Protein kinase inhibitors
    34.
    发明授权
    Protein kinase inhibitors 有权
    蛋白激酶抑制剂

    公开(公告)号:US07705004B2

    公开(公告)日:2010-04-27

    申请号:US12192034

    申请日:2008-08-14

    IPC分类号: C07D487/04 A61K31/519

    CPC分类号: C07D487/04

    摘要: Compounds, particularly compounds having spleen tyrosine kinase (Syk) inhibition activity, having the following structure: or a pharmaceutically acceptable salt thereof, wherein R1 is structure (a), (b), (c) or (d): and Ra, Rb, Rc, R2, R3, R4, R5, R6 and R7 are as defined herein. Methods associated with preparation and use of the same, as well as pharmaceutical compositions containing the same, are also disclosed, as well as uses of the same to treat a condition or disorder mediated by a Syk and/or JAK kinase.

    摘要翻译: 具有以下结构的化合物,特别是具有脾酪氨酸激酶(Syk)抑制活性的化合物或其药学上可接受的盐,其中R 1是结构(a),(b),(c)或(d):和Ra,Rb ,Rc,R2,R3,R4,R5,R6和R7如本文所定义。 还公开了与其制备和使用相关的方法以及含有该组合物的药物组合物,以及其用于治疗由Syk和/或JAK激酶介导的病症或病症的用途。

    System and Method for Corpus Callosum Segmentation in Magnetic Resonance Images
    35.
    发明申请
    System and Method for Corpus Callosum Segmentation in Magnetic Resonance Images 有权
    磁共振图像中胼los体分割的系统和方法

    公开(公告)号:US20080037848A1

    公开(公告)日:2008-02-14

    申请号:US11782828

    申请日:2007-07-25

    IPC分类号: G06K9/00

    摘要: A method and system for segmentation of the corpus callosum in MR brain images is disclosed. The method utilizes an active shape model (ASM) with confidence weighting to iteratively adjust an initial corpus callosum contour to define a boundary of the corpus callosum in an MR image. An ASM is used to determine a displacement value in a perpendicular direction of the corpus callosum contour for each node of the corpus callosum contour. The displacement value for each node is then weighted based on a confidence of that displacement value. The ASM is then fitted to the adjusted contour. These steps are iteratively performed until the contour converges to define the corpus callosum boundary. This boundary can be further refined based on intensity distributions in object and background regions defined by the boundary.

    摘要翻译: 公开了MR脑图像中胼the体分割的方法和系统。 该方法利用具有置信度加权的活动形状模型(ASM)来迭代地调整初始语料库胼los体轮廓,以定义MR图像中胼the体的边界。 ASM用于确定胼the体轮廓的每个节点的胼um体轮廓的垂直方向上的位移值。 然后基于该位移值的置信度对每个节点的位移值加权。 然后将ASM安装到调整后的轮廓上。 迭代地执行这些步骤,直到轮廓收敛以定义胼the体边界。 该边界可以根据由边界定义的对象和背景区域中的强度分布进一步改进。

    Touch display having a reflective type display screen
    36.
    发明授权
    Touch display having a reflective type display screen 有权
    具有反射型显示屏的触摸显示器

    公开(公告)号:US09310918B2

    公开(公告)日:2016-04-12

    申请号:US13976678

    申请日:2011-12-27

    申请人: Qing Xu Xiangtao Liu

    发明人: Qing Xu Xiangtao Liu

    IPC分类号: G06F3/045 G06F3/041

    CPC分类号: G06F3/0412

    摘要: The present disclosure provides a display module, an electronic device and a control method thereof. The display module may comprise: a covering unit satisfying a first light transmittance, comprising a touch area; a sensing unit satisfying a second light transmittance, comprising a sensing layer, wherein the covering unit is arranged on a first side of the sensing layer, and the sensing layer is configured to sense a touch position of an operator in the touch area when the operator touches the touch area; a reflective type display unit, comprising a display layer and a reflective surface, wherein the display unit is arranged on a second side of the sensing layer, and the display layer and the reflective surface are respectively opposite to the sensing layer. The display unit displays images through the display layer, and a distance between the reflective surface and the sensing unit is larger than or equal to a distance between the display layer and the sensing unit, wherein an incident light arriving at the reflective surface forms a reflected light capable of transmitting through the sensing unit and the covering unit.

    摘要翻译: 本公开提供了一种显示模块,电子设备及其控制方法。 显示模块可以包括:满足第一透光率的覆盖单元,包括触摸区域; 感测单元,其满足第二透光率,包括感测层,其中所述覆盖单元布置在所述感测层的第一侧上,并且所述感测层被配置为当所述操作者在所述触摸区域中感测到所述触摸区域中的操作者的触摸位置 触摸触摸区域; 反射型显示单元,包括显示层和反射表面,其中所述显示单元布置在所述感测层的第二侧上,并且所述显示层和所述反射表面分别与所述感测层相对。 显示单元通过显示层显示图像,并且反射表面和感测单元之间的距离大于或等于显示层和感测单元之间的距离,其中到达反射表面的入射光形成反射的 能够通过感测单元和覆盖单元传输的光。

    Wavelength Based Optical Power Positioning for Information and Communications Technology Systems
    38.
    发明申请
    Wavelength Based Optical Power Positioning for Information and Communications Technology Systems 有权
    用于信息和通信技术系统的基于波长的光功率定位

    公开(公告)号:US20140016934A1

    公开(公告)日:2014-01-16

    申请号:US13545200

    申请日:2012-07-10

    IPC分类号: H04J14/02

    摘要: Wavelength-based optical power provisioning is provided by multiplexing a plurality of continuous wave light beams at different wavelengths onto a single optical fiber as a multiplexed light source and demultiplexing the multiplexed light source based on wavelength at a photonic unit coupled to the optical fiber to recover the continuous wave light beams. The recovered continuous wave light beams are split into a plurality of light beams by the photonic unit, each light beam having the same wavelength and the same or lower power as one of the recovered continuous wave light beams so that at least one of the light beams generated by the photonic unit has a higher power than the other light beams generated by the photonic unit.

    摘要翻译: 基于波长的光功率供给通过将多个不同波长的连续波光束多路复用到作为复用光源的单个光纤上并且基于耦合到光纤的光子单元的波长来解复用多路复用光源来恢复 连续波光束。 回收的连续波束通过光子单元被分成多个光束,每个光束具有与恢复的连续波束光束之一相同的波长和相同或更低的功率,使得至少一个光束 由光子单元生成的光功率比由光子单元产生的其它光束具有更高的功率。

    OXYPYRIMIDINES AS SYK MODULATORS
    39.
    发明申请
    OXYPYRIMIDINES AS SYK MODULATORS 审中-公开
    氧化亚胺作为SYK调节剂

    公开(公告)号:US20130317029A1

    公开(公告)日:2013-11-28

    申请号:US13882958

    申请日:2011-11-01

    摘要: The present invention is directed to compounds of formula (I) and tautomers thereof or pharmaceutically acceptable salts, esters, and prodrugs thereof which arc inhibitor of Syk kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition Syk kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by Syk kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma.

    摘要翻译: 本发明涉及其抑制Syk激酶的式(I)化合物及其互变异构体或其药学上可接受的盐,酯和前药。 本发明还涉及用于制备这些化合物的中间体,这种化合物的制备,含有这种化合物的药物组合物,抑制Syk激酶活性的方法,抑制血小板聚集的方法,以及预防或治疗数字的方法 至少部分地由Syk激酶活性介导的病症,例如不期望的血栓形成和非霍奇金淋巴瘤。

    Ignition control apparatus used in electronic ballast and method thereof
    40.
    发明授权
    Ignition control apparatus used in electronic ballast and method thereof 有权
    电子镇流器中使用的点火控制装置及其方法

    公开(公告)号:US08593080B2

    公开(公告)日:2013-11-26

    申请号:US13088251

    申请日:2011-04-15

    摘要: The present invention is generally related to an electronic ballast, an ignition control apparatus used therein and associated method of operation. In one embodiment, an electronic ballast comprising an inverter and an ignition control apparatus which comprises a stability monitoring circuit and a controlled ignition circuit. The inverter converts a DC input voltage into an AC voltage to drive a gas discharge lamp. The stability monitoring circuit monitors whether the DC input voltage is stable. The controlled ignition circuit is electrically coupled to the stability monitoring circuit and the lamp, ignites the lamp based on the monitoring result. The controlled ignition circuit does not ignite the gas discharge lamp until the DC input voltage becomes stable.

    摘要翻译: 本发明通常涉及电子镇流器,其中使用的点火控制装置和相关的操作方法。 在一个实施例中,一种电子镇流器包括逆变器和点火控制装置,其包括稳定性监视电路和受控点火电路。 逆变器将直流输入电压转换为交流电压以驱动气体放电灯。 稳定监视电路监视直流输入电压是否稳定。 受控点火电路电耦合到稳定性监测电路和灯,基于监测结果点燃灯。 直流输入电压稳定后,控制点火电​​路不会点燃气体放电灯。