公开(公告)号：US20150101393A1

公开(公告)日：2015-04-16

申请号：US14507310

申请日：2014-10-06

Applicant: Waters Technologies Corporation

Inventor： Michael O. Fogwill ,  Joseph D. Michienzi ,  James P. Murphy

IPC: G01N30/38 ,  G01N33/00 ,  G01F1/76 ,  G01N1/28

CPC classification number: G01N30/38 ,  G01F1/76 ,  G01N1/28 ,  G01N30/68 ,  G01N33/0016 ,  G01N2001/002 ,  G01N2030/324 ,  Y02E20/328

Abstract: Methods and apparatus for the modulation of flame gas stoichiometry to a flame-based detector for use in chromatographic separations are presented. As the total mass flow rate of mobile phase entering the flame-based detector changes (e.g., as a result of density programming in the separation), the mass flow rate of combustion gases to the detector are altered in proportion to the amount of mobile phase entering the detector. As a result, flame stability and sensitivity of the detector can be maintained by the methods and apparatus of the present disclosure.

Abstract translation: 介绍了用于将色谱分离中用于火焰气体检测器的火焰气体化学计量的方法和装置。 随着进入基于火焰的检测器的流动相的总质量流量的变化（例如，由于分离中的密度规划），到检测器的燃烧气体的质量流量与流动相的量成比例地改变 进入检测器 结果，通过本公开的方法和装置可以保持检测器的火焰稳定性和灵敏度。