公开(公告)号：US20160184120A1

公开(公告)日：2016-06-30

申请号：US14979297

申请日：2015-12-22

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： John E. Papp ,  Hung T. Nguyen ,  Justin K. Elerath ,  Dion I. Herabadi ,  Michael T. Martins ,  Kirsten S. King ,  Scott H. Mueller ,  Coeta K. Peloquin ,  Stephen D. Pacetti

IPC: A61F2/958 ,  A61F2/915 ,  A61F2/91 ,  A61F2/966 ,  A61F2/844

CPC classification number: A61F2/958 ,  A61F2/844 ,  A61F2/91 ,  A61F2/915 ,  A61F2/966 ,  A61F2002/826 ,  A61F2002/9583 ,  A61F2210/0076 ,  A61F2250/0019 ,  A61F2250/0039

Abstract: Segmented scaffolds composed of disconnected scaffold segments are delivered to an implant site on a delivery balloon. The segments are crimped to the balloon and separated from each other by gaps. When the balloon is inflated the gaps between the disconnected scaffold segments stay constant. Pillowed or banded balloons are used to deliver the segments.

Abstract translation: 由断开的支架段组成的分段支架被输送到输送球囊上的植入部位。 这些片段被卷曲到球囊并且通过间隙彼此分离。 当气囊膨胀时，断开的支架段之间的间隙保持不变。 枕头或带状气球用于交付细分。

公开(公告)号：US20140008007A1

公开(公告)日：2014-01-09

申请号：US14024572

申请日：2013-09-11

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Yunbing Wang ,  Luis Vazquez ,  Hung T. Nguyen ,  Scott H. Mueller ,  Kathleen Yan

IPC: B29D23/00

CPC classification number: A61F2/82 ,  A61F2/95 ,  A61F2/958 ,  A61F2002/91566 ,  A61F2002/9522 ,  A61F2250/0067 ,  B29C53/30 ,  B29C67/0014 ,  B29D23/00 ,  B29D23/001 ,  Y10T29/49908 ,  Y10T29/49925 ,  Y10T29/49927 ,  Y10T29/4994 ,  Y10T29/49945 ,  Y10T29/53996

Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold is crimped to the catheter by a multi-step process for increasing scaffold-catheter yield following a crimping sequence. Damage reduction during a crimping sequence includes modifying blades of a crimper, adopting a multi-step crimping sequence, and inflating a supporting balloon to support the scaffold during crimping.

公开(公告)号：US09895244B2

公开(公告)日：2018-02-20

申请号：US14979297

申请日：2015-12-22

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： John E. Papp ,  Hung T. Nguyen ,  Justin K. Elerath ,  Dion I. Herabadi ,  Michael T. Martins ,  Kirsten S. King ,  Scott H. Mueller ,  Coeta K. Peloquin ,  Stephen D. Pacetti

IPC: A61F2/06 ,  A61F2/958 ,  A61F2/966 ,  A61F2/844 ,  A61F2/91 ,  A61F2/915 ,  A61F2/82

CPC classification number: A61F2/958 ,  A61F2/844 ,  A61F2/91 ,  A61F2/915 ,  A61F2/966 ,  A61F2002/826 ,  A61F2002/9583 ,  A61F2210/0076 ,  A61F2250/0019 ,  A61F2250/0039

Abstract: Segmented scaffolds composed of disconnected scaffold segments are delivered to an implant site on a delivery balloon. The segments are crimped to the balloon and separated from each other by gaps. When the balloon is inflated the gaps between the disconnected scaffold segments stay constant. Pillowed or banded balloons are used to deliver the segments.

公开(公告)号：US09642730B2

公开(公告)日：2017-05-09

申请号：US15089392

申请日：2016-04-01

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Michael H. Ngo ,  Mikael Trollsas ,  John E. Papp ,  Hung T. Nguyen ,  Dudley Jayasinghe ,  Ron Farnbach ,  Gregory C. Orr ,  Joshua Smith ,  Yongjin Xie ,  Yu-Chun Ku

IPC: B29C55/26 ,  A61F2/844 ,  A61F2/915 ,  A61F2/958 ,  A61F2/89 ,  B23K26/362 ,  B23K26/402 ,  A61F2/95 ,  B29L31/00 ,  B23K103/00 ,  B29C49/00 ,  B29C49/08 ,  B29K67/00

CPC classification number: A61F2/844 ,  A61F2/89 ,  A61F2/915 ,  A61F2/958 ,  A61F2002/91566 ,  A61F2002/91575 ,  A61F2002/91583 ,  A61F2002/9522 ,  A61F2002/9583 ,  A61F2210/0071 ,  A61F2230/0054 ,  A61F2230/0056 ,  B23K26/361 ,  B23K26/362 ,  B23K26/402 ,  B23K2103/42 ,  B23K2103/50 ,  B29C49/0073 ,  B29C49/08 ,  B29C55/26 ,  B29C2049/0089 ,  B29C2793/0009 ,  B29K2067/046 ,  B29L2031/753 ,  B29L2031/7534 ,  Y10T156/1002

Abstract: Methods for making scaffolds for delivery via a balloon catheter are described. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%. The scaffold structure has patterns that include an asymmetric or symmetric closed cell, and links connecting such closed cells.

公开(公告)号：US20160278952A1

公开(公告)日：2016-09-29

申请号：US15089392

申请日：2016-04-01

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Michael H. Ngo ,  Mikael Trollsas ,  John E. Papp ,  Hung T. Nguyen ,  Dudley Jayasinghe ,  Ron Farnbach ,  Gregory C. Orr ,  Joshua Smith ,  Yongjin Xie ,  Yu-Chun Ku

IPC: A61F2/844 ,  B23K26/402 ,  A61F2/89 ,  B23K26/362 ,  A61F2/958 ,  A61F2/915

CPC classification number: A61F2/844 ,  A61F2/89 ,  A61F2/915 ,  A61F2/958 ,  A61F2002/91566 ,  A61F2002/91575 ,  A61F2002/91583 ,  A61F2002/9522 ,  A61F2002/9583 ,  A61F2210/0071 ,  A61F2230/0054 ,  A61F2230/0056 ,  B23K26/361 ,  B23K26/362 ,  B23K26/402 ,  B23K2103/42 ,  B23K2103/50 ,  B29C49/0073 ,  B29C49/08 ,  B29C55/26 ,  B29C2049/0089 ,  B29C2793/0009 ,  B29K2067/046 ,  B29L2031/753 ,  B29L2031/7534 ,  Y10T156/1002

Abstract: Methods for making scaffolds for delivery via a balloon catheter are described. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%. The scaffold structure has patterns that include an asymmetric or symmetric closed cell, and links connecting such closed cells.

Abstract translation: 描述了通过球囊导管进行支架制备的方法。 支架在被气囊部署之后，在支架的直径被挤压或压碎50％后，提供约90％的压碎回收率。 支架结构具有包括不对称或对称闭孔的图案，以及连接这种闭孔的连接。

公开(公告)号：US20150238332A1

公开(公告)日：2015-08-27

申请号：US14700028

申请日：2015-04-29

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Yunbing Wang ,  Luis Sucy Vazquez ,  Hung T. Nguyen ,  Scott H. Mueller ,  Kathleen Yan

IPC: A61F2/82 ,  B29C53/30 ,  B29C67/00

CPC classification number: A61F2/82 ,  A61F2/95 ,  A61F2/958 ,  A61F2002/91566 ,  A61F2002/9522 ,  A61F2250/0067 ,  B29C53/30 ,  B29C67/0014 ,  B29D23/00 ,  B29D23/001 ,  Y10T29/49908 ,  Y10T29/49925 ,  Y10T29/49927 ,  Y10T29/4994 ,  Y10T29/49945 ,  Y10T29/53996

Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold is crimped to the catheter by a multi-step process for increasing scaffold-catheter yield following a crimping sequence. Damage reduction during a crimping sequence includes modifying blades of a crimper, adopting a multi-step crimping sequence, and inflating a supporting balloon to support the scaffold during crimping.

Abstract translation: 医疗装置包括压接到具有膨胀气囊的导管的聚合物构架。 通过多步骤方法将支架卷曲到导管，以在压接顺序之后增加支架导管产量。 在压接顺序期间的损伤减少包括修改卷边机的叶片，采用多步压接顺序，以及在压接期间使支撑气囊膨胀以支撑支架。

公开(公告)号：US09642729B2

公开(公告)日：2017-05-09

申请号：US14700028

申请日：2015-04-29

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Yunbing Wang ,  Luis Sucy Vazquez ,  Hung T. Nguyen ,  Scott H. Mueller ,  Kathleen Yan

IPC: A61F2/82 ,  B29C53/30 ,  B29C67/00 ,  A61F2/95 ,  B29D23/00 ,  A61F2/958 ,  A61F2/915

CPC classification number: A61F2/82 ,  A61F2/95 ,  A61F2/958 ,  A61F2002/91566 ,  A61F2002/9522 ,  A61F2250/0067 ,  B29C53/30 ,  B29C67/0014 ,  B29D23/00 ,  B29D23/001 ,  Y10T29/49908 ,  Y10T29/49925 ,  Y10T29/49927 ,  Y10T29/4994 ,  Y10T29/49945 ,  Y10T29/53996

Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold is crimped to the catheter by a multi-step process for increasing scaffold-catheter yield following a crimping sequence. Damage reduction during a crimping sequence includes modifying blades of a crimper, adopting a multi-step crimping sequence, and inflating a supporting balloon to support the scaffold during crimping.

公开(公告)号：US09084693B2

公开(公告)日：2015-07-21

申请号：US14024572

申请日：2013-09-11

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Yunbing Wang ,  Luis Vazquez ,  Hung T. Nguyen ,  Scott H. Mueller ,  Kathleen Yan

IPC: B29D23/00 ,  A61F2/958 ,  A61F2/95

CPC classification number: A61F2/82 ,  A61F2/95 ,  A61F2/958 ,  A61F2002/91566 ,  A61F2002/9522 ,  A61F2250/0067 ,  B29C53/30 ,  B29C67/0014 ,  B29D23/00 ,  B29D23/001 ,  Y10T29/49908 ,  Y10T29/49925 ,  Y10T29/49927 ,  Y10T29/4994 ,  Y10T29/49945 ,  Y10T29/53996

Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold is crimped to the catheter by a multi-step process for increasing scaffold-catheter yield following a crimping sequence. Damage reduction during a crimping sequence includes modifying blades of a crimper, adopting a multi-step crimping sequence, and inflating a supporting balloon to support the scaffold during crimping.

Abstract translation: 医疗装置包括压接到具有膨胀气囊的导管的聚合物构架。 通过多步骤方法将支架卷曲到导管，以在压接顺序之后增加支架导管产量。 在压接顺序期间的损伤减少包括修改卷边机的叶片，采用多步压接顺序，以及在压接期间使支撑气囊膨胀以支撑支架。

公开(公告)号：US09044352B2

公开(公告)日：2015-06-02

申请号：US14024577

申请日：2013-09-11

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Yunbing Wang ,  Luis Vazquez ,  Hung T. Nguyen ,  Scott H. Mueller ,  Kathleen Yan

IPC: B21D39/00 ,  A61F2/958 ,  A61F2/95 ,  B29D23/00

CPC classification number: A61F2/82 ,  A61F2/95 ,  A61F2/958 ,  A61F2002/91566 ,  A61F2002/9522 ,  A61F2250/0067 ,  B29C53/30 ,  B29C67/0014 ,  B29D23/00 ,  B29D23/001 ,  Y10T29/49908 ,  Y10T29/49925 ,  Y10T29/49927 ,  Y10T29/4994 ,  Y10T29/49945 ,  Y10T29/53996

Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold is crimped to the catheter by a multi-step process for increasing scaffold-catheter yield following a crimping sequence. Damage reduction during a crimping sequence includes modifying blades of a crimper, adopting a multi-step crimping sequence, and inflating a supporting balloon to support the scaffold during crimping.

公开(公告)号：US20140205740A1

公开(公告)日：2014-07-24

申请号：US14226734

申请日：2014-03-26

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Dennis R. Orosa ,  John E. Papp ,  Hung T. Nguyen ,  Stephen D. Pacetti ,  Dudley Shelton Jayasinghe ,  Matthew J. Gillick

IPC: A61F2/82

CPC classification number: A61F2/82 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/608 ,  A61L2420/02 ,  A61L2420/08

Abstract: A coated implantable medical device and a method of coating an implantable medical device is disclosed, the method includes applying a composition onto the device and drying the composition at elevated temperature in an environment having increased relative humidity. A pre-screening method for a manufacturing lot of coated stents to determine the number of drug coating layers for a desired drug release rate is disclosed. The method including coating and testing small groups of stents, and applying the results of the tests to determine the number of drug coating layers to apply to the manufacturing lot of stents.

Abstract translation: 公开了涂覆的可植入医疗装置和涂覆可植入医疗装置的方法，所述方法包括将组合物施加到装置上并在具有相对湿度增加的环境中在升高的温度下干燥组合物。 公开了一种用于确定所需药物释放速率的药物涂层数量的涂层支架制造批次的预筛选方法。 该方法包括涂覆和测试小组支架，并应用测试结果确定应用于支架制造批次的药物涂层数量。