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    EXAMINATION SYSTEM WITH SAMPLE INCUBATION
    1.
    发明申请
    EXAMINATION SYSTEM WITH SAMPLE INCUBATION 审中-公开
    检验系统与样本孵化

    公开(公告)号：US20130109030A1

    公开(公告)日：2013-05-02

    申请号：US13808125

    申请日：2011-07-04

    申请人： Wilhelmina Maria Hardeman ,  Toon Hendrik Evers ,  Theodorus Petrus Henricus Gerardus Jansen

    发明人： Wilhelmina Maria Hardeman ,  Toon Hendrik Evers ,  Theodorus Petrus Henricus Gerardus Jansen

    IPC分类号： G01N21/75

    CPC分类号： G01N21/75 ,  B01L3/502715 ,  B01L2200/027 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2400/0406 ,  B01L2400/0487 ,  G01N33/54366

    摘要： The invention relates to a cartridge(10) and its use in an examination apparatus(100). A sample(1) can be introduced into an inlet(11) of the cartridge(10) and conducted through a channel(12) to a reaction chamber(13). In the reaction chamber(13), an examination of the sample takes place, for example by frustrated total internal reflection. An agent(21) is applied to the sample close to the inlet(11), wherein said agent(21) is preferably stored in a reservoir(16) at the inlet(11). In this way the filling time of the reaction chamber(13) is simultaneously used for the incubation of the sample with the agent(21). Moreover, the filling-course of the cartridge and/or the reaction chamber may preferably be determined and taken into account during the execution of the examination and/or the evaluation of the results.

    摘要翻译： 本发明涉及一种盒（10）及其在检查装置（100）中的应用。 样品（1）可以被引入到药筒（10）的入口（11）中并且通过通道（12）传导到反应室（13）。 在反应室（13）中，例如通过沮丧的全内反射来检查样品。 将试剂（21）施加到靠近入口（11）的样品上，其中所述试剂（21）优选储存在入口（11）处的储存器（16）中。 以这种方式，反应室（13）的填充时间同时用于样品与试剂（21）的孵育。 此外，可以在执行检查和/或评估结果期间优选地确定和考虑盒和/或反应室的填充过程。

    MULTI EPITOPE ASSAY
    4.
    发明申请
    MULTI EPITOPE ASSAY 有权
    多重抗生素测定

    公开(公告)号：US20130095495A1

    公开(公告)日：2013-04-18

    申请号：US13704258

    申请日：2011-06-14

    申请人： Gwenola Sabatte ,  Menno Willem Jose Prins ,  Toon Hendrik Evers ,  Wilhelmina Maria Hardeman ,  Joukje Garrelina Orsel

    发明人： Gwenola Sabatte ,  Menno Willem Jose Prins ,  Toon Hendrik Evers ,  Wilhelmina Maria Hardeman ,  Joukje Garrelina Orsel

    IPC分类号： G01N33/53

    CPC分类号： G01N33/5306 ,  G01N33/54306 ,  G01N33/54333

    摘要： The present invention is related to a method for detection of a biological target in an affinity assay, the method comprising the steps of providing a biological sample volume containing the biological target, adding a first capturing moiety to the biological sample volume comprising the biological target, wherein the first capturing moiety is adhered to a particle, concentration of the captured biological target into an elution volume that is smaller than the biological sample volume in step a), cleavage of the first capturing moiety or the biological target from the particle and direct or indirect detection and/or quantification of the biological target in a sandwich or competitive affinity assay format, wherein the biological target is associated with at least one capturing moiety, preferably at least two capturing moieties.

    摘要翻译： 本发明涉及亲和测定中生物靶标检测方法，该方法包括以下步骤：提供含生物靶的生物样品体积，向包含生物靶标的生物样品体积添加第一捕获部分， 其中所述第一捕获部分被粘附到颗粒上，所捕获的生物靶的浓度在步骤a）中小于生物样品体积的洗脱体积，从所述颗粒切割所述第一捕获部分或所述生物靶，并直接或 间接检测和/或以三明治或竞争亲和测定格式定量生物学靶标，其中生物靶标与至少一个捕获部分，优选至少两个捕获部分相关联。