公开(公告)号：US20160030217A1

公开(公告)日：2016-02-04

申请号：US14881073

申请日：2015-10-12

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Mikael Trollsas ,  Michael H. Ngo ,  Boris Anukhin ,  Alexander Nikanorov ,  Syed Hossainy ,  John E. Papp ,  Dudley Jayasinghe ,  Zella Solter

IPC: A61F2/958 ,  A61F2/915 ,  B29C35/08 ,  A61F2/844

CPC classification number: A61F2/958 ,  A61F2/82 ,  A61F2/844 ,  A61F2/86 ,  A61F2/89 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/825 ,  A61F2002/91558 ,  A61F2002/91566 ,  A61F2002/91575 ,  A61F2002/9522 ,  A61F2210/0004 ,  A61F2210/0014 ,  A61F2210/0019 ,  A61F2210/0076 ,  A61F2230/0006 ,  A61F2230/0008 ,  A61F2250/0067 ,  A61F2250/0096 ,  A61F2250/0098 ,  A61L27/00 ,  A61L31/06 ,  A61L31/14 ,  B21D39/046 ,  B29C35/08 ,  B29C2035/0838 ,  B29K2067/046 ,  B29L2023/00 ,  B29L2031/7543 ,  Y10T29/49826 ,  Y10T29/4987 ,  Y10T29/49908 ,  Y10T29/49925 ,  Y10T29/49927 ,  C08L67/04 ,  C08L71/02

Abstract: A method of manufacturing a stent is disclosed. The stent includes a minimum crimped diameter such that in the minimum crimped diameter, a pair of stent rings, between which marker support structures reside, do not make contact with the marker support structures. The crimped profile of the stent of the present invention can be as small as the crimped profile of a same stent but without the marker support structures.

公开(公告)号：US20140205740A1

公开(公告)日：2014-07-24

申请号：US14226734

申请日：2014-03-26

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Dennis R. Orosa ,  John E. Papp ,  Hung T. Nguyen ,  Stephen D. Pacetti ,  Dudley Shelton Jayasinghe ,  Matthew J. Gillick

IPC: A61F2/82

CPC classification number: A61F2/82 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/608 ,  A61L2420/02 ,  A61L2420/08

Abstract: A coated implantable medical device and a method of coating an implantable medical device is disclosed, the method includes applying a composition onto the device and drying the composition at elevated temperature in an environment having increased relative humidity. A pre-screening method for a manufacturing lot of coated stents to determine the number of drug coating layers for a desired drug release rate is disclosed. The method including coating and testing small groups of stents, and applying the results of the tests to determine the number of drug coating layers to apply to the manufacturing lot of stents.

Abstract translation: 公开了涂覆的可植入医疗装置和涂覆可植入医疗装置的方法，所述方法包括将组合物施加到装置上并在具有相对湿度增加的环境中在升高的温度下干燥组合物。 公开了一种用于确定所需药物释放速率的药物涂层数量的涂层支架制造批次的预筛选方法。 该方法包括涂覆和测试小组支架，并应用测试结果确定应用于支架制造批次的药物涂层数量。

公开(公告)号：US20140058499A1

公开(公告)日：2014-02-27

申请号：US14042512

申请日：2013-09-30

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Mikael Trollsas ,  Michael H. Ngo ,  Boris Anukhin ,  Alexander Nikanorov ,  Syed Hossainy ,  John E. Papp ,  Dudley Jayasinghe ,  Zella Solter

IPC: A61F2/915

CPC classification number: A61F2/958 ,  A61F2/82 ,  A61F2/844 ,  A61F2/86 ,  A61F2/89 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/825 ,  A61F2002/91558 ,  A61F2002/91566 ,  A61F2002/91575 ,  A61F2002/9522 ,  A61F2210/0004 ,  A61F2210/0014 ,  A61F2210/0019 ,  A61F2210/0076 ,  A61F2230/0006 ,  A61F2230/0008 ,  A61F2250/0067 ,  A61F2250/0096 ,  A61F2250/0098 ,  A61L27/00 ,  A61L31/06 ,  A61L31/14 ,  B21D39/046 ,  B29C35/08 ,  B29C2035/0838 ,  B29K2067/046 ,  B29L2023/00 ,  B29L2031/7543 ,  Y10T29/49826 ,  Y10T29/4987 ,  Y10T29/49908 ,  Y10T29/49925 ,  Y10T29/49927 ,  C08L67/04 ,  C08L71/02

Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%. The scaffold has a pattern including an asymmetric closed cell connecting links connecting the closed cells.

Abstract translation: 医疗装置包括压接到具有膨胀气囊的导管的聚合物构架。 支架在被气囊部署之后，在支架的直径被挤压或压碎50％后，提供约90％的压碎回收率。 支架具有图案，其包括连接连接封闭单元的链接的非对称封闭单元。

公开(公告)号：US20130216695A1

公开(公告)日：2013-08-22

申请号：US13854007

申请日：2013-03-29

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Matthew J. Gillick ,  John E. Papp ,  Kevin Seiki ,  Hung Nguyen

IPC: A61F2/82

CPC classification number: F26B21/004 ,  A61F2/82 ,  B05B13/0207 ,  B05B15/00 ,  F26B3/04 ,  Y10T29/49433

Abstract: A coating device for coating a medical device with a drug-eluting material uses an in-process drying station between coats to improve a drug release profile. The drying station includes a heat nozzle configured for applying a uniform drying gas. A coating process using the dryer includes a closed-loop control for the gas between drying steps and an improved nozzle for producing more consistent spray patterns.

Abstract translation: 用药物洗脱物质涂覆医疗装置的涂覆装置使用涂层之间的过程中的干燥站来改善药物释放曲线。 干燥台包括配置成施加均匀干燥气体的热喷嘴。 使用干燥器的涂布方法包括用于干燥步骤之间的气体的闭环控制和用于产生更一致的喷雾图案的改进的喷嘴。