公开(公告)号：US3776901A

公开(公告)日：1973-12-04

申请号：US3776901D

申请日：1968-04-01

Applicant: GULF RESEARCH DEVELOPMENT CO

Inventor： KELLY K ,  MATTHEWS J

IPC: C07D201/04 ,  C07D41/06

CPC classification number: C07D201/04

Abstract: A METHOD FOR CONVERTING A KETOXIME TO AN N-SUBSTITUTED AMIDE BY REACTING A KETOXIME WITH A COMPLEX OF AN NSUBSTITUTED CARBOXYLIC ACID AMIDE AND SULFUR TRIOXIDE TO FORM A NOVEL COMPOUND OF THE KETOXIME, CARBOXYLIC ACID AMIDE AND SULFUR TRIOXIDE AND DECOMPOSING THIS COMPOUND TO PRODUCE AN N-SUBSTITUTED AMIDE CORRESPONDING TO THE KETOXIME. CYCLOHEXANONE OXIME IS CONVERTED TO CAPROLACTAM.

公开(公告)号：US3767647A

公开(公告)日：1973-10-23

申请号：US3767647D

申请日：1971-01-11

Applicant: TOA GOSEI CHEM IND

Inventor： HIROSE T ,  MATSUBARA T

IPC: C07D201/04 ,  C07D41/00

CPC classification number: C07D201/04

Abstract: A HIGH PURITY W-LAUROLACTAM IS PREPARED FROM A CRUDE CYCLODODECANONE OXIME CONTAINING 5% BY WEIGHT OR LESS OF CYCLODODECANONE BY SUBJECTING THE OXIME TO THE BECKMANN REARRANGEMENT REACTION IN THE PRESENCE OF SULFURIC ACID HAVING A CONCENTRATION OF 98% BY WEIGHT OR MORE OR FUMING SULFURIC ACID CONTAINING 20% BY WEIGHT OR LESS OF SULFURIC-ANHYDRIDE, SEPARATING THE THUS FORMED W-LAUROLACTAM FROM THE REACTION MIXTURE, DISSOLVING THE RESULTING W-LAUROLACTAM N A LIQUID AROMATIC HYDROCARBON, WASHING THE SOLUTION WITH AN ALKALI SOLUTION AT A TEMPERATURE OF 60* TO 120* C., AND RECOVERING W-LAUROLACTAM.

公开(公告)号：US3757007A

公开(公告)日：1973-09-04

申请号：US3757007D

申请日：1971-08-10

Applicant: KANEGAFUCHI SPINNING CO LTD

Inventor： DEGUCHI S ,  FUJITA I ,  YONEYA T

IPC: C07C67/00 ,  C07C239/00 ,  C07C251/46 ,  C07D201/02 ,  C07D201/04 ,  C07D41/06

CPC classification number: C07D201/02 ,  C07D201/04

Abstract: A PROCESS FOR PRODUCING E-CAPROLACTAM AND O-ACETYLCYCLOHEXANONE OXIME COMPRISING REACTING 0.01 TO 100 MOLS OF CYCLOHEXANONE OXIME WITH ONE MOL OF N-ACETYLCAPROLACTAM AT A TEMPERATURE OF 30 TO 120*C. FOR 10 MINUTES TO 100 HOURS IN THE PRESENCE OF AN AORGANIC SOLVENT IN AN AMOUNT OF 0 TO 20 TIMES THE TOTAL WEIGHT OF N-ACETYLCAPROLACTAM AND CYCLOHEXANONE OXIME.

公开(公告)号：US3428625A

公开(公告)日：1969-02-18

申请号：US3428625D

申请日：1966-09-23

Applicant: HUELS CHEMISCHE WERKE AG

Inventor： STRAUSS GUNTHER

IPC: C07D201/04 ,  C07D41/06

CPC classification number: C07D201/04

公开(公告)号：US20230020512A1

公开(公告)日：2023-01-19

申请号：US17782244

申请日：2020-10-27

Applicant: HANWHA SOLUTIONS CORPORATION

Inventor： Jinho PARK ,  Jiyeon KIM ,  Hyun SEO ,  Namjin JANG

IPC: C07D201/04 ,  C07D225/02

Abstract: Provided are a method of preparing laurolactam including: a) synthesizing laurolactam by Bechmann rearrangement of cyclododecanone oxime under a catalyst system, b) mixing the laurolactam synthesized in a) with a good solvent and removing the catalyst system, and c) mixing the laurolactam from which the catalyst system has been removed in b) with a poor solvent and performing recrystallization, a synthesis device thereof, a laurolactam composition prepared therefrom, and a method of preparing polylaurolactam using the laurolactam composition.

公开(公告)号：US20220024868A1

公开(公告)日：2022-01-27

申请号：US17311353

申请日：2019-12-18

Applicant: HANWHA SOLUTIONS CORPORATION

Inventor： Jiyeon KIM ,  Youngjin KIM ,  Jeongseok PARK ,  Jinho PARK ,  Hyun SEO ,  Seonghoon HYEONG ,  Kyuho SONG

IPC: C07D201/04

Abstract: The present invention relates to a laurolactam preparation method and synthesis apparatus, and epoxidation and a rearrangement reaction are performed in the conversion of cyclododecene into cyclododecanone so that the preparation method can synthesize laurolactam having a higher purity with a higher selectivity and in a higher yield than a conventional preparation method.

公开(公告)号：US20220001364A1

公开(公告)日：2022-01-06

申请号：US17208535

申请日：2021-03-22

Applicant: ZHEJIANG HENGLAN SCIENCE & TECHNOLOGY CO., LTD.

Inventor： Shibiao CHENG ,  Songlin WANG ,  Fei SHEN ,  Han WANG ,  Yixuan HE ,  Zhaobin JIANG ,  Zhimin HU

IPC: B01J29/76 ,  C07D201/04 ,  B01J29/78 ,  C01B39/48 ,  B01J35/02 ,  B01J21/08 ,  B01J37/04 ,  B01J37/08 ,  C07D223/10 ,  B01J29/70 ,  B01J35/10 ,  B01J37/00 ,  B01J37/06

Abstract: The present disclosure discloses a MFI topological structure silicon molecular sieve, a preparation method thereof and a catalyst containing the MFI topological structure silicon molecular sieve, wherein the molecular sieve containing a silicon element, an oxygen element and a metallic element, the ions of said metallic element have a Lewis acid characteristic; the content of the metallic element in the molecular sieve is within a range of 5-100 μg/g based on the total amount of the molecular sieve; the BET specific surface area of the molecular sieve is within a range of 400-500 m2/g.

公开(公告)号：US10093622B2

公开(公告)日：2018-10-09

申请号：US15562518

申请日：2015-06-04

Applicant: ANTHEA AROMATICS PRIVATE LIMITED

Inventor： Manoj Kumar Mohapatra ,  Ramamohanrao Bendapudi ,  Paul Vincent Menacherry ,  Vincent Paul

IPC: C07D201/04 ,  C07D201/06 ,  C01B21/14 ,  C01G9/02 ,  C07D201/16 ,  C07D227/087 ,  B01D3/36

Abstract: Disclosed herein is an efficient, economical, industrially advantageous, straight-through process for the preparation of cyclic amides, also referred as lactams, in substantially pure form and high yield, from the corresponding cyclic ketones and a hydroxylammonium salt, using a combination of amphoteric metal oxide or amphoteric masked metal oxide and a base.

公开(公告)号：US09708270B2

公开(公告)日：2017-07-18

申请号：US14434524

申请日：2013-10-11

Applicant: Merck Sharp & Dohme Corp.

Inventor： Mariappan Chelliah ,  Hong Dong Chu ,  Jason M. Cox ,  John S. Debenham ,  Keith Eagen ,  Ping Lan ,  Clare London ,  Michael A. Plotkin ,  Unmesh Shah ,  Christopher Joseph Sinz ,  Zhongxiang Sun ,  Henry M. Vaccaro ,  Srikanth Venkatraman

IPC: C07D401/12 ,  C07D491/107 ,  C07D221/20 ,  C07D201/04 ,  C07D401/04 ,  C07D405/10

CPC classification number: C07D221/20 ,  C07D401/04 ,  C07D401/12 ,  C07D405/10 ,  C07D491/107

Abstract: The present invention relates to a compound represented by formula (I): and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing diabetes, hyperlipidemia, obesity, inflammation related disorders, and related diseases and conditions. The compounds are useful as agonists of the G-protein coupled receptor GPR120. Pharmaceutical compositions and methods of treatment are also included.

公开(公告)号：US20150353478A1

公开(公告)日：2015-12-10

申请号：US14655514

申请日：2013-12-12

Applicant: SUMITOMO CHEMICAL COMPANY, LIMITED

Inventor： Masahiro HOSHINO ,  Yuta KIKUCHI ,  Sho TSUJIUCHI

IPC: C07C249/04 ,  C07D201/04

CPC classification number: C07C249/04 ,  C07C2601/14 ,  C07D201/04 ,  C07C251/44

Abstract: Provided is a method for producing an oxime compound with satisfactory selectivity. Provide is a method for producing an oxime represented by the following formula (II): wherein R1 and R2 are respectively the same as defined below, the method including oxidizing an amine represented by the following formula (I): wherein R1 and R2 each independently represents a hydrogen atom, an optionally substituted hydrocarbon group, or an optionally substituted heterocyclic group (provided that R1 and R2 are not simultaneously hydrogen atoms), orR1 and R2, together with the carbon atom to which R1 and R2 are attached, form an optionally substituted alicyclic hydrocarbon group having 3 to 12 carbon atoms [hereinafter sometimes referred to as the amine compound (I)],with oxygen in the presence of a layered silicate.

Abstract translation: 提供一种具有令人满意的选择性的肟化合物的制造方法。 提供一种生产由下式（II）表示的肟的方法：其中R1和R2分别与下述定义相同，该方法包括氧化由下式（I）表示的胺：其中R1和R2各自独立地 表示氢原子，任选取代的烃基或任选取代的杂环基（条件是R 1和R 2不同时为氢原子），或者R 1和R 2与连接R 1和R 2的碳原子一起形成 任选取代的具有3〜12个碳原子的脂环族烃基[以下有时称为胺化合物（I）]与层状硅酸盐存在下的氧。