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公开(公告)号：US11179254B2
公开(公告)日：2021-11-23
申请号：US16196221
申请日：2018-11-20
发明人： Jennifer K. White
摘要： A prosthetic heart valve can include an inner support structure, a valve member, and an outer support structure. The inner support structure can have a plurality of first struts coupled together by first pivot joints and forming a first lumen. The valve member can be disposed within the first lumen and coupled to the inner support structure. The valve member can include a plurality of leaflets configured for permitting blood flow through the valve member in one direction. The outer support structure can have a plurality of second struts coupled together by second pivot joints and can form an annulus portion, an outflow portion, and a second lumen. The outflow portion can extend radially outwardly relative to the annulus portion, and the inner support structure and the valve member can be disposed within the second lumen and be coupled to the outer support structure.
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公开(公告)号：US20210322160A1
公开(公告)日：2021-10-21
申请号：US17359242
申请日：2021-06-25
发明人： Christoph Hans Huber
IPC分类号： A61F2/24 , A61B17/22 , A61B17/32 , A61B17/34 , A61F2/07 , A61F2/856 , A61F2/90 , A61F2/01 , A61B17/00
摘要： A method for implanting a replacement heart valve within a diseased valve includes accessing a patient's heart by piercing a myocardium, advancing a guidewire into the patient's heart, and installing an access device in a wall of the heart. The access device preferably has at least one valve mechanism. A valve delivery device is advanced over the guidewire and through the access device. The valve delivery device has a replacement heart valve disposed along a distal end portion thereof. The replacement heart valve preferably includes an outer support structure and a leaflet valve disposed within the outer support structure. The replacement heart valve is radially expanded within the diseased valve. During implantation, the outer support structure conforms to a diameter of the diseased valve and the leaflet valve expands to a fixed size having a diameter smaller than the diameter of the diseased valve.
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公开(公告)号：US11083576B2
公开(公告)日：2021-08-10
申请号：US16275769
申请日：2019-02-14
发明人： Richard George Cartledge , Derek Dee Deville , Kevin W. Smith , James L. Greene , Jorge H. Jimenez
IPC分类号： A61F2/24
摘要： A method of implanting a replacement mitral valve can include expanding a replacement mitral valve to a first expanded configuration. The replacement mitral valve can include a force-expanding mitral valve lattice and a self-expanding valve trampoline lattice. The mitral valve lattice has an inflow end portion and an outflow end portion, and the valve trampoline lattice is attached to the outflow end portion of the mitral valve lattice. The method can also include rotating a plurality of jack screws connected to the mitral valve lattice. The jack screws can be configured to expand the mitral valve lattice from the first expanded configuration to a second expanded configuration.
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公开(公告)号：US10925760B2
公开(公告)日：2021-02-23
申请号：US16222924
申请日：2018-12-17
摘要： A prosthetic implant includes a circumferentially adjustable sealing collar and a rotatable sealer gear. The sealing collar has a central longitudinal axis. The rotatable sealer gear is coupled to and disposed within the sealing collar and configured to adjust the circumference of the sealing collar. The sealer gear is radially offset relative to the central longitudinal axis of the sealing collar. Rotating the sealer gear in a first direction relative to the sealing collar circumferentially expands the sealing collar. Rotating the sealer gear in a second direction relative to the sealing collar circumferentially contracts the sealing collar.
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公开(公告)号：US20200170812A1
公开(公告)日：2020-06-04
申请号：US16785502
申请日：2020-02-07
发明人： Jennifer K. White
摘要： A prosthetic heart valve includes a frame, a valve component, and an actuation mechanism. The frame has a plurality of struts interconnected by a plurality of joints and is movable between expanded and compressed configurations. The valve component is inside the frame and has a plurality of leaflets. The actuation mechanism has a first expansion element coupled to the frame at a first location and a second expansion element coupled to the frame at a second location. The actuation mechanism is configured such that moving the first expansion element and the second expansion element toward each other in a first direction results in the frame moving from the compressed configuration to the expanded configuration, and such that moving the first expansion element and the second expansion element away from each other in a second direction results in the frame moving from the expanded configuration to the compressed configuration.
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公开(公告)号：US20200170788A1
公开(公告)日：2020-06-04
申请号：US16783868
申请日：2020-02-06
发明人： J. Brent Ratz , Arshad Quadri , Luca Pesce
IPC分类号： A61F2/24
摘要： A prosthesis can comprise an expandable frame, a plurality of distal anchors and a plurality of proximal anchors. The anchors can extend outwardly from the frame. The frame can be configured to radially expand and contract for deployment within a body cavity. The frame and anchors can have one of many different shapes and configurations. For example, when the frame is in an expanded configuration, the frame can have a larger cross-sectional dimension in a middle portion of the frame and a smaller cross-sectional dimension in a proximal portion and a distal portion of the frame, wherein the middle portion is between the proximal and distal portions. As another example, the anchors can have looped ends, the entire anchor may loop out from the frame.
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公开(公告)号：US10646334B2
公开(公告)日：2020-05-12
申请号：US15979271
申请日：2018-05-14
发明人： Arshad Quadri , J. Brent Ratz
摘要： A method of deploying a prosthesis within a native mitral valve is disclosed. The expandable frame preferably includes about twelve proximal anchors, wherein the proximal anchors have free ends positioned radially outwardly from the frame in an expanded configuration. The expandable frame preferably includes about twelve distal anchors, wherein the distal anchors also have a free ends positioned radially outwardly from the frame and extend toward a proximal end when the frame is in the expanded configuration. A valve body is supported within the frame for preventing blood flow in one direction. The expandable frame is radially expanded during deployment, which causes the free ends of the proximal and distal anchors to move closer together. In the expanded configuration, the proximal anchors are positioned on an inflow side of the native mitral valve and the distal anchors are positioned on an outflow side of the native mitral valve.
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公开(公告)号：US10583000B2
公开(公告)日：2020-03-10
申请号：US15947168
申请日：2018-04-06
发明人： J. Brent Ratz , Arshad Quadri , Luca Pesce
IPC分类号： A61F2/24
摘要： A prosthesis can comprise an expandable frame, a plurality of distal anchors and a plurality of proximal anchors. The anchors can extend outwardly from the frame. The frame can be configured to radially expand and contract for deployment within a body cavity. The frame and anchors can have one of many different shapes and configurations. For example, when the frame is in an expanded configuration, the frame can have a larger cross-sectional dimension in a middle portion of the frame and a smaller cross-sectional dimension in a proximal portion and a distal portion of the frame, wherein the middle portion is between the proximal and distal portions. As another example, the anchors can have looped ends, the entire anchor may loop out from the frame.
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49.发明申请公开(公告)号：US20190336285A1
公开(公告)日：2019-11-07
申请号：US16517070
申请日：2019-07-19
发明人： Arshad Quadri , J. Brent Ratz , Yen Liao , Julio Cesar Sanchez , Alexander H. Cooper , Glen T. Rabito , Siddharth Vad , Luca Pesce , Kevin M. Stewart , David Robert Landon
IPC分类号： A61F2/24
摘要： Devices, systems and methods are described herein a prosthesis for implantation within a lumen or body cavity and delivery systems for delivering the prosthesis to a location for implantation. A delivery system can include a plurality of components, including a flexible nose cone, multi-layer sheath, and pre-compressed shaft, which can be moveable relative to each other.
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公开(公告)号：US20190029819A1
公开(公告)日：2019-01-31
申请号：US16150152
申请日：2018-10-02
发明人： Christoph Hans Huber
IPC分类号： A61F2/24 , A61B17/22 , A61B17/32 , A61B17/34 , A61F2/01 , A61F2/07 , A61B17/00 , A61F2/856 , A61F2/90 , A61F2/89 , A61F2/848 , A61B17/3205 , A61B18/00 , A61F2/06 , A61F2/95
摘要： A method for implanting a replacement heart valve within a diseased valve includes accessing a patient's heart by piercing a myocardium, advancing a guidewire into the patient's heart, and installing an access device in a wall of the heart. The access device preferably has at least one valve mechanism. A valve delivery device is advanced over the guidewire and through the access device. The valve delivery device has a replacement heart valve disposed along a distal end portion thereof. The replacement heart valve preferably includes an outer support structure and a leaflet valve disposed within the outer support structure. The replacement heart valve is radially expanded within the diseased valve. During implantation, the outer support structure conforms to a diameter of the diseased valve and the leaflet valve expands to a fixed size having a diameter smaller than the diameter of the diseased valve.
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