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公开(公告)号:US20230072053A1
公开(公告)日:2023-03-09
申请号:US17795985
申请日:2021-01-29
IPC分类号: C07D495/04 , A61P35/00
摘要: The present disclosure features compounds useful for the treatment of BAF complex-related disorders.
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公开(公告)号:US11497752B2
公开(公告)日:2022-11-15
申请号:US16965822
申请日:2019-01-29
IPC分类号: C07D277/00 , C07D417/00 , A61K31/00 , A61K31/541 , A61P35/04 , A61K31/427 , A61K31/4409 , A61K31/4425 , A61K31/4439 , A61K31/4709 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K45/06 , C07D277/46 , C07D417/04 , C07D417/10 , C07D417/14
摘要: The present disclosure features compounds useful for the treatment of BAF complex-related disorders.
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公开(公告)号:US20220119378A1
公开(公告)日:2022-04-21
申请号:US17425041
申请日:2020-01-29
IPC分类号: C07D417/14 , A61P35/00 , C07D471/04
摘要: The present disclosure features compounds useful for the treatment of BAF complex-related disorders.
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公开(公告)号:US20210260171A1
公开(公告)日:2021-08-26
申请号:US17253952
申请日:2019-06-20
发明人: Qianhe ZHOU , Michael BOCKER , Ho Man CHAN , Luis SOARES
IPC分类号: A61K38/46 , A61K31/704 , A61K31/675 , C12N15/113 , A61K31/454 , A61K31/427 , A61K31/472 , A61K31/496 , A61P35/00 , C12N15/11
摘要: The present invention relates to methods and compositions for the treatment of BAF-related disorders such as cancers and viral infections.
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公开(公告)号:US20210171958A1
公开(公告)日:2021-06-10
申请号:US17270170
申请日:2019-08-23
发明人: Ho Man CHAN , Qianhe ZHOU , Luis SOARES
IPC分类号: C12N15/113 , A61P35/00 , C12N9/22 , A61K45/06
摘要: The present disclosure features useful methods to treat cancer having a deficiency in ARID1 A and/or mismatch repair deficiency, e.g., in a subject in need thereof. In some embodiments, the methods described herein are useful in the treatment of cancer in combination with immunotherapies.
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公开(公告)号:US20230129003A1
公开(公告)日:2023-04-27
申请号:US17963576
申请日:2022-10-11
发明人: Rishi G. VASWANI , David S. HUANG
IPC分类号: C07D417/14 , A61P35/02 , A61P35/00
摘要: The present disclosure features compounds useful for the treatment of BAF complex-related disorders.
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公开(公告)号:US20230064136A1
公开(公告)日:2023-03-02
申请号:US17858875
申请日:2022-07-06
发明人: Chong-Hui GU , Joshua D. WAETZIG
IPC分类号: C07D519/00
摘要: The present disclosure features citrate salts and pharmaceutical compositions useful for the treatment of BAF complex-related disorders. Also disclosed are methods for preparing compounds.
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公开(公告)号:US20220289711A1
公开(公告)日:2022-09-15
申请号:US17631791
申请日:2020-07-31
发明人: Sabine K. RUPPEL , Zhaoxia YANG , Jason T. LOWE
IPC分类号: C07D401/14 , C07D471/04 , C07D471/10 , C07D487/04
摘要: The present disclosure features compounds useful for the treatment of BAF complex-related disorders.
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公开(公告)号:US20220079940A1
公开(公告)日:2022-03-17
申请号:US17325937
申请日:2021-05-20
发明人: Richard C. CENTORE , Lan XU , David LAHR , Ammar ADAM
IPC分类号: A61K31/501 , A61K45/06 , A61P35/04 , A61P35/02
摘要: The present invention relates to methods and compositions for the treatment of BAF-related disorders such as acute myeloid leukemia.
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公开(公告)号:US20230079819A1
公开(公告)日:2023-03-16
申请号:US17425140
申请日:2020-01-29
发明人: Rishi G. VASWANI , Neville John ANTHONY , David Simon MILLAN , Shawn E.R. SCHILLER , Kevin J. WILSON , David S. HUANG
IPC分类号: C07D417/14 , A61P35/00 , C07D498/04 , C07D417/12 , C07D487/04 , C07D491/08 , C07D471/04 , C07D491/107 , C07D491/048
摘要: The present disclosure features compounds useful for the treatment of BAF complex-related disorders.
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