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公开(公告)号：US20210251988A1
公开(公告)日：2021-08-19
申请号：US17254046
申请日：2019-06-20
Applicant: Foghorn Therapeutics Inc.
Inventor： Qianhe ZHOU , Michael BOCKER , Ho Man CHAN , Luis SOARES
IPC: A61K31/496 , A61K31/704 , A61K31/675 , A61K38/46 , C12N15/113 , A61P35/00 , A61K47/54 , A61K45/06 , A61K31/454 , A61K31/427 , A61K31/472
Abstract: The present invention relates to methods and compositions for the treatment of BAF-related disorders such as cancers and viral infections.
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公开(公告)号：US20250085300A1
公开(公告)日：2025-03-13
申请号：US18292508
申请日：2022-07-28
Applicant: FOGHORN THERAPEUTICS INC.
Inventor： Liyue HUANG , David B. TERRY , Joshua D. WAETZIG , Chong-Hui GU
IPC: G01N33/94 , C07D519/00 , G01N33/68
Abstract: Chiral glutarimide stereochemical identity-preserving methods and compositions are disclosed. Also disclosed are methods of preparing chiral glutarimides stereoretentively.
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公开(公告)号：US20250066354A1
公开(公告)日：2025-02-27
申请号：US18926578
申请日：2024-10-25
Applicant: Foghorn Therapeutics Inc.
Inventor： Shawn E.R. SCHILLER , Solymar NEGRETTI , David S. HUANG , Kevin J. WILSON , Melek Nihan UCISIK , Richard CALDWELL
IPC: C07D471/04 , A61K45/06 , C07D519/00
Abstract: The present disclosure features compounds of Formula I, or pharmaceutically acceptable salts thereof, and formulations containing the same. Methods of treating BAF complex-related disorders, such as cancer, are also disclosed.
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公开(公告)号：US12139487B2
公开(公告)日：2024-11-12
申请号：US18315526
申请日：2023-05-11
Applicant: Foghorn Therapeutics Inc.
Inventor： Shawn E. R. Schiller , Solymar Negretti , David S. Huang , Kevin J. Wilson , Melek Nihan Ucisik , Richard Caldwell
IPC: C07D471/04 , A61K45/06 , C07D519/00
Abstract: The present disclosure features compounds of Formula I, or pharmaceutically acceptable salts thereof, and formulations containing the same. Methods of treating BAF complex-related disorders, such as cancer, are also disclosed.
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公开(公告)号：US20240158387A1
公开(公告)日：2024-05-16
申请号：US18281022
申请日：2022-03-09
Applicant: FOGHORN THERAPEUTICS INC.
Inventor： Rishi G. VASWANI , Chong-Hui GU
IPC: C07D417/14 , A61K9/48 , A61K45/06
CPC classification number: C07D417/14 , A61K9/4816 , A61K9/4858 , A61K9/4866 , A61K45/06 , C07B2200/13
Abstract: Disclosed are crystalline forms of the compound of formula (I): (I) Also disclosed are compositions containing the crystalline forms of the compound of formula (I) and methods of their use. The methods may be for treating cancer in a subject in need thereof, e.g., by administering to the subject an effective amount of the crystalline form disclosed herein or its composition.
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Patent Agency Ranking
公开(公告)号：US20240150328A1
公开(公告)日：2024-05-09
申请号：US18454594
申请日：2023-08-23
Applicant: FOGHORN THERAPEUTICS INC.
Inventor： Qianhe ZHOU , Michael BOCKER , David Simon MILLAN , Ho Man CHAN , Luis SOARES , Matthew NETHERTON , Sabine K. RUPPEL , Zhaoxia YANG , Jason T. LOWE , Francois BRUCELLE
IPC: C07D403/14 , A61K9/16 , A61K45/06 , A61P35/00
CPC classification number: C07D403/14 , A61K9/1605 , A61K45/06 , A61P35/00
Abstract: The present invention relates to methods and compositions for the treatment of BAF-related disorders such as cancers and viral infections.
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公开(公告)号：US20240101534A1
公开(公告)日：2024-03-28
申请号：US18253526
申请日：2021-11-22
Applicant: Foghorn Therapeutics Inc.
Inventor： Matthew NETHERTON , Francois BRUCELLE , Jing DENG , Johannes H. VOIGT
IPC: C07D401/14 , C07D487/10 , C07D417/14 , C07D471/10 , A61P35/00
CPC classification number: C07D401/14 , C07D487/10 , C07D417/14 , C07D471/10 , A61P35/00
Abstract: The present disclosure features compounds and methods useful for the treatment of BAF complex-related disorders.
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公开(公告)号：US20230416246A1
公开(公告)日：2023-12-28
申请号：US18216392
申请日：2023-06-29
Applicant: FOGHORN THERAPEUTICS INC.
Inventor： Sabine K. RUPPEL , Zhaoxia YANG , Jason T. LOWE , Johannes H. VOIGT , Matthew NETHERTON
IPC: C07D471/04 , C07D498/10 , C07D519/00 , C07D401/14 , A61P35/00 , C07D471/10 , C07D487/04 , C07D487/10
CPC classification number: C07D471/04 , C07D498/10 , C07D519/00 , C07D401/14 , A61P35/00 , C07D471/10 , C07D487/04 , C07D487/10
Abstract: The present invention relates to compositions and methods for the treatment of BAF-related disorders, such as cancers and viral infections.
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公开(公告)号：US20230348452A1
公开(公告)日：2023-11-02
申请号：US17795615
申请日：2021-01-29
Applicant: Foghorn Therapeutics Inc.
Inventor： Matthew NETHERTON , Shawn E.R. SCHILLER , Jing DENG , Neville John ANTHONY , Francois BRUCELLE , Sabine K. RUPPEL , Johannes H. VOIGT
IPC: C07D417/14 , C07D471/10
CPC classification number: C07D417/14 , C07D471/10
Abstract: The present disclosure features compounds and methods useful for the treatment of BAF complex-related disorders.
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公开(公告)号：US20230142883A1
公开(公告)日：2023-05-11
申请号：US17933330
申请日：2022-09-19
Applicant: Foghorn Therapeutics Inc.
Inventor： Sabine K. RUPPEL , Zhaoxia Yang , Jason T. Lowe , Johannes H. Voigt , Matthew Russell Netherton
IPC: C07D471/04 , C07D401/14 , C07D498/10 , C07D519/00
CPC classification number: C07D471/04 , C07D401/14 , C07D498/10 , C07D519/00
Abstract: The present invention relates to compositions and methods for the treatment of BAF-related disorders, such as cancers and viral infections.
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