公开(公告)号：US20130109030A1

公开(公告)日：2013-05-02

申请号：US13808125

申请日：2011-07-04

申请人： Wilhelmina Maria Hardeman ,  Toon Hendrik Evers ,  Theodorus Petrus Henricus Gerardus Jansen

发明人： Wilhelmina Maria Hardeman ,  Toon Hendrik Evers ,  Theodorus Petrus Henricus Gerardus Jansen

IPC分类号： G01N21/75

CPC分类号： G01N21/75 ,  B01L3/502715 ,  B01L2200/027 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2400/0406 ,  B01L2400/0487 ,  G01N33/54366

摘要： The invention relates to a cartridge(10) and its use in an examination apparatus(100). A sample(1) can be introduced into an inlet(11) of the cartridge(10) and conducted through a channel(12) to a reaction chamber(13). In the reaction chamber(13), an examination of the sample takes place, for example by frustrated total internal reflection. An agent(21) is applied to the sample close to the inlet(11), wherein said agent(21) is preferably stored in a reservoir(16) at the inlet(11). In this way the filling time of the reaction chamber(13) is simultaneously used for the incubation of the sample with the agent(21). Moreover, the filling-course of the cartridge and/or the reaction chamber may preferably be determined and taken into account during the execution of the examination and/or the evaluation of the results.

摘要翻译： 本发明涉及一种盒（10）及其在检查装置（100）中的应用。 样品（1）可以被引入到药筒（10）的入口（11）中并且通过通道（12）传导到反应室（13）。 在反应室（13）中，例如通过沮丧的全内反射来检查样品。 将试剂（21）施加到靠近入口（11）的样品上，其中所述试剂（21）优选储存在入口（11）处的储存器（16）中。 以这种方式，反应室（13）的填充时间同时用于样品与试剂（21）的孵育。 此外，可以在执行检查和/或评估结果期间优选地确定和考虑盒和/或反应室的填充过程。

公开(公告)号：US20120250005A1

公开(公告)日：2012-10-04

申请号：US13498482

申请日：2010-09-23

申请人： Johannes Joseph Hubertina Barbara Schleipen ,  Joannes Baptist Adrianus Dionisius Van Zon ,  Derk Jan Wilfred Klunder ,  Toon Hendrik Evers ,  Josephus Arnoldus Henricus Maria Kahlman ,  Ron Martinus Laurentius Van Lieshout ,  Mikhail Mikhaylovich Ovsyanko

发明人： Johannes Joseph Hubertina Barbara Schleipen ,  Joannes Baptist Adrianus Dionisius Van Zon ,  Derk Jan Wilfred Klunder ,  Toon Hendrik Evers ,  Josephus Arnoldus Henricus Maria Kahlman ,  Ron Martinus Laurentius Van Lieshout ,  Mikhail Mikhaylovich Ovsyanko

IPC分类号： G01N21/49 ,  G01R33/12

CPC分类号： G01N33/54373 ,  G01N15/10 ,  G01N15/1031 ,  G01N21/47 ,  G01N21/49 ,  G01N21/51 ,  G01N21/552 ,  G01N21/6458 ,  G01N27/72 ,  G01N33/54313 ,  G01N2015/0065 ,  G01N2201/12 ,  G01R33/1269

摘要： The present invention is related to a biosensor system for the detection of particles comprising: a biosensor cartridge comprising a sensor surface, a biosensor magnet assembly on one side of the cartridge for generating a magnetic field effective at the cartridge and the sensor surface, the first biosensor magnet assembly comprising at least two magnetic sub-units separated by a gap, a first optical detection system for detecting the particles arranged at the same side of the cartridge as the magnet assembly, whereas the magnet assembly is designed in a way that the optical detection is accomplished through the gap of the magnet assembly.

摘要翻译： 本发明涉及一种用于检测颗粒的生物传感器系统，包括：生物传感器盒，包括传感器表面，在盒的一侧上的生物传感器磁体组件，用于产生在盒和感测器表面有效的磁场;第一 生物传感器磁体组件，其包括由间隙分隔开的至少两个磁性子单元;第一光学检测系统，用于检测与磁体组件位于盒的同一侧的颗粒，而磁体组件设计成使得光学 通过磁体组件的间隙实现检测。