STABLE METRONIDAZOLE GEL FORMULATIONS
    33.
    发明申请
    STABLE METRONIDAZOLE GEL FORMULATIONS 审中-公开
    稳定的地塞米松凝胶配方

    公开(公告)号:US20100105750A1

    公开(公告)日:2010-04-29

    申请号:US12605008

    申请日:2009-10-23

    IPC分类号: A61K31/4164 A61P17/00

    摘要: The invention provides aqueous gel compositions comprising metronidazole, benzyl alcohol as a solvent, water, and a polyacrylic acid or cellulosic gelling agent, wherein the benzyl alcohol is present in an amount effective to maintain the physical stability of the aqueous gel composition for at least seven days at 5° C. The invention also provides methods of using and methods of preparing the aqueous gel compositions.

    摘要翻译: 本发明提供包含甲硝唑,苄醇作为溶剂的水性水凝胶组合物,水和聚丙烯酸或纤维素胶凝剂,其中苄醇以有效维持水凝胶组合物的物理稳定性至少为7的量存在 在5℃的天。本发明还提供使用方法和制备水性凝胶组合物的方法。