模具底座的模制表面中,并进一步处理以在模制表面上形成金刚石膜, 氢化无定形碳膜,硬碳膜或至少两种这样的膜的混合物。 成型面上的膜可以通过热处理形成,另外通过在碳离子注入后用氢等离子体照射来形成。

    Mold with hydrogenated amorphous carbon film for molding an optical
element
    36.
    发明授权
    Mold with hydrogenated amorphous carbon film for molding an optical element 失效
    具有用于模制光学元件的氢化非晶碳膜的模具

    公开(公告)号:US5026415A

    公开(公告)日:1991-06-25

    申请号:US394208

    申请日:1989-08-15

    IPC分类号: C03B11/08 C04B41/85

    摘要: This specification discloses a mold for use for press-molding an optical element, characterized in that at least the molding surface of a mold base material is coated with an a-C:H film containing 5-40 atom % of hydrogen therein and having a film density of 1.5 g/cm.sup.3 or more. Other mold coating films also disclosed are a hydrogenated amorphous carbon film with an intermediate carbide layer between the film and the molding surface, and a hard carbon film containing 0-5 atom % of hydrogen therein and having a spin density of 1.times.10.sup.18 spin/cm.sup.3 or less and a film densisy of 1.5 g/cm.sup.3 or more.

    摘要翻译: 本说明书公开了一种用于对光学元件进行加压成型的模具,其特征在于,至少模具基材的成型表面涂覆有含有5-40原子%的氢的aC:H膜,并具有膜密度 为1.5g / cm 3以上。 还公开了其他模具涂膜是在膜和成型表面之间具有中间碳化物层的氢化无定形碳膜,以及其中含有0-5原子%氢的硬质碳膜,其自旋密度为1×10 18 spin / cm 3或 更小,膜密度为1.5g / cm 3以上。