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    Temperature Sensor
    41.
    发明申请
    Temperature Sensor 审中-公开

    公开(公告)号：US20180003571A1

    公开(公告)日：2018-01-04

    申请号：US15542986

    申请日：2015-01-14

    Applicant: The University of Adelaide

    Inventor： Tanya Monro ,  Stephen Warren-Smith

    IPC: G01K11/32 ,  G02B6/02

    CPC classification number: G01K11/3206 ,  G02B6/0208 ,  G02B6/02123 ,  G02B6/02314 ,  G02B6/02366 ,  G02B2006/02161

    Abstract: A temperature sensor and temperature sensing system for sensing changes m temperature up to a predetermined temperature is disclosed. The temperature sensor includes a microstructured optical fiber where the micro-structured optical fiber includes a plurality of longitudinal channels extending along the microstructured optical fiber. The sensor also includes a fiber Bragg grating formed in the microstructured optical, fiber by generating a periodic modulation in the refractive index along a core region of the microstructured optical fiber. The fiber Bragg grating is operable to produce band reflection at a reflection wavelength that varies in accordance with changes in temperature at the core region of the optical fiber.

    Microstructured optical fiber sensor
    42.
    发明授权
    Microstructured optical fiber sensor 有权

    公开(公告)号：US12158377B2

    公开(公告)日：2024-12-03

    申请号：US17767244

    申请日：2020-10-08

    Applicant: The University of Adelaide

    Inventor： Stephen Christopher Warren-Smith ,  Heike Ebendorff-Heidepriem ,  Viet Linh Nguyen ,  Erik Peter Schartner

    IPC: G01K11/3206 ,  G02B6/02

    Abstract: A microstructured optical fiber sensor for sensing changes in a physical characteristic up to a predetermined temperature is disclosed. The sensor includes a microstructured optical fiber and a fiber Bragg grating formed in the microstructured optical fiber by generating a periodic modulation in the refractive index along a core region of the suspended core. The fiber Bragg grating is configured to produce a band reflection spectra including a fundamental mode and a plurality of higher order modes whose respective wavelengths vary in accordance with changes in the physical characteristic at the core region of the microstructured optical fiber. The microstructured optical fiber is configured to increase the confinement loss of the plurality of higher order modes of the band reflection spectra relative to the fundamental mode.

    COMBINATION TREATMENT OF CHRONIC MYELOMONOCYTIC LEUKEMIA IN PATIENTS WITH RAS PATHWAY MUTATIONS
    44.
    发明公开
    COMBINATION TREATMENT OF CHRONIC MYELOMONOCYTIC LEUKEMIA IN PATIENTS WITH RAS PATHWAY MUTATIONS 审中-公开

    公开(公告)号：US20240309079A1

    公开(公告)日：2024-09-19

    申请号：US18604466

    申请日：2024-03-13

    Applicant: TARAN THERAPEUTICS, INC. ,  THE UNIVERSITY OF ADELAIDE

    Inventor： Cameron DURRANT ,  Daniel THOMAS ,  Dale CHAPPELL

    IPC: C07K16/24 ,  A61K31/706 ,  A61K31/7072 ,  A61K39/00 ,  A61K39/395 ,  A61P35/02

    CPC classification number: C07K16/243 ,  A61K31/706 ,  A61K31/7072 ,  A61K39/3955 ,  A61P35/02 ,  A61K2039/505 ,  A61K2039/54 ,  A61K2039/545 ,  C07K2317/21

    Abstract: Provided herein are methods for treating a subject having chronic myelomonocytic leukemia (CMML), the method comprising: (a) identifying a RAS pathway mutation in tumor cells of the subject, wherein the RAS pathway mutation is a NRAS, KRAS, and/or CBL mutation; and (b) administering to the subject identified in step (a) a therapeutically effective amount of an anti-hGM-CSF antibody. The subject may have a RAS pathway mutation or a RAS pathway mutation and at least one TET2 mutation identified in the tumor cells. The methods further comprise administering a therapeutically effective amount of a hypomethylating agent. Also provided herein are methods for treating a subject having chronic myelomonocytic leukemia (CMML), the method comprising: (a) identifying a RAS pathway mutation in tumor cells of the subject, wherein the RAS pathway mutation is a NRAS, KRAS, and/or CBL mutation; and (b) administering to the subject identified in step (a) a therapeutically effective amount of an anti-hGM-CSF antibody lenzilumab and a therapeutically effective amount of a hypomethylating agent. The subject may have a RAS pathway mutation or a RAS pathway mutation and at least one TET2 mutation identified in the tumor cells. A therapeutically effective amount of a hypomethylating agent is further administered according to the provided methods.

    METHOD AND APPARATUS FOR ALUMINA CALCINATION
    45.
    发明公开
    METHOD AND APPARATUS FOR ALUMINA CALCINATION 审中-公开

    公开(公告)号：US20240308868A1

    公开(公告)日：2024-09-19

    申请号：US18570800

    申请日：2022-06-17

    Applicant: The University of Adelaide

    Inventor： Woei Lean Saw ,  Graham Jerold Nathan ,  Raymond Victor Chatfield ,  Ross Jeffrey Haywood

    IPC: C01F7/444

    CPC classification number: C01F7/444

    Abstract: An improved apparatus for steam calcining aluminium trihydroxide (Al(OH)3) to produce alumina (Al2O3) is disclosed. The apparatus comprises an Al(OH)3 preheater configured to heat an Al(OH)3feedstock by contacting it with steam. The Al(OH)3 preheater comprises at least one gas solid separator for separating preheated Al(OH)3 from carrier steam. The apparatus further comprises a calciner configured to accept preheated Al(OH)3 from the Al(OH)3 preheater and to produce heated Al2O3 by steam calcination. The apparatus also comprises an Al2O3 cooler configured to remove heat from the heated Al2O3 and produce Al2O3 product. The Al2O3 cooler comprises at least one gas solid separator. The apparatus further comprises a steam compressor in fluid communication with the Al(OH)3 preheater, the calciner and the Al2O3 cooler and configured to accept and pressurise carrier steam from the Al(OH)3preheater and to provide pressurised carrier steam to the Al(OH)3 preheater and pressurised carrier steam the Al2O3 cooler to transfer Al(OH)3 feedstock to and within the Al(OH)3 preheater, and pressurised carrier steam to transfer preheated Al(OH)3 from the Al(OH)3 preheater to the calciner, and to transfer heated Al2O3 from the calciner to and within the Al2O3 cooler.

    PHOTOCATALYTIC APPARATUS
    46.
    发明公开
    PHOTOCATALYTIC APPARATUS 审中-公开

    公开(公告)号：US20240189791A1

    公开(公告)日：2024-06-13

    申请号：US18553343

    申请日：2022-04-05

    Applicant: THE UNIVERSITY OF ADELAIDE ,  FLINDERS UNIVERSITY

    Inventor： Gregory METHA ,  Jason ALVINO ,  Gunther ANDERSSON ,  D.J. OSBORN

    IPC: B01J8/02 ,  C01B3/04

    CPC classification number: B01J8/0278 ,  B01J8/0285 ,  C01B3/042 ,  B01J2208/00212

    Abstract: This disclosure relates to an apparatus and a method for photocatalytically splitting H2O, that is either in liquid or gaseous form, to produce hydrogen and oxygen using a radiation source comprising a spectrum of both a high energy component (such as ultraviolet, or UV, comprising visible light) and a low energy component (such as infrared, or IR, also comprising visible light). That is to say, the apparatus and the method both utilise or involve the entire or full spectrum of the radiation source to split H2O. Both the apparatus and method utilise a radiation concentrator assembly that comprises at least one optical element arranged and constructed to direct radiation from the radiation source on to a photocatalyst via a window to photocatalytically split H2O. The produced hydrogen and oxygen may subsequently be stored and used as a fuel source.

    AN OPTICAL ELEMENT
    47.
    发明公开
    AN OPTICAL ELEMENT 审中-公开

    公开(公告)号：US20230341668A1

    公开(公告)日：2023-10-26

    申请号：US18006373

    申请日：2021-07-23

    Applicant: The University of Adelaide ,  Universität Stuttgart

    Inventor： Jiawen Li ,  Robert McLaughlin ,  Simon Thiele ,  Alois Herkommer ,  Harald Gießen

    IPC: G02B6/26 ,  G02B17/08 ,  G02B23/24 ,  G02B17/00

    CPC classification number: G02B17/0856 ,  G02B6/262 ,  G02B17/006 ,  G02B23/2469 ,  G02B21/0056

    Abstract: An optical element (100) is provided comprising a first surface (102) for emitting and/or receiving electromagnetic radiation, the first surface being arranged for optically coupling to, or being optically coupled to, a portion of an optical fibre (104) having an axis. The optical element (100) comprising a second surface (106) positioned for emitting and/or receiving electromagnetic radiation in a direction transversal to the axis of the optical fibre (104), wherein the optical element (100) has a first focal length for electromagnetic radiation emitted and/or received by an inner portion of the second surface (106) and a second focal length for electromagnetic radiation emitted and/or received by an outer portion of the second surface (106), the first and second focal lengths being different focal lengths. A method of forming an optical device comprising the optical element (100) and further comprising an optical fibre coupled to the optical element is also provided.

    CELL CULTURE MICRODEVICE
    50.
    发明申请
    CELL CULTURE MICRODEVICE 有权

    公开(公告)号：US20230013813A1

    公开(公告)日：2023-01-19

    申请号：US17782625

    申请日：2020-12-03

    Applicant: The University of Adelaide

    Inventor： Jeremy Thompson

    IPC: C12M3/06 ,  C12M1/00 ,  C12M3/00

    Abstract: A cell culture microdevice for maintaining and culturing a cell therein comprising a cell culture unit having at least a first cell carrier unit defining a cell culture chamber formed therein, the first cell carrier unit formed from at least, a chamber base shaped to support the cell thereon, and one or more chamber walls having one or more chamber wall surfaces enclosing the cell culture chamber about a chamber boundary, the first cell carrier unit further providing a guiding surface to guide instruments or fluids into the cell culture chamber located at an aperture through a chamber wall, wherein the cell culture microdevice is configured at a scale to substantially enclose a single cell or cell mass therein. Embodiments of the cell culture microdevice may be suitable for in vitro fertilisation procedures and drug efficacy testing.

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