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公开(公告)号:US20130245016A1
公开(公告)日:2013-09-19
申请号:US13990505
申请日:2011-11-30
IPC分类号: C07D401/12 , C07D417/14 , C07D401/14
CPC分类号: C07D401/12 , C07D401/14 , C07D417/14
摘要: Herein are disclosed indoles of formula (I) where the various groups are defined herein, and which are useful for treating cancer.
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公开(公告)号:US07759340B2
公开(公告)日:2010-07-20
申请号:US12411600
申请日:2009-03-26
IPC分类号: C07D498/04 , C07D513/04 , A61K31/542 , A61K31/436
CPC分类号: C07D519/00 , C07D471/04 , C07D498/04 , C07D513/04
摘要: Naphthyridine and quinoline derivatives useful in the treatment of bacterial infections in mammals, particularly humans, are disclosed herein.
摘要翻译: 本文公开了可用于治疗哺乳动物,特别是人类细菌感染的萘啶和喹啉衍生物。
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公开(公告)号:US07709496B2
公开(公告)日:2010-05-04
申请号:US12296119
申请日:2007-04-05
IPC分类号: C07D491/04 , C07D498/04 , A61K31/436 , A61K31/542
CPC分类号: C07D491/056 , C07D498/04 , C07D513/04
摘要: 2H-chromen-2-one derivatives useful in the treatment of bacterial infections in mammals, particularly humans, are disclosed herein.
摘要翻译: 本文公开了可用于治疗哺乳动物,特别是人类细菌感染的2H-色烯-2-酮衍生物。
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公开(公告)号:US07655648B2
公开(公告)日:2010-02-02
申请号:US11572929
申请日:2005-08-02
IPC分类号: C07D498/08 , C07D513/04 , A61K31/542 , A61K31/5383
CPC分类号: C07D519/00 , A61K31/397 , C07D513/04 , Y02A50/473
摘要: Naphthalene, quinoline, quinoxaline and naphthyridine derivatives useful in the treatment of bacterial infections in mammals, particularly humans, are disclosed herein.
摘要翻译: 本文公开了可用于治疗哺乳动物,特别是人类细菌感染的萘,喹啉,喹喔啉和萘啶衍生物。
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公开(公告)号:US07592334B2
公开(公告)日:2009-09-22
申请号:US11814614
申请日:2006-01-24
IPC分类号: C07D498/04 , C07D513/04 , A61K31/542 , A61K31/436
CPC分类号: C07D471/04
摘要: Naphthyridine and related derivatives useful in the treatment of bacterial infections, particularly humans, are disclosed herein.
摘要翻译: 本文公开了用于治疗细菌感染,特别是人的萘吡啶和相关衍生物。
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公开(公告)号:US20080194547A1
公开(公告)日:2008-08-14
申请号:US11570443
申请日:2005-07-08
IPC分类号: A61K31/542 , C07D513/04 , A61K31/5383 , A61P31/04 , C07D498/04
CPC分类号: Y02P20/55
摘要: Naphthalene, quinoline, quinoaline and naphthyridine derivatives useful in the treatment of bacterial infections in mammals, particularly humans, are disclosed herein.
摘要翻译: 本文公开了可用于治疗哺乳动物,特别是人类细菌感染的萘,喹啉,喹喔啉和萘啶衍生物。
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公开(公告)号:US06825188B2
公开(公告)日:2004-11-30
申请号:US10691241
申请日:2003-10-22
申请人: James Francis Callahan , Russell Donovan Cousins , Richard McCulloch Keenan , Chet Kwon , William Henry Miller , Irene Nijole Uzinskas
发明人: James Francis Callahan , Russell Donovan Cousins , Richard McCulloch Keenan , Chet Kwon , William Henry Miller , Irene Nijole Uzinskas
IPC分类号: A61K3144
CPC分类号: C07D223/16 , A61K31/55 , A61K33/24 , A61K45/06 , C07D401/12 , C07D403/12 , C07D417/12 , A61K2300/00
摘要: Compounds having a benzodiazepinyl core structure are disclosed which are vitronectin receptor antagonists useful in the treatment of osteoporosis, angiogenesis, tumor growth and metastasis, atherosclerosis, restenosis and inflammation.
摘要翻译: 公开了具有苯并二氮杂环核心结构的化合物,其是可用于治疗骨质疏松症,血管生成,肿瘤生长和转移,动脉粥样硬化,再狭窄和炎症的玻连蛋白受体拮抗剂。
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38.
公开(公告)号:US06060462A
公开(公告)日:2000-05-09
申请号:US904881
申请日:1997-08-01
申请人: Robert Anthony Galemmo, Jr. , Matthew Mark Abelman , Eugene Cruz Amparo , John Matthew Fevig , Robert Madara Knabb , William Henry Miller , Gregory James Pacofsky , Patricia Carol Weber , Joseph Cacciola
发明人: Robert Anthony Galemmo, Jr. , Matthew Mark Abelman , Eugene Cruz Amparo , John Matthew Fevig , Robert Madara Knabb , William Henry Miller , Gregory James Pacofsky , Patricia Carol Weber , Joseph Cacciola
CPC分类号: C07K7/02 , C07F5/025 , C07F9/5325 , C07K5/06191 , A61K38/00
摘要: This invention relates to electrophilic dipeptide analogs conjugated to an N,N-disubstituted .alpha.-amino acid as inhibitors of trypsin-like serine protease enzymes.
摘要翻译: 本发明涉及与N,N-二取代的α-氨基酸缀合的亲电二肽类似物,作为胰蛋白酶样丝氨酸蛋白酶的抑制剂。
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